Citation Impact
Citing Papers
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Cold-Activated Brown Adipose Tissue in Healthy Men
2009 Standout
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells
2003
Medicinal strategies in the treatment of obesity
2000 Nature
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase
1999
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Uncoupling Protein-3 Expression in Rodent Skeletal Muscle Is Modulated by Food Intake but Not by Changes in Environmental Temperature
1998
Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes
2001
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Autophagy regulates lipid metabolism
2009 StandoutNature
Obesity Induces Expression of Uncoupling Protein-2 in Hepatocytes and Promotes Liver ATP Depletion
1999
Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action
2003
Nonalcoholic Fatty Liver Disease
2002 Standout
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
2004 Standout
Genetic and environmental determinants of non‐insulin‐dependent diabetes mellitus (NIDDM)
1992
Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery
2002 Standout
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
1999 Standout
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Functional Organization of the Human Uncoupling Protein-2 Gene, and Juxtaposition to the Uncoupling Protein-3 Gene
1999
Lack of Obesity and Normal Response to Fasting and Thyroid Hormone in Mice Lacking Uncoupling Protein-3
2000
Hundreds of ankyrin‐like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally?
1993
Energy Metabolism in Uncoupling Protein 3 Gene Knockout Mice
2000
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
1998 Standout
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Mitochondria: In Sickness and in Health
2012 Standout
Functional Brown Adipose Tissue in Healthy Adults
2009 Standout
The mitochondrial uncoupling-protein homologues
2005
PPARs and the complex journey to obesity
2004
Direct Binding of Activated c-Src to the β3-Adrenergic Receptor Is Required for MAP Kinase Activation
2000 StandoutNobel
Diabetes epidemiology as a tool to trigger diabetes research and care
1999
Role of the β3-Adrenergic Receptor and/or a Putative β4-Adrenergic Receptor on the Expression of Uncoupling Proteins and Peroxisome Proliferator-Activated Receptor-γ Coactivator-1
1999
Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin
1997
Developmental Origins of the Metabolic Syndrome: Prediction, Plasticity, and Programming
2005
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
2000 Standout
Towards a molecular understanding of adaptive thermogenesis
2000 Nature
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.
1998
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
2012 Standout
Global and societal implications of the diabetes epidemic
2001 StandoutNature
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Uncoupling: new approaches to an old problem of bioenergetics
1998
Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance
2000
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Striking sequence similarity over almost 100 kilobases of human and mouse T–cell receptor DNA
1994
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia
1996
Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2
1999
The hormone resistin links obesity to diabetes
2001 StandoutNature
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
2002 StandoutNature
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Obesity and the Regulation of Energy Balance
2001 Standout
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Genetics of Type 2 diabetes
2005
The active conformation of human glucokinase is not altered by allosteric activators
2011
Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle among Subjects with Impaired Glucose Tolerance
2001 Standout
Insulin Resistance and Insulin Secretory Dysfunction as Precursors of Non-Insulin-Dependent Diabetes Mellitus: Prospective Studies of Pima Indians
1993
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Mitochondrial Uncoupling: Role of Uncoupling Protein Anion Carriers and Relationship to Thermogenesis and Weight Control “The Benefits of Losing Control”
1999
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
2002 StandoutScienceNobel
GENETICS OF NON-INSULIN-DEPENDENT (TYPE-II) DIABETES MELLITUS
1996
A Common Polymorphism in the Promoter of UCP2 Contributes to the Variation in Insulin Secretion in Glucose-Tolerant Subjects
2003
Genomic organization of HLA-DMA and HLA-DMB. Comparison of the gene organization of all six class II families in the human major histocompatibility complex.
1994
Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
2003 Standout
One-megabase sequence analysis of the human immunoglobulin lambda gene locus.
1997
Genomics and human disease—variations on variation
1998 StandoutNobel
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.
2000
Comparative sequence analysis of the human and pufferfish Huntington's disease genes
1995 StandoutNobel
Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy
1999 StandoutNobel
Insulin secretion and differential gene expression in glucose-responsive and -unresponsive MIN6 sublines
2000
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Mitochondrial Uncoupling Proteins in Energy Expenditure
2000
Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.
2003
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Variations on a Theme: Cataloging Human DNA Sequence Variation
1997 Science
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Putting the genes for type II diabetes on the map
2001
Preventing Non-Insulin-Dependent Diabetes
1995
The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
1998 StandoutNobel
Peroxisome Proliferator-Activated Receptors γ and α Mediate in Vivo Regulation of Uncoupling Protein (UCP-1, UCP-2, UCP-3) Gene Expression
1998
The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP
2000
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
The Structure of Haplotype Blocks in the Human Genome
2002 StandoutScience
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin
2002 Standout
Works of François Iris being referenced
Dense Alu clustering and a potential new member of the NFκB family within a 90 kilobase HLA Class III segment
1993
Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus
1992 Nature
Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human Thermogenesis
1997