Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential
2009
Biochemistry of B Lymphocyte Activation
1993
The Croonian Lecture, 1989 Antibodies: a paradigm for the biology of molecular recognition
1990 Nobel
Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene.
1991 StandoutNobel
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
1998
Maturation of the immune response in germinal centers
1991
Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor
1988 StandoutNobel
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
2001 Standout
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Mechanism and Regulation of Immunoglobulin Isotype Switching
1993
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Induction of Somatic Mutation in a Human B Cell Line In Vitro
1997
Codon‐improved Cre recombinase (iCre) expression in the mouse
2002
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
2014 StandoutNature
Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways
1989
Isolation of cDNA encoding a binding protein specific to 5'-phosphorylated single-stranded DNA with G-rich sequences
1993 StandoutNobel
Man-made antibodies
1991 NatureNobel
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
1994
The Dynamic Nature of the Antibody Repertoire
1988 Nobel
The B-cell antigen receptor complex
1991
Soluble antigen can cause enhanced apoptosis of germinal-centre B cells
1995 Nature
The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response
1997
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
Antibody framework residues affecting the conformation of the hypervariable loops
1992 StandoutNobel
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
2000 StandoutNobel
Developmental and Molecular Regulation of Immunoglobulin Class Switch Recombination
1996
Circular DNA is excised by immunoglobulin class switch recombination
1990 StandoutNobel
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
Immunoglobulin Class Switching: Molecular and Cellular Analysis
1990
Intraclonal generation of antibody mutants in germinal centres
1991 Nature
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell‐dependent antigen
1992
DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally
1990
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
2010 Nature
Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors
1997
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development
1992 StandoutNobel
Id proteins at the cross-road of development and cancer
2001
Degradation of the Id2 developmental regulator: targeting via N-terminal ubiquitination
2004 StandoutNobel
The MyoD family of transcription factors and skeletal myogenesis
1995
Discriminating intrinsic and actigen-selected mutational hotspots in immunoglobulin V genes
1993 Nobel
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
Clonal selection and learning in the antibody system
1996 StandoutNature
Phage antibodies: filamentous phage displaying antibody variable domains
1990 StandoutNatureNobel
Selection of phage antibodies by binding affinity
1992 StandoutNobel
Biological and Medical Significance of Calcium Phosphates
2002 Standout
Locus-specific somatic hypermutation in germinal centre T cells
1994 Nature
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
1996 StandoutNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Making antibody fragments using phage display libraries
1991 StandoutNatureNobel
Temporally and spatially regulated somatic mutagenesis in mice
1998
Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells
1999 StandoutNobel
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation
2000
In vitro selection and evolution of proteins
2001
High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans
2011
GERM-LINE TRANSFORMATION OF MICE
1986
ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis
2000
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance.
1995
A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells.
1988
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus
1984 StandoutNatureNobel
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP.
1986
The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis
1999 Standout
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.
1991
Requirement of the Activation-Induced Deaminase ( AID ) Gene for Immunoglobulin Gene Conversion
2002 Science
Stepwise intraclonal maturation of antibody affinity through somatic hypermutation.
1988
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.
1990
Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles.
1991
A hyperconversion mechanism generates the chicken light chain preimmune repertoire
1987
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora
2002 StandoutScienceNobel
Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches
1991
Epstein–Barr virus transforms precursor B cells even before immunoglobulin gene rearrangements
1984 StandoutNatureNobel
Regulation of Ig Class Secretion by Soluble Products of Certain T‐Cell Lines
1984
Contribution of Receptor Editing to the Antibody Repertoire
2001 Science
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
Directed Ig class switch recombination in activated murine B cells.
1987
Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II
1986 StandoutNatureNobel
Neural Science
2000 StandoutNobel
Enhancers and eukaryotic gene transcription
1985
Degradation of Id proteins by the ubiquitin‐proteasome pathway
1999
Reciprocal chromosome translocation between c-myc and immunoglobulin γ2b genes
1983 Nature
Biased distribution of recombination sites within S regions upon immunoglobulin class switch recombination induced by transforming growth factor beta and lipopolysaccharide.
1992 StandoutNobel
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter
1986 StandoutNatureNobel
Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse.
1989
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses
1987
Immunoglobulin Genes
1983 StandoutNobel
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms
2000
Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells
1991 StandoutNobel
Antigen-driven B cell differentiation in vivo.
1993
Antigen Receptors on B Lymphocytes
1992
An immunoglobulin mutator that targets G.C base pairs.
1996
Mutation Drift and Repertoire Shift in the Maturation of the Immune Response
1987 Nobel
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots.
1993 Nobel
Somatic hypermutation
1995 Nobel
Formation of stable transcription complexes as assayed by analysis of individual templates.
1988
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
1990
Three-dimensional structure determination of an anti-2-phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response.
1990 Nobel
Works of Fred Sablitzky being referenced
The expression pattern ofId4, a novel dominant negative helix-loop-helix protein, is distinct fromId1,1d2andId3
1994
Inducible Site-Directed Recombination in Mouse Embryonic Stem Cells
1996
Cloning and Targeted Deletion of the Mouse Fetuin Gene
1997
A homologue of the human MSS1 gene, a positive modulator of HIV-1 gene expression, is massively expressed in Xenopus oocytes
1995
Adult Hematopoietic Stem and Progenitor Cells Require Either Lyl1 or Scl for Survival
2009
Antibody engineering for the analysis of affinity maturation of an anti-hapten response.
1988
Sequence analysis of non-expressed immunoglobulin heavy chain loci in clonally related, somatically mutated hybridoma cells.
1985
Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface.
1988
Molecular basis of an isogeneic anti-idiotypic response.
1984
The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation
2006
Deletion of Cmu genes in mouse B lymphocytes upon stimulation with LPS.
1983
Stage- and subcellular-specific expression of Id proteins in male germ and Sertoli cells implicates distinctive regulatory roles for Id proteins during meiosis, spermatogenesis, and Sertoli cell function.
1998
Id helix—loop—helix proteins in cell growth and differentiation
1998
Spontaneous Immunoglobulin Class Switching in Myeloma and Hybridoma Cell Lines Differs from Physiological Class Switching
1982
Switch from NP-specific IgG3 to IgG1 in the mouse hybridoma cell line S24/63/63.
1982
Timing, Genetic Requirements and Functional Consequences of Somatic Hypermutation during B‐Cell Development
1987
Somatic mutation and clonal expansion of B cells in an antigen-driven immune response.
1985
V gene rearrangement is required to fully activate the hypermutation mechanism in B cells.
1989
Mutually exclusive expression of two dominant-negative helix-loop-helix (dnHLH) genes, Id4 and Id3, in the developing brain of the mouse suggests distinct regulatory roles of these dnHLH proteins during cellular proliferation and differentiation of the nervous system.
1995
Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant.
1984
V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer.
1993