Citation Impact
Citing Papers
In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34cdc2.
1994
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Interrelationships of human interferon-gamma with lymphotoxin and monocyte cytotoxin.
1984
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
Cell Death Mechanisms and the Immune System
1991
Synthesis, characterization, and evaluation of a novel bifunctional chelating agent for the lead isotopes 203Pb and 212Pb
2000
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
How Tumors Become Angiogenic
1996
Multiple Organ Damage Caused by Tumor Necrosis Factor and Prevented by Prior Neutrophil Depletion
1989
Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N′,N″,N‴-tris(acetic acid)cyclododecane (PA-DOTA)
1999
The Hallmarks of Cancer
2000 Standout
Preparation of high specific activity 86Y using a small biomedical cyclotron
2005
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
The Fibrinolytic System of the Vessel Wall and Its Role in the Control of Thrombosis
1990
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein
1988 StandoutNatureNobel
Isotachophoretic determination of stability constants of Ho and Y complexes with diethylenetriaminepentaacetic acid and 1,4,7,10-tetraazadodecane-N,N′,N″,N‴-tetraacetic acid
2003
Expression of Cerebellar Long-Term Depression Requires Postsynaptic Clathrin-Mediated Endocytosis
2000
Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma.
1994
Protein Tyrosine Kinase Activity and Its Endogenous Substrates in Rat Brain: A Subcellular and Regional Survey
1988
Molecular cloning and expression of a receptor for human tumor necrosis factor
1990
Matching chelators to radiometals for radiopharmaceuticals
2013 Standout
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
1991 StandoutNatureNobel
Deferoxamine as a chelator for 67Ga in the preparation of antibody conjugates
2005
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
Phosphorylation of RIM1α by PKA Triggers Presynaptic Long-Term Potentiation at Cerebellar Parallel Fiber Synapses
2003 StandoutNobel
Low molecular weight angiogenesis factors
1991
The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
1988 StandoutNobel
Melanoma imaging using 111In-, 86Y- and 68Ga-labeled CHX-A″-Re(Arg11)CCMSH
2009
1-Butyryl-Glycerol: A novel angiogenesis factor secreted by differentiating adipocytes
1990
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
1992 StandoutNobel
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor
1990
Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides
2008
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.
1986 StandoutNobel
Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance
1986 StandoutScienceNobel
Growth factors: Mechanism of action and relation to oncogenes
1984
Phosphorylation of receptors for insulin and insulin-like growth factor I. Effects of hormones and phorbol esters.
1986
The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor.
1985
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
The nucleotide sequence and the tissue-specific expression of Drosophila c-src
1985 StandoutNobel
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Amiloride directly inhibits growth factor receptor tyrosine kinase activity.
1985
Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I
1983 Nature
Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. Affinity-purified insulin-like growth factor I receptor kinase is activated by tyrosine phosphorylation of its beta subunit.
1986
Human tumor necrosis factor. Production, purification, and characterization.
1985
Synthesis and Preclinical Evaluation of Bifunctional Ligands for Improved Chelation Chemistry of 90Y and 177Lu for Targeted Radioimmunotherapy
2012
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Comparison of in vitro cell cytotoxic assays for tumor necrosis factor
1984
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.
1986 Standout
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
1998
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
In vitro production of rabbit macrophage tumor cell cytotoxin
1983
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
Macrophage-mediated cytotoxicity: role of a soluble macrophage cytotoxic factor similar to lymphotoxin and tumor necrosis factor.
1983
Covalently bound myristate in a lymphoma tyrosine protein kinase.
1984
A highly effective bifunctional ligand for radioimmunotherapy applications
2011
Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.
1986
Biosynthesis of the epidermal growth factor receptor in A431 cells.
1984
Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin
1985 StandoutScienceNobel
Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation.
1986
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1
1985
Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
1985 StandoutNobel
Phosphorylation of ribosomal protein S6 on serine after microinjection of the Abelson murine leukemia virus tyrosine-specific protein kinase into Xenopus oocytes.
1985 Nobel
Membranes from T and B lymphocytes have different patterns of tyrosine phosphorylation.
