Citation Impact
Citing Papers
HRD4/NPL4 Is Required for the Proteasomal Processing of Ubiquitinated ER Proteins
2001
PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines
2012
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
2000 StandoutScience
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
2015 StandoutScience
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
MHC class I–deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I–sufficient environment
2010
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment
2010
A Mouse Amidase Specific for N-terminal Asparagine
1996
The AAA team: related ATPases with diverse functions
1998
Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin–proteasome degradation
2001
Viral vectors for dendritic cell-based immunotherapy
2001
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
The Janus Face of the Archaeal Cdc48/p97 Homologue VAT: Protein Folding versus Unfolding
1999
Cut and trim: generating MHC class I peptide ligands
2001
Features of the dendritic cell lineage
2010 StandoutNobel
Active immunization against cancer with dendritic cells: The near future
2001 StandoutNobel
Confronting Complexity: the Interlink of Phototransduction and Retinoid Metabolism in the Vertebrate Retina
2001
A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System
2010
Imaging in the era of molecular oncology
2008 StandoutNature
Mobilization of Processed, Membrane-Tethered SPT23 Transcription Factor by CDC48UFD1/NPL4, a Ubiquitin-Selective Chaperone
2001
HDAC6 is a microtubule-associated deacetylase
2002 StandoutNature
The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor
1998
The Human T Cell Response to Melanoma Antigens
2006
NK cell education: not an on-off switch but a tunable rheostat
2009
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
2013
A listing of human tumor antigens recognized by T cells
2001
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
2001 Nature
The cell biology of antigen presentation in dendritic cells
2001
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
2005
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Conditional Protein Alleles Using Knockin Mice and a Chemical Inducer of Dimerization
2003
Inhibition of Proteasome Activity Induces Concerted Expression of Proteasome Genes and de Novo Formation of Mammalian Proteasomes
2003
Hermansky–Pudlak syndrome: a disease of protein trafficking and organelle function
2006
Towards patient‐specific tumor antigen selection for vaccination
2002
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing
2000
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
2014
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
A listing of human tumor antigens recognized by T cells: March 2004 update
2004
ATPase Activity of p97-Valosin-containing Protein (VCP)
2003
Tumor‐specific shared antigenic peptides recognized by human T cells
2002
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
Antigen processing by the proteasome
2001
Optimization and validation of a robust human T-cell culture method for monitoring phenotypic and polyfunctional antigen-specific CD4 and CD8 T-cell responses
2009 StandoutNobel
Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi
1992 Nature
Rpn4p acts as a transcription factor by binding to PACE, a nonamer box found upstream of 26S proteasomal and other genes in yeast
1999
The Ubiquitin System and the N-End Rule Pathway
2000
Antigen Processing and Remodeling of the Endosomal Pathway: Requirements for Antigen Cross-Presentation
2012
Control of cross‐presentation during dendritic cell maturation
2004
The N‐end rule pathway of protein degradation
1997
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Antigens for cancer immunotherapy
2008
A Novel Ubiquitination Factor, E4, Is Involved in Multiubiquitin Chain Assembly
1999
Cancer immunotherapy comes of age
2011 StandoutNature
Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells
2001
The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain
1999
Structure of 20S proteasome from yeast at 2.4Å resolution
1997 StandoutNatureNobel
Recognition of the polyubiquitin proteolytic signal
2000
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Ubiquitin fusion technique and its descendants
2000
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway
2000 Nature
The function of the proteasome system in MHC class I antigen processing
2000
RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro
2000
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
2001 Nature
Identification of human tumor antigens and its implications for diagnosis and treatment of cancer
2004
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
RING domains: master builders of molecular scaffolds?
2000
Current perspectives of natural killer cell education by MHC class I molecules
2010
The ubiquitin system
1997
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein
1999
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
A protein–protein interaction map of the Caenorhabditis elegans 26S proteasome
2001
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein–Barr virus nuclear antigen 1
1997 StandoutNobel
Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells
2000
The proteasome activator 11 S REG (PA28) and Class I antigen presentation
1999
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice
2001 StandoutNobel
Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming
2007
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit
2001
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70
2000 StandoutNobel
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Cytotoxic T Lymphocyte Epitopes of HIV-1 Nef
2000
The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM
2005
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Peptide Binding to Major Histocompatibility Complex Molecules
1993
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Tumor rejection antigen gp96/grp94 is an ATPase: implications for protein folding and antigen presentation.
1993
Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways
2001
Influences of Transporter Associated with Antigen Processing (TAP) on the Repertoire of Peptides Associated with the Endoplasmic Reticulum–resident Stress Protein gp96
1997
Analysis of the B‐cell repertoire against antigens expressed by human neoplasms
2002
Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma.
2003
Identification of the retinol‐binding protein (RBP) interaction site and functional state of RBPs for the membrane receptor
2007
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Antitumor Monoclonal Antibodies Enhance Cross-Presentation of Cellular Antigens and the Generation of Myeloma-specific Killer T Cells by Dendritic Cells
2002
Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.
1994
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Detecting and Measuring Cotranslational Protein Degradation in Vivo
2000 Science
The Conserved Npl4 Protein Complex Mediates Proteasome-dependent Membrane-bound Transcription Factor Activation
2001
Effector Function of Human Tumor-Specific CD8 T Cells in Melanoma Lesions: A State of Local Functional Tolerance
2004
Mage-3 and Influenza-Matrix Peptide-Specific Cytotoxic T Cells Are Inducible in Terminal Stage HLA-A2.1+ Melanoma Patients by Mature Monocyte-Derived Dendritic Cells
2000
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
New Biarsenical Ligands and Tetracysteine Motifs for Protein Labeling in Vitro and in Vivo: Synthesis and Biological Applications
2002 StandoutNobel
AAA-ATPase p97/Cdc48p, a Cytosolic Chaperone Required for Endoplasmic Reticulum-Associated Protein Degradation
2002
Molecular Genetics of Human Retinal Disease
1999
HUMAN T CELL RESPONSES AGAINST MELANOMA
2005
Altered Activity, Social Behavior, and Spatial Memory in Mice Lacking the NTAN1p Amidase and the Asparagine Branch of the N-End Rule Pathway
2000
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Identification of tumor antigens as potential target antigens for immunotherapy by serological expression cloning
2004
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Neoantigens in cancer immunotherapy
2015 StandoutScience
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX
1996
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Antigen Presentation and T Cell Stimulation by Dendritic Cells
2002
Physical association of ubiquitin ligases and the 26S proteasome
2000
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Effects of interferon treatment on the antiviral T-cell response in hepatitis C virus genotype 1b- and genotype 2c-infected patients
1997 StandoutNobel
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
The N-end rule: functions, mysteries, uses.
1996
Proteasomal Proteomics: Identification of Nucleotide-sensitive Proteasome-interacting Proteins by Mass Spectrometric Analysis of Affinity-purified Proteasomes
2000
Solubilization and purification of the retinol-binding protein receptor from human placental membranes
1994
Works of Frédéric Lévy being referenced
Interactions of Ly49 Family Receptors with MHC Class I Ligands in trans and cis
2007
Lack of tumor recognition by hTERT peptide 540-548-specific CD8+ T cells from melanoma patients reveals inefficient antigen processing
2001
Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen
2006
ATP is required for in vitro assembly of MHC class I antigens but not to transfer of peptides acrosss the ER membrane
1991
Early events in the assembly of MHC class I antigens
1993
Analysis of a conditional degradation signal in yeast and mammalian cells
1999
Processing of Some Antigens by the Standard Proteasome but Not by the Immunoproteasome Results in Poor Presentation by Dendritic Cells
2000
Antigenicity and immunogenicity of Melan‐A/MART‐1 derived peptides as targets for tumor reactive CTL in human melanoma
2002
Combination of lentivector immunization and low‐dose chemotherapy or PD‐1/PD‐L1 blocking primes self‐reactive T cells and induces anti‐tumor immunity
2011
Bivalent Inhibitor of the N-end Rule Pathway
1999
A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHC Class I for Natural Killer Cell Education
2009
The Production of a New MAGE-3 Peptide Presented to Cytolytic T Lymphocytes by HLA-B40 Requires the Immunoproteasome
2002
Ubiquitylation of a Melanosomal Protein by HECT-E3 Ligases Serves as Sorting Signal for Lysosomal Degradation
2005
The retinal pigment epithelial membrane receptor for plasma retinol-binding protein. Isolation and cDNA cloning of the 63-kDa protein.
1993
Using ubiquitin to follow the metabolic fate of a protein.
1996
Proteasome-Assisted Identification of a SSX-2-Derived Epitope Recognized by Tumor-Reactive CTL Infiltrating Metastatic Melanoma
2002
Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens
1990
The Melanocytic Protein Melan‐A/MART‐1 Has a Subcellular Localization Distinct from Typical Melanosomal Proteins
2002
Cross-presenting human γδ T cells induce robust CD8 + αβ T cell responses
2009
Identification and characterization of a mammalian protein interacting with 20S proteasome precursors
2000
Modulation of Proteasomal Activity Required for the Generation of a Cytotoxic T Lymphocyte–defined Peptide Derived from the Tumor Antigen MAGE-3
1999
The Final N-Terminal Trimming of a Subaminoterminal Proline-Containing HLA Class I-Restricted Antigenic Peptide in the Cytosol Is Mediated by Two Peptidases
2002
Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae.
1996
Induction of Potent Antitumor CTL Responses by Recombinant Vaccinia Encoding a Melan-A Peptide Analogue
2000
Processing of Tumor-Associated Antigen by the Proteasomes of Dendritic Cells ControlsIn vivoT-Cell Responses
2006
Naturally processed and concealed HLA-A2.1-restricted epitopes from tumor-associated antigen tyrosinase-related protein-2
2000
Translocation of peptides through microsomal membranes is a rapid process and promotes assembly of HLA-B27 heavy chain and beta 2-microglobulin translated in vitro.
1991