Citation Impact
Citing Papers
Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target
2010
Privileged Diazepine Compounds and Their Emergence as Bromodomain Inhibitors
2014
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
Structures of hepatitis C virus nonstructural proteins required for replicase assembly and function
2013 StandoutNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Subunit disassembly and inhibition of TNFα by a semi-synthetic bicyclic peptide
2015 StandoutNobel
New horizons in hepatitis C antiviral therapy with direct-acting antivirals
2013
The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors
2012
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
Inhibitors of c-Jun N-terminal kinases—JuNK no more?
2007
SwissParam: A fast force field generation tool for small organic molecules
2011 Standout
NS5A - From Obscurity to New Target for HCV Therapy
2008
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
2013
Discovery of a Non-Peptidic Inhibitor of West Nile Virus NS3 Protease by High-Throughput Docking
2009
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
2017 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Taming a beast: lessons from the domestication of hepatitis C virus
2019 StandoutNobel
Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery
2013 Standout
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Tracking the Evolution of MultipleIn VitroHepatitis C Virus Replicon Variants under Protease Inhibitor Selection Pressure by 454 Deep Sequencing
2010
Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV)
2012
Enhancement of the Replication of Hepatitis C Virus Replicons of Genotypes 1 to 4 by Manipulation of CpG and UpA Dinucleotide Frequencies and Use of Cell Lines Expressing SECL14L2 for Antiviral Resistance Testing
2016
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Structural Analysis of Asunaprevir Resistance in HCV NS3/4A Protease
2014
Efficient Replication of Genotype 3a and 4a Hepatitis C Virus Replicons in Human Hepatoma Cells
2012 StandoutNobel
Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor
2014
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
In Vitro Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435
2010
TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage
2012
A Refined Model of the HCV NS5A Protein Bound to Daclatasvir Explains Drug-Resistant Mutations and Activity against Divergent Genotypes
2014 StandoutNobel
Enantioselective palladium(0)-catalyzed intramolecular cyclopropane functionalization: access to dihydroquinolones, dihydroisoquinolones and the BMS-791325 ring system
2015
Response of Hepatitis C Virus to Long-Term Passage in the Presence of Alpha Interferon: Multiple Mutations and a Common Phenotype
2013 StandoutNobel
Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery
2011
Increased Replicative Fitness Can Lead to Decreased Drug Sensitivity of Hepatitis C Virus
2014 StandoutNobel
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
2019 StandoutNobel
Macrocyclic Drugs and Clinical Candidates: What Can Medicinal Chemists Learn from Their Properties?
2013
Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
2015
Hepatitis C Virus Genotype 5a Subgenomic Replicons for Evaluation of Direct-Acting Antiviral Agents
2014 StandoutNobel
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Single‐molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase
2017 StandoutNobel
Structure-Based Design of a Benzodiazepine Scaffold Yields a Potent Allosteric Inhibitor of Hepatitis C NS5B RNA Polymerase
2009
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Works of Frédéric Delouvroy being referenced
Discovery of novel potent and selective dipeptide hepatitis C virus NS3/4A serine protease inhibitors
2008
Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors
2007
1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors
2008
In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor
2009