1984
Identification of a Protein with Homology to hsp90 That Binds the Type 1 Tumor Necrosis Factor Receptor
1995
Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the beta-subunit of type I insulin-like growth factor receptors of rat liver cells.
1985
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Insulin-like growth factor-I (IGF-I) stimulates tyrosine kinase activity in purified receptors from a rat liver cell line
1984
Cachectin: More Than a Tumor Necrosis Factor
1987 StandoutNobel
H4octapa: An Acyclic Chelator for 111In Radiopharmaceuticals
2012
Optimized conditions for chelation of yttrium-90-DOTA immunoconjugates.
1998
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
The Drosophila EGF receptor gene homolog: Conservation of both hormone binding and kinase domains
1985
Physical Parameters and Biological Stability of Yttrium(III) Diethylenetriaminepentaacetic Acid Derivative Conjugates
1998
Tyrosine phosphorylation of insulin receptor beta subunit activates the receptor tyrosine kinase in intact H-35 hepatoma cells.
1986
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
1985 StandoutNobel
Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.
1985
Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon.
1983
Seppuku and Autoimmunity
1992 StandoutScienceNobel
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.
1986
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.
1986
In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications
2002
The Human Erythrocyte Insulin-Like Growth Factor I Receptor:Characterization and Demonstration of Ligand-Stimulated Autophosphorylation
1986
Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro
1985 StandoutScience
Identification of the tyrosine protein kinase from LSTRA cells by use of site-specific antibodies.
1984
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
1987 StandoutNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity
1984 Nature
Expression and structure of the human NGF receptor
1986
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
1985 StandoutScience
Substrate specificities of tyrosine-specific protein kinases toward cytoskeletal proteins in vitro.
1986
Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.
1983
Genistein, a specific inhibitor of tyrosine-specific protein kinases.
1987 Standout
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
1984 StandoutNature
Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.
1983
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
1984 StandoutNobel
Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression
1985
Post-transcriptional control of the onset of DNA synthesis by an insulin-like growth factor.
1984
Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae.
1986
Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.
1987
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
1985
H4octapa-Trastuzumab: Versatile Acyclic Chelate System for 111In and 177Lu Imaging and Therapy
2013
Cellular and Molecular Regulation of Muscle Regeneration
2004 Standout
A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.
1985
Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.
1986
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
1986
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
1985 StandoutNatureNobel
Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor
1985 Science
Radiometals for Combined Imaging and Therapy
2012
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Characterization of distinct tyrosine-specific protein kinases in B and T lymphocytes.
1985
The Nature and Regulation of the Insulin Receptor: Structure and Function
1985
Molecular cloning of cDNA encoding human interleukin-2 receptor
1984 StandoutNatureNobel
Immunoprecipitation of Insulin Receptors from Cultured Human Lymphocytes (IM-9 Cells) by Antibodies to pp60 src
1985 Science
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Angiogenesis.
1992 Standout
Works of Frederick C. Kull being referenced
Yttrium-90 Chelation Properties of Tetraazatetraacetic Acid Macrocycles, Diethylenetriaminepentaacetic Acid Analogs, and a Novel Terpyridine Acyclic Chelator
1995
An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture
1987
Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice.
1989
Samarium-153 and Lutetium-177 Chelation Properties of Selected Macrocyclic and Acyclic Ligands
1998
Drug‐induced alterations of tumor necrosis factor‐mediated cytotoxicity: Discrimination of early versus late stage action
1990
Necrosin: purification and properties of a cytotoxin derived from a murine macrophage-like cell line.
1984
A monoclonal antibody to human insulin receptor
1982
Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.
1983
Monensin blocks the maturation of receptors for insulin and somatomedin C: Identification of receptor precursors
1983
Preliminary characterization of the tumor cell cytotoxin in tumor necrosis serum.
1981
Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells
2001
Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity.
1985
Chemical Identification of a Tumor-Derived Angiogenic Factor
1987 Science
Monoclonal antibodies to receptors for insulin and somatomedin-C.
1983
Possible requirement of internalization in the mechanism of in vitro cytotoxicity in tumor necrosis serum.
1981