Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
2011
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Potential for therapeutic manipulation of the UPR in disease
2013
TRPM8-independent Menthol-induced Ca2+ Release from Endoplasmic Reticulum and Golgi
2006
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
The mystery of nonclassical protein secretion
2003
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508delCFTR
2015 Standout
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
1999
Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds
2001
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules
2006
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Differential and Simultaneous Adenosine Di- and Triphosphate Binding by MutS
2003 StandoutNobel
Hydrolytically Deficient MutS E694A Is Defective in the MutL-dependent Activation of MutH and in the Mismatch-dependent Assembly of the MutS · MutL · Heteroduplex Complex
2003 StandoutNobel
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
New insights into the mechanism of IL-1β maturation
2003
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Submucosal Glands and Airway Defense
2004
Molecular Cloning of the Human ATP-Binding Cassette Transporter 1 (hABC1): Evidence for Sterol-Dependent Regulation in Macrophages
1999
Treatment of Obesity with Celastrol
2015 Standout
CFTR, Mucins, and Mucus Obstruction in Cystic Fibrosis
2012
Cell Death
2004 Standout
G Protein-coupled Receptor Kinase 6A Phosphorylates the Na+/H+ Exchanger Regulatory Factor via a PDZ Domain-mediated Interaction
1999 StandoutNobel
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
1999
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
2006
Altered Cytokine Production in Mice Lacking P2X7Receptors
2001
PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
2001
TRPM8 Is Required for Cold Sensation in Mice
2007 StandoutNobel
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.
2000
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
1999
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
The Therapeutic Potential of Modifying Inflammasomes and NOD-Like Receptors
2013
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Apoptosis: The importance of being eaten
1998
Airway Mucus Function and Dysfunction
2010 Standout
The Inflammasomes
2010 Standout
The role of phosphatidylserine in recognition of apoptotic cells by phagocytes
1998
Chloride channels as drug targets
2008
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy
2006
The Hallmarks of Aging
2013 Standout
Non-synaptic ion channels in insects — basic properties of currents and their modulation in neurons and skeletal muscles
2001
CURCUMIN: THE INDIAN SOLID GOLD
2007 Standout
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
2011 Standout
Atherosclerosis
2001 Standout
An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton
1998
Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis
2006 Standout
Phenylglycine and Sulfonamide Correctors of Defective ΔF508 and G551D Cystic Fibrosis Transmembrane Conductance Regulator Chloride-Channel Gating
2005
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway
1999
Inflammasomes in health and disease
2012 StandoutNature
Lack of Neutrophil Elastase Reduces Inflammation, Mucus Hypersecretion, and Emphysema, but Not Mucus Obstruction, in Mice with Cystic Fibrosis–like Lung Disease
2014
Hydrogen Sulfide Protects HT22 Neuronal Cells from Oxidative Stress
2006
NUC-1, aCaenorhabditis elegansDNase II homolog, functions in an intermediate step of DNA degradation during apoptosis
2000 StandoutNobel
Anion Transport in Heart
2000
Inflammation and its genesis in cystic fibrosis
2015
P2X7 Receptor-Dependent Blebbing and the Activation of Rho-Effector Kinases, Caspases, and IL-1β Release
2003
High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
2000
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells
2008
Extremely Active Organocatalysts Enable a Highly Enantioselective Addition of Allyltrimethylsilane to Aldehydes
2016 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Multi-State Regulation of the Dihydrogen Phosphate Binding Affinity to a Light- and Heat-Responsive Bis-Urea Receptor
2014 StandoutNobel
Development and Applications of Disulfonimides in Enantioselective Organocatalysis
2015 StandoutNobel
Ability of Serum to Decrease Cellular AcylCoA:Cholesterol Acyl Transferase Activity Predicts Cardiovascular Outcomes
