Standout Papers
Citation Impact
Citing Papers
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation
2005 Science
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Trif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling
2006
Identification of the haematopoietic stem cell niche and control of the niche size
2003 StandoutNature
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
The new framework for understanding placental mammal evolution
2009
GDF5 Coordinates Bone and Joint Formation during Digit Development
1999
Promoter structure of mouse RANKL/TRANCE/OPGL/ODF gene
1999
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Peptide Epitope Identification by Affinity Selection on Bacteriophage MS2 Virus-Like Particles
2011
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Expression of the Osteoblast Differentiation Factor RUNX2 (Cbfa1/AML3/Pebp2αA) Is Inhibited by Tumor Necrosis Factor-α
2002
Association of a RUNX2 Promoter Polymorphism with Bone Mineral Density in Postmenopausal Korean Women
2009
Homing of antibody secreting cells
2003
Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation
1998
TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation
2001
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Expression of the PEBP2αA/AML3/CBFA1 Gene is Regulated by BMP4/7 Heterodimer and Its Overexpression Suppresses Type I Collagen and Osteocalcin Gene Expression in Osteoblastic and Nonosteoblastic Mesenchymal Cells
1998
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
The genetic transformation of bone biology
1999
Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases
2009
Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis
2014 Standout
MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes
1998 Standout
Promoter 2 -1025 T/C Polymorphism in the RUNX2 Gene Is Associated with Femoral Neck BMD in Spanish Postmenopausal Women
2007
Origins and functions of phagocytes in the embryo
2000
TCF1 in T cell immunity: a broadened frontier
2021
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation
1997 Standout
Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice
2001
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
2002
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Developmental regulation of the growth plate
2003 StandoutNature
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
1999 Standout
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Growth Regulatory Factors and Bone
2001
Global cancer statistics
2011 Standout
Smad and AML Proteins Synergistically Confer Transforming Growth Factor β1 Responsiveness to Human Germ-line IgA Genes
2000
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Integrative analysis of RUNX1 downstream pathways and target genes
2008
Novel Roles for MLH3 Deficiency and TLE6-Like Amplification in DNA Mismatch Repair-Deficient Gastrointestinal Tumorigenesis and Progression
2008 StandoutNobel
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
2002 Standout
The Transcription Factors L-Sox5 and Sox6 Are Essential for Cartilage Formation
2001
Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates
2009 Standout
The Missing Bone
1997
MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover
1999
Interaction and Functional Cooperation of PEBP2/CBF with Smads
1999
Building strong bones: molecular regulation of the osteoblast lineage
2011
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Cleidocranial dysplasia: oral features and genetic analysis of 11 patients
2011
Osteoclast differentiation and activation
2003 StandoutNature
Maturational disturbance of chondrocytes inCbfa1-deficient mice
1999
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Eicosanoids and cancer
2010 Standout
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
2002
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Mechanisms of Bone Metastasis
2004 Standout
Regulation of chondrocyte differentiation by Cbfa1
1999
How cells read TGF-β signals
2000 Standout
The Hallmarks of Aging
2013 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia
1997
Sox9 Directs Hypertrophic Maturation and Blocks Osteoblast Differentiation of Growth Plate Chondrocytes
2012
Genetic control of skeletal development
2001
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
2007 Standout
Integrins
2002 Standout
Cancer-related inflammation: Common themes and therapeutic opportunities
2011
Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
2010
Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development
2002
Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor
1998
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
2009 Standout
Genomic Promoter Occupancy of Runt-related Transcription Factor RUNX2 in Osteosarcoma Cells Identifies Genes Involved in Cell Adhesion and Motility
2011
Mammalian runt‐domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia
1999
ASCO 2006 Update of Recommendations for the Use of Tumor Markers in Gastrointestinal Cancer
2006
Functional Consequences of Integrin Gene Mutations in Mice
2001
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
The Osteoblast: A Sophisticated Fibroblast under Central Surveillance
2000 Science
Cleidocranial dysplasia: clinical and molecular genetics
1999
Cloning of a 2.5 kb Murine Bone Sialoprotein Promoter Fragment and Functional Analysis of Putative Osf2 Binding Sites
1999
Conditional Ablation of the Osteoblast Lineage in Col2.3Δtk Transgenic Mice
2001
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Differential Expression Patterns of Runx2 Isoforms in Cranial Suture Morphogenesis
2001
Structure and Function of Toll Receptors and Their Ligands
2007
Bone Resorption by Osteoclasts
2000 StandoutScience
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion
2005
Conditional Vascular Cell Adhesion Molecule 1 Deletion in Mice
2001
Bone Development
2000
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
2004
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
Dose-Dependent Effects of Runx2 on Bone Development
2009
Collagenase 3 Is a Target of Cbfa1, a Transcription Factor of the runt Gene Family Involved in Bone Formation
1999
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Association of Functionally Different RUNX2 P2 Promoter Alleles With BMD
2006
Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia
1999
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis
2009
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
2004
Differential Roles for Bone Morphogenetic Protein (BMP) Receptor Type IB and IA in Differentiation and Specification of Mesenchymal Precursor Cells to Osteoblast and Adipocyte Lineages
1998
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
2009 Standout
CD18 Is Required for Optimal Development and Function of CD4+CD25+ T Regulatory Cells
2005
Global cancer statistics, 2012
2015 Standout
Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans
2009
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Skeletal Malformations Caused by Overexpression of Cbfa1 or Its Dominant Negative Form in Chondrocytes
2001
Adhesive mechanisms governing interferon-producing cell recruitment into lymph nodes
2005
A Coordinated Change in Chemokine Responsiveness Guides Plasma Cell Movements
2001
Works of Florian Otto being referenced
Upstream and downstream targets of RUNX proteins
2003
Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development
1997 Standout
Gene deregulation in gastric cancer
2005
Control of RUNX2 isoform expression: The role of promoters and enhancers
2005
Mutations in theRUNX2 gene in patients with cleidocranial dysplasia
2002
Mammalian Groucho homologs: Redundancy or specificity?
2005
Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis
2001
Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement
2009
Runx3 knockouts and stomach cancer
2003
The epitope recognized by rituximab
2006
Lymphocyte Migration in Lymphocyte Function-associated Antigen (LFA)-1–deficient Mice
1999
Protein Kinase Cϵ Is Required for Macrophage Activation and Defense Against Bacterial Infection
2001
Adjuvant radiochemotherapy of stage II and III rectal adenocarcinoma: role of CEA and CA 19-9.
2005
Identification of Novel Target Genes of the Bone-Specific Transcription Factor Runx2
2004