Citation Impact
Citing Papers
Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
2016
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
2010 StandoutScience
Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis
2016
Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis
2019
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Contact-ID, a tool for profiling organelle contact sites, reveals regulatory proteins of mitochondrial-associated membrane formation
2020
MOMP, cell suicide as a BCL-2 family business
2017
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Human high-altitude adaptation: forward genetics meets the HIF pathway
2014
Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy
2014
Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells
2018
Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size
2013
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
2019 StandoutNobel
Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis
2018
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
2010
Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming
2013
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages
2018
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)
2017
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Structural Model of Active Bax at the Membrane
2014
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Shedding Light on Apoptosis at Subcellular Membranes
2012
BID-induced structural changes in BAK promote apoptosis
2013
mTOR signaling: At the crossroads of plasticity, memory and disease
2009
The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment
2011
Hypoxia and Inflammation
2011 Standout
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
2019 StandoutNobel
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
2012 StandoutNobel
Mitochondria—Judges and Executioners of Cell Death Sentences
2016
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
2019
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis
2016
Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation
2014
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
2011
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Targeting apoptosis in cancer therapy
2020 Standout
An interconnected hierarchical model of cell death regulation by the BCL-2 family
2015
A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria
2011
Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets
2008
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
2015 StandoutNobel
Role and regulation of prolyl hydroxylase domain proteins
2008
HIF–prolyl hydroxylases and cardiovascular diseases
2012
Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics
2011
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
2006
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth
2010
A fate worse than death: apoptosis as an oncogenic process
2016
Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
2013
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
2012
Small-molecule allosteric inhibitors of BAX
2019
Mitochondria as multifaceted regulators of cell death
2019 Standout
Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity
2014
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
2015
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
2012
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Mitochondrial origins of fractional control in regulated cell death
2019
Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
2016
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
2013 StandoutNobel
Recent advances into the understanding of mitochondrial fission
2012
Mechanisms of Action of Bcl-2 Family Proteins
2013
Mst1 Promotes Cardiac Myocyte Apoptosis through Phosphorylation and Inhibition of Bcl-xL
2014
Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance
2016
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Replication of hepatitis C virus
2007 StandoutNobel
Metabolic regulation of mitochondrial dynamics
2016
Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak
2017
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells
2014 StandoutNobel
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
How Mitochondrial Dynamism Orchestrates Mitophagy
2015
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential
2011
Hepatitis C Virus Co-Opts Ras-GTPase-Activating Protein-Binding Protein 1 for Its Genome Replication
2011 StandoutNobel
Metabolic control of cell death
2014 Science
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
2011
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation
2017 StandoutNobel
Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health
2011
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
2015 StandoutNobel
Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function
2015
SCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA ReplicationIn Vitro
2009
Determinants and Functions of Mitochondrial Behavior
2014
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Works of Frank Edlich being referenced
Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes
2016
Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML
2017
Mito-priming as a method to engineer Bcl-2 addiction
2016
Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38
2009
The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation
2016
The C-terminal helix of Bcl-xL mediates Bax retrotranslocation from the mitochondria
2012
The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes
2011
Bcl‐2 regulator FKBP38 is activated by Ca2+/calmodulin
2005
Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
2011
Pharmacological Targeting of Catalyzed Protein Folding: The Example of Peptide Bond cis/trans Isomerases
2005
The Peptidyl Prolyl cis/trans Isomerase FKBP38 Determines Hypoxia-Inducible Transcription Factor Prolyl-4-Hydroxylase PHD2 Protein Stability
2007
Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA
2012
Parkin promotes proteasomal degradation of misregulated BAX
2017
Differential retrotranslocation of mitochondrial Bax and Bak
2014
Comparative Analysis of Calcineurin Inhibition by Complexes of Immunosuppressive Drugs with Human FK506 Binding Proteins
2006