Citation Impact
Citing Papers
Autonomic Nerve Development Contributes to Prostate Cancer Progression
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2005
Inhibition of the ω-conotoxin-sensitive calcium current by distinct G proteins
1992 StandoutNobel
Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial
2004
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2002 Standout
Four diterpene esters from Euphorbia myrsinites
1995
Cannabinoid analgesia
2002
Adverse Health Effects of Marijuana Use
2014 Standout
Diterpenoids from Euphorbia paralias
2001
Myeloid-related Protein (MRP) 8 and MRP14, Calcium-binding Proteins of the S100 Family, Are Secreted by Activated Monocytes via a Novel, Tubulin-dependent Pathway
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2009
The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids
2005
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1997 StandoutNatureNobel
Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae)
1997
Molecular Mechanism of the Inhibition of Phospholipase C β3 by Protein Kinase C
2000
Post-translational control of the MEF2A transcriptional regulatory protein
1999
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
Anti-tumor 12-deoxyphorbol esters from Euphorbia cornigera
2007
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ‘N of 1’ studies
2004
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Inhibitors of protein kinase C
1994
Pharmacological and biochemical interactions between opioids and cannabinoids
1999
Muscarinic Receptors—Characterization, coupling and function
1993
Polycyclic diterpenoids from Euphorbia characias
2000
Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB1 receptors in the least shrew
2001
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
2011 Standout
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
Diterpenoids and triterpenoids from Euphorbia guyoniana
2007
New 19-acetoxyingol diterpenes from the latex of Euphorbia poisonii (Euphorbiaceae)
1996
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
2002 Standout
Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw
2004
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Plant polyphenols: Biologically active compounds or non-selective binders to protein?
1997
Cannabinoids and Multiple Sclerosis
2007
The medicinal use of cannabis in the UK: results of a nationwide survey
2004
Macrocyclic diterpenoids from Euphorbia hyberna L. subsp. insularis and their reaction with oxyphilic reagents
2002
Pharmacokinetics and Pharmacodynamics of Cannabinoids
2003
A novel synthetic, nonpsychoactive cannabinoid acid (HU‐320) with antiinflammatory properties in murine collagen‐induced arthritis
2004
Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin
1990
An analgesia circuit activated by cannabinoids
1998 Nature
β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs
2002 StandoutNobel
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Epstein–Barr virus: 40 years on
2004 Standout
Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase
2005
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Munc13-1 Is a Presynaptic Phorbol Ester Receptor that Enhances Neurotransmitter Release
1998 StandoutNobel
Boron trifluoride etherate on silica-A modified lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells
1998
Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin
1992
History of Cannabis and Its Preparations in Saga, Science, and Sobriquet
2007
Protein kinase C: a physiological mediator of enhanced transmitter output
1998
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Non-CB1, Non-CB2 Receptors for Endocannabinoids, Plant Cannabinoids, and Synthetic Cannabimimetics: Focus on G-protein-coupled Receptors and Transient Receptor Potential Channels
2009
Cannabinoids in medicine: A review of their therapeutic potential
2006
Cannabidiol – Recent Advances
2007
Duration of desensitization and ultrastructural changes in dorsal root ganglia in rats treated with resiniferatoxin, an ultrapotent capsaicin analog
1989
Cannabinoids for the Treatment of Pain: An Update on Recent Clinical Trials
2005
Endocannabinoids and related fatty acid derivatives in pain modulation
2002
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Potency of Δ9–THC and Other Cannabinoids in Cannabis in England in 2005: Implications for Psychoactivity and Pharmacology*
2008
Cannabinoids and multiple sclerosis
2002
Oligomeric proanthocyanidins: naturally occurring O-heterocycles
2002
Cannabis Use in HIV for Pain and Other Medical Symptoms
2005
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
2000 StandoutNature
Toxic effect of two common Euphorbiales latices on the freshwater snail Lymnaea acuminata
2003
Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis.
