Standout Papers
Citation Impact
Citing Papers
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
2012 StandoutScience
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses
2010
Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing
2010
Immunomodulatory Function of Interleukin 28B During Primary Infection With Cytomegalovirus
2014 StandoutNobel
Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling
2010
Recognition of herpesviruses by the innate immune system
2011
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
2015 StandoutNobel
Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins
2010
NF-κB signaling in inflammation
2017 Standout
Necroptosis and its role in inflammation
2015 StandoutNature
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
2009
RIG-I-like receptors: their regulation and roles in RNA sensing
2020
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Atopic dermatitis
2015 Standout
ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses
2010
Activation and regulation of the inflammasomes
2013 Standout
Cytosolic Sensing of Viruses
2013
Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing
2014 StandoutNobel
Activation of host pattern recognition receptors by viruses
2010
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Type I interferons in infectious disease
2015 Standout
Tumor vaccination using messenger RNA: prospects of a future therapy
2011
Pattern Recognition Receptors and Inflammation
2010 Standout
Cancer immunotherapy via dendritic cells
2012 Standout
Melioidosis
2012 Standout
Severe Sepsis and Septic Shock
2013 Standout
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
2019 StandoutNobel
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
Pathogen Recognition by the Innate Immune System
2011 Standout
Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response
2020 StandoutNobel
Recognition of viruses by cytoplasmic sensors
2010
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Multiple Interferon Stimulated Genes Synergize with the Zinc Finger Antiviral Protein to Mediate Anti-Alphavirus Activity
2012 StandoutNobel
Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling
2012
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
The trinity of COVID-19: immunity, inflammation and intervention
2020 Standout
Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
2009
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Sterile inflammation: sensing and reacting to damage
2010 Standout
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Regulation of type I interferon responses
2013 Standout
PKR Transduces MDA5-Dependent Signals for Type I IFN Induction
2016
In Vivo Analysis of Aicda Gene Regulation: A Critical Balance between Upstream Enhancers and Intronic Silencers Governs Appropriate Expression
2013 StandoutNobel
Discrimination of cytosolic self and non-self RNA by RIG-I-like receptors
2017
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA
2011
ATP-Dependent Effector-like Functions of RIG-I-like Receptors
2015 StandoutNobel
ATPase‐driven oligomerization of RIG‐I on RNA allows optimal activation of type‐I interferon
2013
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP)
2019 StandoutNobel
RIGorous Detection: Exposing Virus Through RNA Sensing
2010 Science
Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA
2017 StandoutNobel
DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling
2011
Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids
2014
DSRNA and the Innate Antiviral Immune Response
2010
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
2011 StandoutNobel
Recognition of viral nucleic acids in innate immunity
2009
Nucleic Acid Recognition by the Innate Immune System
2011
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
A Virological View of Innate Immune Recognition
2012
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Wound Healing: A Cellular Perspective
2018 Standout
Response of Hepatitis C Virus to Long-Term Passage in the Presence of Alpha Interferon: Multiple Mutations and a Common Phenotype
2013 StandoutNobel
Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis
2011
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20
2018 StandoutNobel
RIG-I and Other RNA Sensors in Antiviral Immunity
2018
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA
2015
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Franziska Hoffmann being referenced
5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
2009