Citation Impact
Citing Papers
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Molecular and Cellular Aspects of Thiol–Disulfide Exchange
1990
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Haemodynamic definitions and updated clinical classification of pulmonary hypertension
2018 Standout
Genetic origins and clinical phenotype of familial and acquired erythrocytosis and thrombocytosis
2008
Long-Term Outcome and Evaluation of Organ Function in Pediatric Patients Undergoing Haploidentical and Matched Related Hematopoietic Cell Transplantation for Sickle Cell Disease
2013
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis
2009 StandoutNobel
Management of Sickle Cell Disease
2014
SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability
2009 StandoutNobel
The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
1999 StandoutNature
Duration of Red-Cell Storage and Complications after Cardiac Surgery
2008 Standout
A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events
2015
Hemoglobin disorders and endothelial cell interactions
2009
Studies on sickled erythrocytes provide evidence that the asymmetric distribution of phosphatidylserine in the red cell membrane is maintained by both ATP-dependent translocation and interaction with membrane skeletal proteins
1988
Review: Hemodynamic Characteristics and Outcomes of Sickle Cell Disease Associated Pulmonary Hypertension
2016
Eicosanoids in sickle cell disease: Potential relevance of neutrophil leukotriene B4 to disease pathophysiology
2002
Pulmonary hypertension in sickle cell disease
2015
Haemoglobinopathies and the rheumatologist
2016
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Erythroid adhesion molecules in sickle cell disease: Effect of hydroxyurea
2008
Pathogenesis and Treatment of Sickle Cell Disease
1997
Mortality in Adults With Sickle Cell Disease and Pulmonary Hypertension
2012
Acute chest syndrome of sickle cell disease: new light on an old problem
2001
Human red cell Aquaporin CHIP. II. Expression during normal fetal development and in a novel form of congenital dyserythropoietic anemia.
1994 StandoutNobel
Hemoglobin: Structure, Function and Allostery
2020
Nonenzymatic Deamidation of Asparaginyl and Glutaminyl Residues in Protein
1991
Exercise capacity and haemodynamics in patients with sickle cell disease with pulmonary hypertension treated with bosentan: results of the ASSET studies
2010
Effects of storage on efficacy of red cell transfusion: When is it not safe?
2003
Cardiovascular complications and risk of death in sickle-cell disease
2016
Evidence review of hydroxyurea for the prevention of sickle cell complications in low-income countries
2013
Management of Patients with Sickle Cell Disease Using Transfusion Therapy
2016
Pediatric Pulmonary Hypertension
2013
New therapies in sickle cell disease
2002
Cerebrovascular disease associated with sickle cell pulmonary hypertension
2006
Hemoglobin Jamaica Plain — A Sickling Hemoglobin with Reduced Oxygen Affinity
2004
Infection in sickle cell disease: A review
2009
The molecular basis of blood coagulation
1988 Standout
Preliminary Assessment of Inhaled Nitric Oxide for Acute Vaso-occlusive Crisis in Pediatric Patients With Sickle Cell Disease
2003
Membrane Mechanisms and Intracellular Signalling in Cell Volume Regulation
1995
Evaluation of a Density-Based Rapid Diagnostic Test for Sickle Cell Disease in a Clinical Setting in Zambia
2014
Early detection of pulmonary arterial hypertension
2014
Physical Therapy Alone Compared with Core Decompression and Physical Therapy for Femoral Head Osteonecrosis in Sickle Cell Disease
2006
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Sickle Cell Disease
2017
Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels
2003
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
2002 StandoutNobel
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Band 3 and glycophorin are progressively aggregated in density-fractionated sickle and normal red blood cells. Evidence from rotational and lateral mobility studies.
1993
Cardiomyopathy With Restrictive Physiology in Sickle Cell Disease
2016
Redefining pulmonary hypertension
2017
Outcome of Sickle Cell Anemia
2005
Sickle cell disease: renal manifestations and mechanisms
2015
Unusually large von willebrand factor multimers preferentially promote young sickle and nonsickle erythrocyte adhesion to endothelial cells
1993
Differential control of band 3 lateral and rotational mobility in intact red cells.
