Standout Papers

Amidation of growth hormone releasing factor (1–29) by serine carboxypeptidase catalysed tran... 1991 2026 2002 2014 30
  1. Amidation of growth hormone releasing factor (1–29) by serine carboxypeptidase catalysed transpeptidation (1991)
    Klaus Breddam, Fred Widmer et al. International journal of peptide & protein research

Citation Impact

Citing Papers

Plant secondary metabolism glycosyltransferases: the emerging functional analysis
2005 Standout
New developments in enzymatic peptide synthesis
1991
Modifying enzyme activity and selectivity by immobilization
2012 Standout
Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature
2010
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
To protect peptide pharmaceuticals against peptidases
2010
Antimicrobial Peptides: An Emerging Category of Therapeutic Agents
2016 Standout
Kinetics and specificity of serine proteases in peptide synthesis catalyzed in organic solvents
1989
Strategy for the Directed Evolution of a Peptide Ligase
1996 StandoutNobel
Recent applications of enzymatic peptide synthesis
1994
Candida albicanspathogenicity mechanisms
2013 Standout
Improving enzymes by using them in organic solvents
2001 StandoutNature
Solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl amino acids
1990 Standout
Advances in the molecular characterization of tryptophan hydroxylase
1998
Substrate preferences of glutamic‐acid‐specific endopeptidases assessed by synthetic Peptide Substrates based on intramolecular fluorescence quenching
1992 StandoutNobel
Semisynthesis of carboxy‐terminal fragments of thermolysin
1990
Targeting virulence: A new paradigm for antifungals
2009
Click Chemistry: 1,2,3‐Triazoles as Pharmacophores
2011 Standout
New Lead Structures in Antifungal Drug Discovery
2011
Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses
2016 Standout
Acetylcholinesterase Inhibitors: Pharmacology and Toxicology
2013 Standout
Sinapoyltransferases in the light of molecular evolution
2009
Biologically active peptides and enzymatic approaches to their production
1996
Phenylpropanoid Biosynthesis
2009 Standout
Regulated overproduction and secretion of yeast carboxypeptidase Y
1990
Antimicrobial activity of [2-(methacryloyloxy)ethyl]trimethylammonium chloride against Candida spp.
2011
Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage—initial study for Myasthenia gravis implications
2010
The Absolute Configuration of Belactin A, a β-Lactone-Containing Serine Carboxypeptidase Inhibitor: Importance of the β-Lactone Structure for Serine Carboxypeptidase Inhibition
1999
The sng2 mutant of Arabidopsis is defective in the gene encoding the serine carboxypeptidase‐like protein sinapoylglucose:choline sinapoyltransferase
2001
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 StandoutNobel
Starburst Dendrimers: Molecular‐Level Control of Size, Shape, Surface Chemistry, Topology, and Flexibility from Atoms to Macroscopic Matter
1990 Standout
Peptide amidation: Production of peptide hormonesin vivo andin vitro
2001
Proline-specific endopeptidases from microbial sources: isolation of an enzyme from a Xanthomonas sp
1992 StandoutNobel
Enzymes as Catalysts in Synthetic Organic Chemistry [New Synthetic Methods (53)]
1985
Molecular and Biotechnological Aspects of Microbial Proteases
1998 Standout
Serine carboxypeptidases. A review
1986
Enzyme in der organischen Synthese
1985
Microbial proteinases
2006
Kinetische Racematspaltung sekundärer Alkohole durch Ruthenium(II)‐katalysierte Transferhydrierung
1997 StandoutNobel
Extensive comparison of the substrate preferences of two subtilisins as determined with peptide substrates which are based on the principle of intramolecular quenching
1992 StandoutNobel
Design by Directed Evolution
1998 StandoutNobel
Serine carboxypeptidase-like acyltransferases
2004
Cloning of the SNG1 Gene of Arabidopsis Reveals a Role for a Serine Carboxypeptidase-like Protein as an Acyltransferase in Secondary Metabolism
2000
Amide bond formation and peptide coupling
2005 Standout
Poly(amino acid)s/polypeptides as potential functional and structural materials
2015
Mechanism and yields in enzyme catalysed equilibrium and kinetically controlled synthesis of β-lactam antibiotics, peptides and other condensation products
1986
Versatile Peptide C-Terminal Functionalization via a Computationally Engineered Peptide Amidase
2016 StandoutNobel
Comparative biochemistry of the proteinases of eucaryotic microorganisms
1982
Tetrahedron report number 203
1986
Triterpene Biosynthesis in Plants
2014 Standout
Natural product and natural product derived drugs in clinical trials
2014 Standout
One‐Step C‐Terminal Deprotection and Activation of Peptides with Peptide Amidase from Stenotrophomonas maltophilia in Neat Organic Solvent
2014 StandoutNobel
Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide.
1993 StandoutNobel
Synthesis, characterization, and biomedical assessment of novel bisimidazole–coumarin conjugates
2021 Standout
Clinical and Microbiological Aspects ofTrichomonas vaginalis
1998 Standout
Binding site for fungal β-lactone hymeglusin on cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase
2004 StandoutNobel
Exploitation of Subtilisin BPN‘ as Catalyst for the Synthesis of Peptides Containing Noncoded Amino Acids, Peptide Mimetics and Peptide Conjugates
1997
Determination ofd-amino acids. I. Hydrolysis of DNP-l-amino acid methyl esters with carboxypeptidase-Y
1984
Kinetic Resolution of Racemic Secondary Alcohols by RuII‐Catalyzed Hydrogen Transfer
1997 StandoutNobel
Determination of C-terminal sequences by digestion with serine carboxypeptidases: The influence of enzyme specificity
1987
The Biomedical Use of Silk: Past, Present, Future
2018 Standout

Works of Fred Widmer being referenced

Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes
2007
Use of enzymes in peptide synthesis
1982
Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes
2009
Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing
2009
Amidation of growth hormone releasing factor (1–29) by serine carboxypeptidase catalysed transpeptidation
1991 StandoutNobel
Amino acid methyl esters as amine components in CPD-Y catalyzed peptide synthesis: Control of side reactions
1983
Carboxypeptidase Y catalyzed transpeptidations and enzymatic peptide synthesis
1980
Influence of the substrate structure on carboxypeptidase Y catalyzed peptide bond formation
1980
In Vitro Antifungal Activities of Inhibitors of Phospholipases from the Fungal Pathogen Cryptococcus neoformans
2004
Correlation of Antifungal Activity with Fungal Phospholipase Inhibition Using a Series of Bisquaternary Ammonium Salts
2005
Enzymatic peptide synthesis. Carboxypeptidase Y catalyzed formation of peptide bonds
1979
Possible side-reactions with diazocarbonyl dipeptide esters as protein modifying reagents
1980
Influence of the structure of amine components on carboxypeptidase Y catalyzed amide bond formation
1981
Carboxypeptidase Y catalyzed C-terminal modification in the B-chain of porcine insulin
1981
Carboxypeptidase Y catalyzed C-terminal modifications of peptides
1981
Partial purification of rabbit hind brain tryptophan hydroxylase by affinity chromatography
1975
Carboxypeptidase Y catalyzed peptide synthesis using amino acid alkyl esters as amine components
1980
Rankless by CCL
2026