Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures
2019
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
The Protein-Folding Problem, 50 Years On
2012 Science
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Design of symmetric TIM barrel proteins from first principles
2015
Computational Design of a Protein-Based Enzyme Inhibitor
2013 StandoutNobel
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
2014
An Integrated Framework Advancing Membrane Protein Modeling and Design
2015
Computational Enzyme Design
2013 StandoutNobel
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Efficient sampling of protein conformational space using fast loop building and batch minimization on highly parallel computers
2012 StandoutNobel
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
Protein folding and de novo protein design for biotechnological applications
2013
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Crystal structure of a monomeric retroviral protease solved by protein folding game players
2011 StandoutNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering
2011 StandoutNobel
Role of backbone strain in de novo design of complex α/β protein structures
2021 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Self-assembling protein nanoparticles in the design of vaccines
2015
Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
2021 StandoutNobel
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
2017 StandoutNobel
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
Emerging themes in the computational design of novel enzymes and protein–protein interfaces
2012
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
De novo enzymes by computational design
2013
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Computational enzyme design: Transitioning from catalytic proteins to enzymes
2014
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Protein sequence design with a learned potential
2022
Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement
2013 StandoutNobel
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coli’s Periplasm
2018
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Computational Design of an α-Gliadin Peptidase
2012 StandoutNobel
Relaxation of backbone bond geometry improves protein energy landscape modeling
2013 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Design of Protein Catalysts
2013
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
Directed Evolution of Protein Catalysts
2018
Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair
2012
The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
2017 StandoutNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Foldit Standalone: a video game-derived protein structure manipulation interface using Rosetta
2017 StandoutNobel
Computational design of a pH-sensitive IgG binding protein
2013 StandoutNobel
Combined Covalent-Electrostatic Model of Hydrogen Bonding Improves Structure Prediction with Rosetta
2015 StandoutNobel
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design
2011 StandoutNobel
Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions
2015 StandoutNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Works of Foldit Players being referenced
Increased Diels-Alderase activity through backbone remodeling guided by Foldit players
2012 StandoutNobel
Predicting protein structures with a multiplayer online game
2010 StandoutNatureNobel
Algorithm discovery by protein folding game players
2011 StandoutNobel