Citation Impact
Citing Papers
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2–dependent mechanisms with implications for psoriasis pathogenesis
2006
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
2007
Keratinocyte Overexpression of IL-17C Promotes Psoriasiform Skin Inflammation
2013
Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis
2010
Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
2009 Standout
The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis
2007
Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines
2016
Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae
2005 StandoutNatureNobel
Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1,which simulates an activated CD40 receptor
1998
A Subpopulation of CD163-Positive Macrophages Is Classically Activated in Psoriasis
2010
Safety and Efficacy of ABT-874, a Fully Human Interleukin 12/23 Monoclonal Antibody, in the Treatment of Moderate to Severe Chronic Plaque Psoriasis
2008
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis
2009
Psoriasis
2009 Standout
Human Keratinocytes' Response to Injury Upregulates CCL20 and Other Genes Linking Innate and Adaptive Immunity
2011
CCR6 is required for IL-23–induced psoriasis-like inflammation in mice
2009
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
1995
IL‐17 and IL‐22 mediate IL‐20 subfamily cytokine production in cultured keratinocytes via increased IL‐22 receptor expression
2009
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
2006
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
The biology and management of non-small cell lung cancer
2018 StandoutNature
Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis
2008
Pathogenesis and therapy of psoriasis
2007 StandoutNature
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
A Human Interleukin-12/23 Monoclonal Antibody for the Treatment of Psoriasis
2007
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
2008
Tildrakizumab versus placebo or etanercept for chronic plaque psoriasis (reSURFACE 1 and reSURFACE 2): results from two randomised controlled, phase 3 trials
2017
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
2008 StandoutNature
Suppression of Molecular Inflammatory Pathways by Toll-Like Receptor 7, 8, and 9 Antagonists in a Model of IL-23-Induced Skin Inflammation
2013
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
1996 StandoutNature
Abundant gene conversion between arms of palindromes in human and ape Y chromosomes
2003 Nature
Psoriasis Is Characterized by Accumulation of Immunostimulatory and Th1/Th17 Cell-Polarizing Myeloid Dendritic Cells
2008
Development, cytokine profile and function of human interleukin 17–producing helper T cells
2007 Standout
Psoriasis
2021 Standout
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
1995
IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis
2012
Genetic Variations in Cytokines and Cytokine Receptors Associated with Psoriasis Found by Genome-Wide Association
2008
Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model
2009
Type I Interferon: Potential Therapeutic Target for Psoriasis?
2008
Genomic Divergences between Humans and Other Hominoids and the Effective Population Size of the Common Ancestor of Humans and Chimpanzees
2001
The pathogenic role of tissue-resident immune cells in psoriasis
2007
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
2005 Nature
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
2004
Activation of the p38 Mitogen-activated Protein Kinase Pathway by Epstein-Barr Virus-encoded Latent Membrane Protein 1 Coregulates Interleukin-6 and Interleukin-8 Production
1999
Psoriasis: emerging therapeutic strategies
2005
Computational Design of an Unnatural Amino Acid Dependent Metalloprotein with Atomic Level Accuracy
2013 StandoutNobel
Mutations in IL36RN/IL1F5 Are Associated with the Severe Episodic Inflammatory Skin Disease Known as Generalized Pustular Psoriasis
2011
Getting under the skin: the immunogenetics of psoriasis
2005
LMP1 structure and signal transduction
2001
Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation
2011
Immunity, Inflammation, and Cancer
2010 Standout
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
IL-23 promotes tumour incidence and growth
2006 Nature
Acne vulgaris
2011 Standout
Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis
2010
Cellular Genomic Maps Help Dissect Pathology in Human Skin Disease
2007
IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis
2017
Inflammation and necrosis promote tumour growth
2004
Taking dendritic cells into medicine
2007 StandoutNatureNobel
The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans
2011
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
2008 Standout
Epstein–Barr virus: 40 years on
2004 Standout
Latent membrane protein 1of Epstein-Barr virus mimics a constitutively active receptor molecule