2005
Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
2009
Synthesis of Indeno-Fused Derivatives of Quinolizinium Salts, Imidazo[1,2-a]pyridine, Pyrido[1,2-a]indole, and 4H-Quinolizin-4-one via Benzannulated Enyne−Allenes
2005
Molecular Structure and Physiological Function of Chloride Channels
2002
The Secretory Route of the Leaderless Protein Interleukin 1β Involves Exocytosis of Endolysosome-related Vesicles
1999
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Detection of Calcium Transients inDrosophilaMushroom Body Neurons with Camgaroo Reporters
2003 StandoutNobel
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes
2015 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
IDPi Catalysis
2019 StandoutNobel
Metal–Organic Frameworks in Biomedicine
2011 Standout
Plant Aquaporins: Membrane Channels with Multiple Integrated Functions
2008 Standout
Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages
2007
Tolerogenic Dendritic Cells
2003 StandoutNobel
Catalytic Enantioselective Allylation of Carbonyl Compounds and Imines
2011
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
2009
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
N‐Heterocyclic Carbene‐Catalyzed Annulations of Enals and Ynals with Indolin‐3‐ones: Synthesis of 3,4‐Dihydropyrano[3,2‐b]indol‐2‐ones
2013
High Density Lipoproteins and Arteriosclerosis
2001
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation
2002
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
2004 StandoutScience
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Frédéric Becq being referenced
Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation
2006
Localisation of wild-type and ?F508-CFTR in nasal epithelial cells
2001
Structural basis for specificity and potency of xanthine derivatives as activators of the CFTR chloride channel
1998
Parallel Improvement of Sodium and Chloride Transport Defects by Miglustat (n-Butyldeoxynojyrimicin) in Cystic Fibrosis Epithelial Cells
2008
Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells
2005
Characterization of cAMP dependent CFTR‐chloride channels in human trache gland cells
1993
ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes
1997
Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Channel by β-Adrenergic Agonists and Vasoactive Intestinal Peptide in Rat Smooth Muscle Cells and Its Role in Vasorelaxation
2004
The Cystic Fibrosis Mutation G551D Alters the Non-Michaelis-Menten Behavior of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channel and Abolishes the Inhibitory Genistein Binding Site
2002
Rescue of functional delF508‐CFTR channels in cystic fibrosis epithelial cells by the α‐glucosidase inhibitor miglustat
2006
Cloning and expression of two plasma membrane aquaporins expressed during the ripening of grape berry
2003
Rescue of ΔF508-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) by Curcumin: Involvement of the Keratin 18 Network
2006
Pharmacological therapy for cystic fibrosis: From bench to bedside
2011
Correction of G551D‐CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB‐07
2002
Acute Effects of Adenosine Triphosphates, Cyclic 3′,5′-Adenosine Monophosphates, and Follicle-Stimulating Hormone on Cytosolic Calcium Level in Cultured Immature Rat Sertoli Cells
1999
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Confers Glibenclamide Sensitivity to Outwardly Rectifying Chloride Channel (ORCC) in Hi-5 Insect Cells
1999
cAMP- and Ca2+-independent Activation of Cystic Fibrosis Transmembrane Conductance Regulator Channels by Phenylimidazothiazole Drugs
1996
Stimulation of salivary secretion in vivo by CFTR potentiators in Cftr+/+ and Cftr−/− mice
2007
Structure Elucidation of a Dihydropyranone from Tapinanthus dodoneifolius
2007
Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation
2001
Properties of CFTR activated by the xanthine derivative X-33 in human airway Calu-3 cells
2000
Correction of delF508-CFTR activity with benzo(c)quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells
2001
Interleukin-1β Secretion Is Impaired by Inhibitors of the Atp Binding Cassette Transporter, ABC1
1997
Phosphatase inhibitors activate normal and defective CFTR chloride channels.
1994
Synthesis, SAR, Crystal Structure, and Biological Evaluation of Benzoquinoliziniums as Activators of Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Channels
2004