1994 StandoutNobel
The Missing Diversity in Human Genetic Studies
2019 Standout
Reconstructing sickle cell disease: A data‐based analysis of the “hyperhemolysis paradigm” for pulmonary hypertension from the perspective of evidence‐based medicine
2010
Investigational drugs in sickle cell anemia
2009
Air pollution and health
2002 Standout
A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger
2008
Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry
2012
Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
1998 Standout
Updated Clinical Classification of Pulmonary Hypertension
2013 Standout
Nitric oxide's reactions with hemoglobin: a view through the SNO-storm
2003
Sickle cell disease: no longer a single gene disorder
2001
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
Sickle-cell disease
2010 Standout
Sickle Cell Disease in a Patient with Sickle Cell Trait and Compound Heterozygosity for Hemoglobin S and Hemoglobin Quebec–Chori
1991
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
Elevated Pulse Pressure is Associated with Hemolysis, Proteinuria and Chronic Kidney Disease in Sickle Cell Disease
2014
Deconstructing sickle cell disease: Reappraisal of the role of hemolysis in the development of clinical subphenotypes
2006
N9 Neuraminidase Complexes with Antibodies NC41 and NC10: Empirical Free Energy Calculations Capture Specificity Trends Observed with Mutant Binding Data
1994
Significant haemoglobinopathies: guidelines for screening and diagnosis
2010
Sickle red cell dehydration: mechanisms and interventions
2002
Antenatal diagnosis and palliative treatment of non‐immune hydrops fetalis secondary to fetal parvovirus B19 infection
1989
Particulate air pollution and the blood
1999
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
2002
Therapeutic Strategies for Prevention of Sickle Cell Dehydration
2001
GenetiC Mechanisms Underlying Regulation of Hemoglobin Mass
2007
Disorders of red cell volume regulation
2013
Molecular basis for polycythemia
1999
Pulmonary Complications of Sickle Cell Disease
2008
Disorders of Iron Metabolism
1999 Standout
Long-term hydroxyurea treatment in young sickle cell patients
1999
The paradox of hemoglobin SC disease
2003
Red cell indices in classification and treatment of anemias
2013
Absence of Erythroblast Macrophage Protein (Emp) Leads to Failure of Erythroblast Nuclear Extrusion
2006
Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation
2011
Pulmonary Complications of Sickle Cell Disease
2012
Neonatal Hemochromatosis
1992
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology
1991
Extracellular DNA traps promote thrombosis
2010 Standout
Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: Two‐year results including pharmacokinetics and concomitant hydroxyurea
2013
Biochemical surrogate markers of hemolysis do not correlate with directly measured erythrocyte survival in sickle cell anemia
2016
The spleen and sickle cell disease: the sick(led) spleen
2014
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Maturation of the hemostatic system during childhood
1992 Standout
Percutaneous Implantation of Autologous Bone Marrow Osteoprogenitor Cells as Treatment of Bone Avascular Necrosis Related to Sickle Cell Disease
2008
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
THE GREEN FLUORESCENT PROTEIN
1998 StandoutNobel
Hemostatic Alterations in Sickle Cell Disease: Relationships to Disease Pathophysiology
2001
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice
2012
Targeted Gene Deletion Demonstrates that Cell Adhesion Molecule ICAM-4 is Critical for \nErythroblastic Island Formation
2006
Nitric oxide therapy in sickle cell disease
2001
Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K+]oregulation
1997
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
2002
Prevalence and Risk Factors for Pulmonary Arterial Hypertension in a Large Group of β-Thalassemia Patients Using Right Heart Catheterization
2013
Phospholipase A2 levels in acute chest syndrome of sickle cell disease
1996
The HIF Pathway and Erythrocytosis
2011
Divergent Nitric Oxide Bioavailability in Men and Women With Sickle Cell Disease
2003
The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry
1993 StandoutNobel
JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway
2012
Heparin inhibits the flow adhesion of sickle red blood cells to P-selectin
2002
Abnormal processing of beta Knossos RNA
1984
Role of erythrocyte phosphatidylserine in sickle red cell–endothelial adhesion
2002
A Hot Spot of Binding Energy in a Hormone-Receptor Interface
1995 StandoutScience
Delayed hemolytic transfusion reaction in children with sickle cell disease
2011
Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.
1994 StandoutNobel
Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia
2013
Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor.