1997
Cannabidiol: An Overview of Some Pharmacological Aspects
2002
Synthesis and Characterization of NESS 0327: A Novel Putative Antagonist of the CB1 Cannabinoid Receptor
2003
Therapeutic aspects of cannabis and cannabinoids
2001
Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
2004
Human Studies of Cannabinoids and Medicinal Cannabis
2005
Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review
2001
Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial
2003 Standout
Therapeutic Potential of Cannabinoids in CNS Disease
2003
Virally targeted therapies for EBV-associated malignancies
2003
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
The Effectiveness of Cannabinoids in the Management of Chronic Nonmalignant Neuropathic Pain: A Systematic Review
2015
The characterization of esulone C and chemotaxonomy of jatrophane diterpenes in leafy spurge
1987
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976
1993 Standout
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Diterpenes from Euphorbia peplus
1998
Cocarcinogenesis and tumor promoters of the diterpene Ester type as possible carcinogenic risk factors
1981
Diterpenes from Euphorbia segetalis
1998
Therapeutic potential of cannabinoid receptor agonists as analgesic agents
2005
Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes
1992
Paralinones A and B, novel diterpene esters from Euphorbia paralias
1997
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Irritant plants in the spurge family (Euphorbiaceae)
1986
Biosynthesis of Human Papillomavirus from a Continuous Cell Line Upon Epithelial Differentiation
1992 Science
Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview
2012
Tumour promoters induce mitotic aneuploidy in yeast
1981 Nature
The biosynthesis of tigliane and related diterpenoids; an intriguing problem
1987
Different biological targets for resiniferatoxin and phorbol 12-myristate 13-acetate.
1980
Dose-dependent Effects of Smoked Cannabis on Capsaicin-induced Pain and Hyperalgesia in Healthy Volunteers
2007
Jatrophane and lathyrane diterpenoid esters from north american leafy spurge seed
1992
Diterpenoids and Triterpenoids from Euphorbia retusa
2009
a new aromatic ester diterpene from Euphorbia poisonii
1976
Diterpenoids from Euphorbia fischeriana
1997
Cannabinoid Analgesia as a Potential New Therapeutic Option in the Treatment of Chronic Pain
2006
Ingol and Ingenol Diterpenes from the Aerial Parts of Euphorbia royleana and Their Antiangiogenic Activities
2009
Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons.
1991
Two new toxins from the latex of Euphorbia poisonii
1976
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Biological assays for irritant tumor-initiating and -promoting activities
1982
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Synthesis, Conformation, and Biological Activity of Teleocidin Mimics, Benzolactams. A Clarification of the Conformational Flexibility Problem in Structure−Activity Studies of Teleocidins
1996
Five ingol esters and a 17-hydroxyingenol ester from the latex of . Assignment of esters using 13C.N.M.R. methods.
1984
Tumor promoting diterpenes from Euphorbia leuconeura L.
1999
Diterpenes and Triterpenes from the Roots of <I>Euphorbia fischeriana</I>
2010
Retinoids as ligands and coactivators of protein kinase C alpha
2000
Plant Products as Antimicrobial Agents
1999 Standout
Quantitative determination of D- and L-amino acids by reaction with tert-butyloxycarbonyl-L-leucine N-hydroxysuccinimide ester and chromatographic separation as L,D and L,L dipeptides
1978 StandoutNobel
Ultraviolet derivatization of digitalis glycosides as 4-nitrobenzoates for liquid chromatographic trace analysis
1976
Cannabinoids in health and disease
2007
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Characterization of the Interaction of Ingenol 3-Angelate with Protein Kinase C
2004
Antigen Receptor-Induced Signal Transduction Imbalances Associated with the Negative Selection of Immature B Cells
1999
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
Chemical and Pharmacological Research of the Plants in Genus Euphorbia
2008 Standout
Synthesis and Evaluation of Phorboid 20-Homovanillates: Discovery of a Class of Ligands Binding to the Vanilloid (Capsaicin) Receptor with Different Degrees of Cooperativity
1996
Jatrophane derivatives and a rearranged jatrophane from Euphorbia terracina
1998
Natural product and natural product derived drugs in clinical trials
2014 Standout
Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy
2009
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Jatrophane diterpenoids from Euphorbia peplus
1999
Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
2004
Cannabinoids for Medical Use
2015 Standout
Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application
2018 Standout
Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase
2005
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Tumour promoters of the irritant diterpene ester type as risk factors of cancer in man
1987
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1
2000 StandoutNobel
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
1999
Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action
2008
Properties of a Resiniferatoxin-stimulated, Calcium Inhibited but Phosphatidylserine-dependent Kinase, which is Distinct from Protein Kinase C Isotypes α, β1γ, δ, ε and η
1995
Different Effects on Fast Exocytosis Induced by Synaptotagmin 1 and 2 Isoforms and Abundance But Not by Phosphorylation
2006 StandoutNobel
13C-NMR Data of Three Important Diterpenes Isolated from Euphorbia Species
2009
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Ingenane and lathyrane diterpenes from the latex of Euphorbia canariensis
1997
Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.
