Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate
2015 StandoutNobel
Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α
2009 Science
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
2010
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
2010
Cancer-Specific High-Throughput Annotation of Somatic Mutations: Computational Prediction of Driver Missense Mutations
2009
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1
2010
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis
2010
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Cancer Cell Metabolism
2011
Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma
2012
IDH1andIDH2Mutations in Gliomas
2009 Standout
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice
2002
Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis
2016
MYC on the Path to Cancer
2012 Standout
Neat1 is a p53-inducible lincRNA essential for transformation suppression
2017
A view on drug resistance in cancer
2019 StandoutNature
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms
2010
IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
2011
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cancer-associated IDH mutations: biomarker and therapeutic opportunities
2010
Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ
2013 Standout
The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization
2012
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas
2009 Standout
Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers
2009
Cell-surface cathepsin B: Understanding its functional significance
2003
IDH mutations in glioma and acute myeloid leukemia
2010
Imaging in the era of molecular oncology
2008 StandoutNature
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
2014
Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry
2013
Relationship between Tumor Enhancement, Edema,IDH1Mutational Status,MGMTPromoter Methylation, and Survival in Glioblastoma
2012
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation
2012
Monoclonal antibody specific for IDH1 R132H mutation
2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Genetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor
2013
Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells
2012
Regulation of cancer cell metabolism
2011 Standout
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Dendritic cells in cancer immunotherapy
2010
Collaboration of 3D context and extracellular matrix in the development of glioma stemness in a 3D model
2015
Malignant Gliomas in Adults
2008 Standout
IDH1 mutation of gliomas with long-term survival analysis
2012
Cancer immunotherapy comes of age
2011 StandoutNature
Differential effects of AKT1(p.E17K) expression on human mammary luminal epithelial and myoepithelial cells
2012
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
2010
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
2011 Nature
TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations: Figure 1
2011
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Characterization of R132H Mutation‐specific IDH1 Antibody Binding in Brain Tumors
2009
Primary brain tumours in adults
2012 Standout
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?
2018
Histone 3 Lysine 9 Trimethylation Is Differentially Associated With Isocitrate Dehydrogenase Mutations in Oligodendrogliomas and High-Grade Astrocytomas
2013
Identification of additional IDH mutations associated with oncometabolite R(−)-2-hydroxyglutarate production
2011
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Mutations in GNA11 in Uveal Melanoma
2010 Standout
2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations
2011
Histone lysine methylation and demethylation pathways in cancer
2010
IDH1andIDH2Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia WithNPM1Mutation WithoutFLT3Internal Tandem Duplication
2010
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Clues from cell metabolism
2010 StandoutNatureNobel
Detection of 2-Hydroxyglutarate in IDH -Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy
2012
Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications
2019 Standout
Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism
2010
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
2009 Standout
Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value
2010
Metabolic reprogramming and cancer progression
2020 StandoutScience
Isocitrate Dehydrogenase Mutations Are Rare in Pheochromocytomas and Paragangliomas
2009
Cancer Genome Landscapes
2013 StandoutScience
Activatable Photosensitizers for Imaging and Therapy
2010 Standout
Eph Receptors and Ephrin Ligands: Important Players in Angiogenesis and Tumor Angiogenesis
2010
Frequent Mutation of Isocitrate Dehydrogenase(IDH)1andIDH2in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping
2011
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
2010
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma
2012
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Works of Fonnet E. Bleeker being referenced
Novel Somatic and Germline Mutations in Cancer Candidate Genes in Glioblastoma, Melanoma, and Pancreatic Carcinoma
2007
IDH1/2 Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors
2018
Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
2009
Absence of AKT1 Mutations in Glioblastoma
2009
Molecular profiling of the âplexinomeâ in melanoma and pancreatic cancer
2009
Mutational profiling of cancer candidate genes in glioblastoma, melanoma and pancreatic carcinoma reveals a snapshot of their genomic landscapes
2008
IDH1mutations at residue p.R132 (IDH1R132) occur frequently in high-grade gliomas but not in other solid tumors
2009
Segregation of non-p.R132H mutations inIDH1in distinct molecular subtypes of glioma
2010
Mutational Profile of GNAQQ209 in Human Tumors
2009
The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
2010
Differential Activity of NADPH-Producing Dehydrogenases Renders Rodents Unsuitable Models to Study IDH1R132 Mutation Effects in Human Glioblastoma
2011
Comparative Localization of Cathepsin B Protein and Activity in Colorectal Cancer
2000