1986
Dehydration of transferrin receptor-positive sickle reticulocytes during continuous or cyclic deoxygenation: role of KCl cotransport and extracellular calcium
1996
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Identification of the Cystic Fibrosis Gene: Genetic Analysis
1989 StandoutScience
Estimated pulmonary artery systolic pressure and sickle cell disease: a meta‐analysis and systematic review
2015
In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue
1986 StandoutScience
High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors
2013
Membrane Transport in Sickle Cell Disease
2002
Transmembrane mobility of phospholipids in sickle erythrocytes: effect of deoxygenation on diffusion and asymmetry
1991
Pathophysiology and treatment of pulmonary hypertension in sickle cell disease
2016
Transfusion therapy for sickle cell disease: a balancing act
2013
The Gárdos channel: a review of the Ca2+-activated K+ channel in human erythrocytes
2003
Iron-Deficiency Anemia
2015 Standout
Particulate Matter Air Pollution and Cardiovascular Disease
2010 Standout
Factors associated with survival in a contemporary adult sickle cell disease cohort
2014
How I manage cerebral vasculopathy in children with sickle cell disease
2015
Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum.
1996 Standout
Sickle cell disease related mortality in the United States (1999-2009)
2013
Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease
2016
Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
1992 StandoutScience
Amino-terminal processing of proteins: hemoglobin South Florida, a variant with retention of initiator methionine and N alpha-acetylation.
1985
Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2
1994 StandoutNobel
Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management
2012
Changing practice: red blood cell typing by molecular methods for patients with sickle cell disease
2015
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
Density-based separation in multiphase systems provides a simple method to identify sickle cell disease
2014
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Urea alters set point volume for K-Cl cotransport, Na-H exchange, and Ca-Na exchange in dog red blood cells
1993
The silent carrier allele: β thalassemia without a mutation in the β-globin gene or its immediate flanking regions
1984 StandoutNobel
Affinity purification of ubiquitin-protein ligase on immobilized protein substrates. Evidence for the existence of separate NH2-terminal binding sites on a single enzyme.
1990 StandoutNobel
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Oral magnesium pidolate: effects of long‐term administration in patients with sickle cell disease
2000
Ubiquitin-mediated protein degradation.
1988 StandoutNobel
Isolation of fetal DNA from nucleated erythrocytes in maternal blood.
1990
Bone Marrow Failure Syndromes
1999
Silent β-Thalassemia Associated with Hb Knossos β27 (B9) Ala→Ser in Algeria
1983
HbS-Oman Heterozygote: A New Dominant Sickle Syndrome
1998
Evolutionarily Conserved Pathways of Energetic Connectivity in Protein Families
1999 Science
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel
Erythrocyte P Antigen: Cellular Receptor for B19 Parvovirus
1993 StandoutScience
Swelling activation of K-Cl cotransport in LK sheep erythrocytes: a three-state process.
1993
Cotranslational amino-terminal processing of cytosolic proteins. Cell-free expression of site-directed mutants of human hemoglobin.
1988
Quantification of the close association between DNA haplotypes and specific β-thalassaemia mutations in Mediterraneans
1984 Nature
Works of Frédéric Galactéros being referenced
Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation
2010
The Lutheran Blood Group Glycoproteins, the Erythroid Receptors for Laminin, Are Adhesion Molecules
1998
A Hemodynamic Study of Pulmonary Hypertension in Sickle Cell Disease
2011
The Natural History of Asymptomatic Osteonecrosis of the Femoral Head in Adults with Sickle Cell Disease
2006
Clinical Follow-Up of Hydroxyurea-Treated Adults with Sickle Cell Disease
2010
Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease.