1997
A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes
2007
Psoriasis: genetic associations and immune system changes
2006
PSORS2 Is Due to Mutations in CARD14
2012
Innate and adaptive immunity and the pathophysiology of psoriasis
2006
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2
1999
New insights of T cells in the pathogenesis of psoriasis
2012
NF-κB and cell-cycle regulation: the cyclin connection
2001
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages
2007 StandoutNobel
Molecular Dissection of Psoriasis: Integrating Genetics and Biology
2009
Signaling to NF-κB
2004 Standout
Ultraviolet B Light Stimulates lnterleukin‐20 Expression by Human Epithelial Keratinocytes
2006
Epstein–Barr virus and oncogenesis: from latent genes to tumours
2003
The Multitasking Organ: Recent Insights into Skin Immune Function
2011
Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and ‘Type 1’ inflammatory gene expression
2004
Oncogenes and cell death
1994
Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk
2012
Antimicrobial peptides in the pathogenesis of psoriasis
2012
Cancer-related inflammation
2008 StandoutNature
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Molecular evolution of FOXP2, a gene involved in speech and language
2002 StandoutNatureNobel
Understanding the IL-23–IL-17 immune pathway
2005
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
1997 StandoutNature
A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis
2004
Anti-cytokine therapies for psoriasis
2011
Skin-Resident T Cells: The Ups and Downs of On Site Immunity
2009
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
2004 StandoutNature
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
2013
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
In Vitro and In Situ Expression of IL-23 by Keratinocytes in Healthy Skin and Psoriasis Lesions: Enhanced Expression in Psoriatic Skin
2006
The Genetic Legacy of Paleolithic Homo sapiens sapiens in Extant Europeans: A Y Chromosome Perspective
2000 StandoutScience
Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
2004
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Structural basis of the action of thermolysin and related zinc peptidases
1988
Immunology of Psoriasis
2014 Standout
Targeting ALK: Precision Medicine Takes on Drug Resistance
2017
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris
2005
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis
2006
TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques
2005
Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
2010
Antisense to the Epstein-Barr Virus (EBV)-Encoded Latent Membrane Protein 1 (LMP-1) Suppresses LMP-1 and Bcl-2 Expression and Promotes Apoptosis in EBV-Immortalized B Cells
1998
Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway
2004
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Intra- and Interspecific Variation in Primate Gene Expression Patterns
2002 StandoutScienceNobel
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Shielding the double-edged sword: negative regulation of the innate immune system
2003
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Mimicry of CD40 Signals by Epstein-Barr Virus LMP1 in B Lymphocyte Responses
1999 Science
Psoriasis
2011
A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis
2018
Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1α, and TNF-α Recapitulates Some Features of Psoriasis
2010
Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients
2005 StandoutNobel
Identification of Cellular Pathways of “Type 1,” Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis
2008
Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution
2012 StandoutNobel
Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe
2009
Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease
2011 Standout
Works of Frank Wang being referenced
IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression
2011
Prominent Production of IL-20 by CD68+/CD11c+ Myeloid-Derived Cells in Psoriasis: Gene Regulation and Cellular Effects
2006
Retinoic acid 4-hydroxylase inducibility and clinical response to isotretinoin in patients with acne
2009
The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B.
1992
Functional constituents of the active site of human neutrophil collagenase
1986
Abstract 5655: AP26113 possesses pan-inhibitory activity versus crizotinib-resistant ALK mutants and oncogenic ROS1 fusions.
2013
Population genetic implications from sequence variation in four Y chromosome genes
2000
Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris
2004
Early tissue responses in psoriasis to the antitumour necrosis factor-α biologic etanercept suggest reduced interleukin-17 receptor expression and signalling
2014
Abstract LB-298: AP26113, a potent ALK inhibitor, overcomes mutations in EML4-ALK that confer resistance to PF-02341066 (PF1066)
2010