Frédéric Delobel

Modular click chemistry libraries for functional screens using a diazotizing reagent

Opportunities and challenges in phenotypic drug discovery: an industry perspective

Human hepatocytes: Isolation, cryopreservation and applications in drug development

Drug repurposing: progress, challenges and recommendations

Microfluidic organs-on-chips

Phenotypic screening with target identification and validation in the discovery and development of E3 ligase modulators

Evaluation of a Liver Microfluidic Biochip to Predict In Vivo Clearances of Seven Drugs in Rats

PROTAC targeted protein degraders: the past is prologue

Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies

Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems

The Many Roles for Fluorine in Medicinal Chemistry

In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease

Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective

Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery

Impact of serum on clearance predictions obtained from suspensions and primary cultures of rat hepatocytes

Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance