Citation Impact
Citing Papers
A Novel Functional Human Eukaryotic Translation Initiation Factor 4G
1998
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
The structure of the 80S ribosome from Trypanosoma cruzi reveals unique rRNA components
2005 StandoutNobel
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer
2003
Translation factors as effectors of cell growth and tumorigenesis
1993
Expression of the Aflatoxin B1-8,9-Epoxide-Metabolizing Murine Glutathione S-Transferase A3 Subunit Is Regulated by the Nrf2 Transcription Factor through an Antioxidant Response Element
2003
Human Eukaryotic Initiation Factor 4G (eIF4G) Protein Binds to eIF3c, -d, and -e to Promote mRNA Recruitment to the Ribosome
2013
MicroRNAs
2004 Standout
A new translational regulator with homology to eukaryotic translation initiation factor 4G
1997
Binding of protein synthesis initiation factor 4E to oligoribonucleotides: effects of cap accessibility and secondary structure
1992
Overexpression of a DEAD Box Protein (DDX1) in Neuroblastoma and Retinoblastoma Cell Lines
1998
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3
1992
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
A conserved secondary structure for telomerase RNA
1991 StandoutNobel
Insulin-like growth factors and neoplasia
2004
Cloning and Characterization of 4EHP, a Novel Mammalian eIF4E-related Cap-binding Protein
1998
Vitamin D Deficiency
2007 Standout
eIF4G Dramatically Enhances the Binding of eIF4E to the mRNA 5′-Cap Structure
1997
RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
1998
Phosphorylation of elF‐4E and initiation of protein synthesis in P19 embryonal carcinoma cells
1995
Requirements for U2 snRNP addition to yeast pre-mRNA
1992 StandoutNobel
Cap-Independent Translation and Internal Initiation of Translation in Eukaryotic Cellular mRNA Molecules
1995
Mapping of Functional Domains in Eukaryotic Protein Synthesis Initiation Factor 4G (eIF4G) with Picornaviral Proteases
1995
Genes Expressed in Neurons of Adult Male Drosophila
1997 StandoutNobel
Purification and Characterization of a New Eukaryotic Protein Translation Factor
1998
The Hallmarks of Cancer
2000 Standout
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa
2006
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
‘Ribozoomin’ – Translation Initiation from the Perspective of the Ribosome-bound Eukaryotic Initiation Factors (eIFs)
2012
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study
2007
Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes
1997
Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation
1998 Nature
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap
1990 Nature
Translation Eukaryotic Initiation Factor 4G Recognizes a Specific Structural Element within the Internal Ribosome Entry Site of Encephalomyocarditis Virus RNA
1998
DEAD-box proteins: the driving forces behind RNA metabolism
2004
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection
2002
Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20
1998
A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E
1997
IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F
1998
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Participation of initiation factors in the recruitment of mRNA to ribosomes
1994
The ATP requirement for initiation of eukaryotic translation varies according to the mRNA species
1991
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
An3 protein encoded by a localized maternal mRNA in Xenopus laevis is an ATPase with substrate-specific RNA helicase activity
1997
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
Cryo-EM Visualization of a Viral Internal Ribosome Entry Site Bound to Human Ribosomes
2004 StandoutNobel
Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap‐complex function
2002
The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
1998
The maleless protein associates with the X chromosome to regulate dosage compensation in drosophila
1991
Initiation of Protein Synthesis in Eukaryotic Cells
1996
Role for a bidentate ribonuclease in the initiation step of RNA interference
2001 StandoutNature
Plasmid cDNA-directed protein synthesis in a coupled eukaryoticin vitrotranscription-translation system
1992 StandoutNobel
A Reevaluation of the Cap-binding Protein, eIF4E, as a Rate-limiting Factor for Initiation of Translation in Reticulocyte Lysate
1996
Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study
2006 Standout
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro
1998
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions
2001 StandoutNobel
The DEAD Box Protein eIF4A. 2. A Cycle of Nucleotide and RNA-Dependent Conformational Changes
1998
A new yeast translation initiation factor suppresses a mutation in the eIF-4A RNA helicase.
1993
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
NAB2: a Yeast Nuclear Polyadenylated RNA-Binding Protein Essential for Cell Viability
1993
Hypoxia enhances phosphorylation of eukaryotic initiation factor 4A in maize root tips.
1991
RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria
1993
eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation
1999 Standout
Cellular Actions of the Insulin-Like Growth Factor Binding Proteins
2002
Human Eukaryotic Translation Initiation Factor 4G (eIF4G) Possesses Two Separate and Independent Binding Sites for eIF4A
1997
Epidermal induction and inhibition of neural fate by translation initiation factor 4AIII
1997
Insulin induction of ornithine decarboxylase. Importance of mRNA secondary structure and phosphorylation of eucaryotic initiation factors eIF-4B and eIF-4E
1991
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Mechanism and regulation of eukaryotic protein synthesis
1992
Cleavage of p220 by Purified Poliovirus 2Apro in Cell-Free Systems: Effects on Translation of Capped and Uncapped mRNAs
1997
Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif.
1990
A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export.
1996
A general two-metal-ion mechanism for catalytic RNA.
1993 StandoutNobel
Rapamycin and Wortmannin Enhance Replication of a Defective Encephalomyocarditis Virus
1998
Multiple mRNAs encode the murine translation initiation factor eIF-4E
1991
Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E.
1995
A second hepatitis C virus-encoded proteinase.
1993 StandoutNobel
A Region Rich in Aspartic Acid, Arginine, Tyrosine, and Glycine (DRYG) Mediates Eukaryotic Initiation Factor 4B (eIF4B) Self-Association and Interaction with eIF3
1996
Genetic Polymorphisms Involved in Insulin-like Growth Factor (IGF) Pathway in Relation to Mammographic Breast Density and IGF Levels
2008
The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)
1996
Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
1998
Structural interaction between the nuclear pore complex and a specific translocating RNP particle.
1995
Selective translation initiation by ribosome jumping in adenovirus-infected and heat-shocked cells.
1996
Identification and characterization of cap-binding proteins from yeast
1989
Canonical Eukaryotic Initiation Factors Determine Initiation of Translation by Internal Ribosomal Entry
1996
The Molecular Mechanics of Eukaryotic Translation
2004
mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm
1997 StandoutNobel
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
1991 Standout
Translational Potentiation of Messenger RNA with Secondary Structure in Xenopus
1991 Science
Genome-wide comprehensive analysis of human helicases
2011
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Eukaryotic Initiation Factor 4GII (eIF4GII), but Not eIF4GI, Cleavage Correlates with Inhibition of Host Cell Protein Synthesis after Human Rhinovirus Infection
1999
D‐E‐A‐D protein family of putative RNA helicases
1992
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs.
1992
Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities
1994
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.
1997 StandoutNobel
The Saccharomyces cerevisiae translation initiation factor Tif3 and its mammalian homologue, eIF-4B, have RNA annealing activity.
1995
Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems
1999
Two structural domains of initiation factor eIF-4B are involved in binding to RNA.
1994
Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.
1996
Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation.
1992
Mutational analysis of the hepatitis C virus RNA helicase
1997
A Saccharomyces cerevisiae homologue of mammalian translation initiation factor 4B contributes to RNA helicase activity.
1993
Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.
1994
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
1996
Interactions of the eIF-4F subunits in the yeast Saccharomyces cerevisiae.
1992
Functional Dissection of Eukaryotic Initiation Factor 4F: the 4A Subunit and the Central Domain of the 4G Subunit Are Sufficient To Mediate Internal Entry of 43S Preinitiation Complexes
1996
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b.
1994 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Angiotensin II induces phosphorylation of eukaryotic protein synthesis initiation factor 4E in vascular smooth muscle cells.
1994
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A.
1993
Noncalcemic Actions of Vitamin D Receptor Ligands
2005
The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase
1996
TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.
1993
Opposing actions of prostaglandins and oxytocin determine the onset of murine labor
1998
Regulation of translation initiation factor gene expression during human T cell activation.
1992
Helicases and RNA unwinding in translation
1993
Genome-wide comprehensive analysis of human helicases.
2011
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The target of rapamycin (TOR) proteins
2001
The IGF axis and programmed cell death
1999
La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate
1993
Familial Invasive Breast Cancers: Worse Outcome Related to BRCA1 Mutations
2000
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
Requirement of the DEAD-Box Protein Ded1p for Messenger RNA Translation
1997 Science
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae
1997
Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein
1991 Science
Phosphorylation of eukaryotic translation initiation factor 4E is increased in Src-transformed cell lines.
1991
RNA unwinding in translation: assembly of helicase complex intermediates comprising eukaryotic initiation factors eIF-4F and eIF-4B.
1991
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA
2015
Alternative mechanisms of initiating translation of mammalian mRNAs
2005
Works of Florence Rozen being referenced
Antiproliferative Action of Vitamin D-Related Compounds and Insulin-Like Growth Factor-Binding Protein 5 Accumulation
1997
Isolation and characterization of a human glutathione S-transferase Ha1 subunit gene
1992
Novel Promoter Polymorphism in Insulin-Like Growth Factor-Binding Protein-3: Correlation with Serum Levels and Interaction with Known Regulators1
2001
Genomic and Non-Genomic Mechanisms of Oxytocin Receptor Regulation
1998
Oxytocin receptor gene expression in the rat uterus during pregnancy and the estrous cycle and in response to gonadal steroid treatment.
1995
Antiproliferative action of tumor necrosis factor-alpha on MCF-7 breastcancer cells is associated with increased insulin-like growth factor binding protein-3 accumulation.
1998
Identification of nuclear cap specific proteins in HeLa cells
1987
Structure, characterization, and expression of the rat oxytocin receptor gene.
1995
Bidirectional RNA Helicase Activity of Eucaryotic Translation Initiation Factors 4A and 4F
1990
Gonadal steroid regulation of oxytocin and oxytocin receptor gene expression.
1995
Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F.
1990
A Lysine Substitution in the ATP-Binding Site of Eucaryotic Initiation Factor 4A Abrogates Nucleotide-Binding Activity
1989
Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer.
1997