Standout Papers

EASL 2017 Clinical Practice Guidelines on the... 2007 2026 2013 2019 3.5k
  1. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection (2017)
    Pietro Lampertico, Kosh Agarwal et al. Journal of Hepatology
  2. Global Perspectives on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis (2018)
    Zobair M. Younossi, Frank Tacke et al. Hepatology
  3. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques (2007)
    Frank Tacke, David Álvarez et al. Journal of Clinical Investigation
  4. Liver macrophages in tissue homeostasis and disease (2017)
    Oliver Krenkel, Frank Tacke Nature reviews. Immunology
  5. Macrophage heterogeneity in liver injury and fibrosis (2014)
    Frank Tacke, Henning W. Zimmermann Journal of Hepatology
  6. Immunology in the liver — from homeostasis to disease (2016)
    Felix Heymann, Frank Tacke Nature Reviews Gastroenterology & Hepatology
  7. Targeting hepatic macrophages to treat liver diseases (2017)
    Frank Tacke Journal of Hepatology
  8. Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer (2019)
    Jakob Nikolas Kather, Alexander T. Pearson et al. Nature Medicine
  9. Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis (2010)
    Christoph Roderburg, Kira Bettermann et al. Hepatology
  10. Roles for Chemokines in Liver Disease (2014)
    Fabio Marra, Frank Tacke Gastroenterology
  11. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis # (2009)
    Karlin Raja Karlmark, Ralf Weiskirchen et al. Hepatology
  12. Langerhans cells arise from monocytes in vivo (2006)
    Florent Ginhoux, Frank Tacke et al. Nature Immunology
  13. Comparison of gene expression profiles between human and mouse monocyte subsets (2009)
    Molly A. Ingersoll, Rainer Spanbroek et al. Blood
  14. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts (2006)
    Jordi Ochando, Chiho Homma et al. Nature Immunology
  15. Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury (2011)
    Christer Baeck, Alexander Wehr et al. Gut
  16. Liver — guardian, modifier and target of sepsis (2016)
    Pavel Strnad, Frank Tacke et al. Nature Reviews Gastroenterology & Hepatology
  17. Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities (2020)
    Yankai Wen, Joeri Lambrecht et al. Cellular and Molecular Immunology
  18. EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD) (2024)
    Frank Tacke, Paul Horn et al. Journal of Hepatology
  19. Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications (2018)
    Ralf Weiskirchen, Sabine Weiskirchen et al. Molecular Aspects of Medicine
  20. Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies (2016)
    Cynthia Ju, Frank Tacke Cellular and Molecular Immunology
  21. Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis (2017)
    Oliver Krenkel, Tobias Puengel et al. Hepatology
  22. Hepatic inflammatory responses in liver fibrosis (2023)
    Linda Hammerich, Frank Tacke Nature Reviews Gastroenterology & Hepatology
  23. Global epidemiology of cirrhosis — aetiology, trends and predictions (2023)
    Daniel Q. Huang, Norah A. Terrault et al. Nature Reviews Gastroenterology & Hepatology
  24. Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease – novel insights into cellular communication circuits (2022)
    Moritz Peiseler, Robert F. Schwabe et al. Journal of Hepatology
  25. Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study (2020)
    Vlad Ratziu, Arun J. Sanyal et al. Hepatology
  26. Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors (2020)
    Sven Francque, Gyöngyi Szabó et al. Nature Reviews Gastroenterology & Hepatology
  27. Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages☆ (2020)
    Sander Lefere, Tobias Puengel et al. Journal of Hepatology
  28. An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH (2023)
    Frank Tacke, Tobias Puengel et al. Journal of Hepatology
  29. EASL-EASD-EASO Clinical Practice Guidelines on the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (2024)
    Frank Tacke, Paul Horn et al. Obesity Facts
  30. Metabolic reprogramming in liver fibrosis (2024)
    Paul Horn, Frank Tacke Cell Metabolism
  31. Cenicriviroc Lacked Efficacy to Treat Liver Fibrosis in Nonalcoholic Steatohepatitis: AURORA Phase III Randomized Study (2023)
    Quentin M. Anstee, Brent A. Neuschwander‐Tetri et al. Clinical Gastroenterology and Hepatology
  32. EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD): Executive Summary (2024)
    Frank Tacke, Paul Horn et al. Diabetologia
  33. Acquisition of epithelial plasticity in human chronic liver disease (2024)
    Christopher Gribben, Vasileios Galanakis et al. Nature

Immediate Impact

12 by Nobel laureates 21 from Science/Nature 147 standout
Sub-graph 1 of 18

Citing Papers

Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis
2025 Standout
Steatotic liver disease
2024 Standout
25 intermediate papers

Works of Frank Tacke being referenced

EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)
2024 Standout
Global epidemiology of cirrhosis — aetiology, trends and predictions
2023 Standout
and 21 more

Author Peers

Author Last Decade Papers Cites
Frank Tacke 21618 15955 6060 11216 695 43.6k
Christian Trautwein 14942 12695 5131 6767 700 35.2k
David A. Brenner 26184 21617 8883 6973 507 58.1k
David E. Kleiner 31134 17152 7096 4177 510 49.1k
Scott L. Friedman 31616 30129 9374 5300 431 60.2k
Michael P. Manns 40953 45849 10951 10086 1.3k 75.1k
Peter R. Galle 15648 18671 10714 10050 1.2k 53.9k
M. Eric Gershwin 11626 12795 6938 9976 868 38.4k
Jacob George 16021 8901 3093 4726 589 29.3k
Herbert Tilg 17363 4777 5585 5297 442 38.5k
Kazuaki Chayama 15457 14718 10433 2929 1.4k 44.3k

All Works

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2026