1997
Mutagenic dissection of hemoglobin cooperativity: Effects of amino acidalteration on subunit assembly of oxy and deoxy tetramers
1992
Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen
2011
Acute Chest Syndrome in Adults With Sickle Cell Disease
2000
Pulmonary Hypertension and Cor Pulmonale during Severe Acute Chest Syndrome in Sickle Cell Disease
2008
Clinical management of adult sickle-cell disease
2012
First evidence of subclinical renal tubular injury during sickle-cell crisis
2014
The involvement of the Ca-dependent K channel and of the KCl co-transport in sickle cell dehydration during cyclic deoxygenation
1994
Role of Lu/BCAM in abnormal adhesion of sickle red blood cells to vascular endothelium
2008
Environmental Influences on Daily Emergency Admissions in Sickle-Cell Disease Patients
2014
A study of 36 unrelated cases with pure erythrocytosis revealed three new mutations in the erythropoietin receptor gene
2008
Maternal mortality among women with sickle-cell disease in France, 1996–2009
2015
Aggregation of mononuclear and red blood cells through an 4 1-Lu/basal cell adhesion molecule interaction in sickle cell disease
2010
Priapism following splenectomy in an unstable hemoglobin: Hemoglobin Olmsted β141 (H19) Leu→Arg
1996
Early intermittent noninvasive ventilation for acute chest syndrome in adults with sickle cell disease: a pilot study
2010
Resveratrol, a natural dietary phytoalexin, possesses similar properties to hydroxyurea towards erythroid differentiation
2001
Acute kidney injury in sickle patients with painful crisis or acute chest syndrome and its relation to pulmonary hypertension
2010
Rituximab for prevention of delayed hemolytic transfusion reaction in sickle cell disease
2007
Bloodstream Infection in Adults With Sickle Cell Disease
2006
Haematological determinants of cardiac involvement in adults with sickle cell disease
2015
Hemoglobin roanne [α94(G1) asp å glu]: a variant of the α1β2 interface with an unexpected high oxygen affinity
1995
Partial C antigen in sickle cell disease patients: clinical relevance and prevention of alloimmunization
2009
A new sickle cell disease phenotype associating Hb S trait, severe pyruvate kinase deficiency (PK Conakry), and an α2 globin gene variant (Hb Conakry)
1998
Delayed hemolytic transfusion reaction in sickle cell disease patients: evidence of an emerging syndrome with suicidal red blood cell death
2009
Induced Sputum versus Bronchoalveolar Lavage during Acute Chest Syndrome in Sickle Cell Disease
2003
Pulmonary Artery Thrombosis during Acute Chest Syndrome in Sickle Cell Disease
2011
Clinical manifestations and erythrocyte adhesion to endothelium in sickle cell syndrome
1985
2015 Clinical trials update in sickle cell anemia
2015
Acquired unbalanced hemoglobin chain synthesis during HIV infection.
1993
Endothelial dysfunction in patients with sickle cell disease is related to selective impairment of shear stress–mediated vasodilation
2001
Hemoglobins with High Oxygen Affinity Leading to Erythrocytosis. New Variants and New Concepts
2005
Covalent binding of glutathione to hemoglobin. I. Inhibition of hemoglobin S polymerization.
1986
Deformities of the hip in adults who have sickle-cell disease and had avascular necrosis in childhood. A natural history of fifty-two patients.
1991
Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome
2010
Hemoglobin Saint Mandé β102 (G4) Asn → Tyr: a new low oxygen affinity variant
1981
Characteristics and Outcome of Connective Tissue Diseases in Patients with Sickle-Cell Disease: Report of 30 Cases
2008
Inhibition of K+ efflux and dehydration of sickle cells by [(dihydroindenyl)oxy]alkanoic acid: an inhibitor of the K+ Cl- cotransport system.
1989
Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes
1992
Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis
2012
Structural study of hemoglobin Knossos, β27 (B9) Ala→Ser
1982
Hemoglobins With High Oxygen Affinity Leading to Erythrocytosis. New Variants and New Concepts
2005
A new Case of Hemoglobin Providence (α2β282 (Ef6) Lys → Asn or Asp) Discovered in a French Caucasian Family. Structural and Functional Studies
1985
Six Months of Hydroxyurea Reduces Albuminuria in Patients with Sickle Cell Disease
2015
The calmodulin-stimulated (Ca2+ + Mg2+)-ATPase in hemoglobin S erythrocyte membranes: effects of sickling and oxidative agents
1987
Abnormality of phospholipid transverse diffusion in sickle erythrocytes.
1985
The nonexpression of CD36 on reticulocytes and mature red blood cells does not modify the clinical course of patients with sickle cell anemia
2001
Hemoglobin Thionville. An alpha-chain variant with a substitution of a glutamate for valine at NA-1 and having an acetylated methionine NH2 terminus.
1992
Compound heterozygosity in a complete erythrocyte bisphosphoglycerate mutase deficiency
1992
Hematological Values of 163 Normal Fetuses between 18 and 30 Weeks of Gestation
1986
Hb Taybe (alpha 38 or 39 THR deleted): an alpha-globin defect, silent in the heterozygous state and producing severe hemolytic anemia in the homozygous.
1994
Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619.
1993
Hb Marseille [α2β2 N methionyl ‐ 2 (NA2) His → Pro]: a new β chain variant having an extended N‐terminus
1984
A randomized, controlled clinical trial of ketoprofen for sickle-cell disease vaso-occlusive crises in adults
2009
Hemoglobin S Antilles: a variant with lower solubility than hemoglobin S and producing sickle cell disease in heterozygotes.
1986