1992 Standout
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
2000
Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis
1999
Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C
2001
Efficacy of two cannabis‐based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial
2003
Ingenane and lathyrane diterpenes from the latex of euphorbia acrurensis
1998
8-methoxyingol esters from the latex of Euphorbia hermentiana
1983
Works of F.J. Evans being referenced
Characterization of phorbol ester binding to protein kinase C isotypes.
1995
NADPH-oxidase activation by protein kinase C-isotypes
1991
Inhibition of protein kinase C prevents phorbol ester- but not muscarine-induced depolarizations in the rat superior cervical ganglion
1990
Analgesic and antiinflammatory activity of constituents ofCannabis sativa L.
1988
Pain relief with oral cannabinoids in familial Mediterranean fever
1997
Toxic phorbol esters from Chinese tallow stimulate protein kinase C
1987
TPA and resiniferatoxin‐mediated activation of NADPH‐oxidase
1990
Activation of the PKC‐isotypes α, β1, γ, δ, and ε by phorbol esters of different biological activities
1991
The Composition of a Mixture of Ingol Esters fromEuphorbia kamerunica
1981
Isolation of Prostratin fromEuphorbia cornigera
1985
A phorbol ester and a daphnane ester stimulate a calcium‐independent kinase activity from human mononuclear cells
1989
Polyphenolic compounds from Croton lechleri
1991
Constituents of Egyptian Euphorbiaceae. IX. Irritant and cytotoxic ingenane esters fromEuphorbia paralias L.
1980
Some Naturrally Occurring Skin Irritants
1975
A microtechnique for the identification of diterpene ester inflammatory toxins
1975
Isolation from cannabis sativa L. of cannflavin—a novel inhibitor of prostaglandin production
1985
A BIOLOGICAL SCREEN OF SELECTED SPECIES OF THE GENUSEUPHORBIAFOR SKIN IRRITANT EFFECTS
1975
Involvement of calcium in modulation of neutrophil function by phorbol esters that activate protein kinase C isotypes and related enzymes
1993
Skin irritants of Euphorbia fortissima
1975
Cannflavin A and B, prenylated flavones fromCannabis sativa L.
1986
A comparative phytochemical study of the diterpenes of some species of the genera Euphorbia and Elaeophorbia (Euphorbiaceae)
1977
A new ingenol type diterpene from the irritant fractions of Euphorbia myrsinites and Euphorbia biglandulosa
1974
Investigations into the mode of action of the cocarcinogen 12-O-tetradecanoyl-phorbol-13-acetate using auxotrophic bacteria.
1977
High-pressure liquid chromatography of digitoxigenin and its glycosides
1974
Pro-Inflammatory, Tumour-Promoting and Anti-Tumour Diterpenes of the Plant Families Euphorbiaceae and Thymelaeaceae
1983
Biologically active diterpene esters from euphorbia peplus
1985
The effect of daphnane esters on platelet aggregation and erythema of the mouse ear
1980
Activation of phospholipase A2 by cannabinoids
1987
The medicinal uses of cannabis and its constituents
1989
The Inhibitory Effects of Cannabinoids, The Active Constituents of Cannabis sativa L. on Human and Rabbit Platelet Aggregation
1989
Induction of Epstein-Barr virus lytic cycle by tumor-promoting and non-tumor-promoting phorbol esters requires active protein kinase C
1991
New diesters of 12-deoxy-phorbol
1975
Candletoxins A and B, 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, from the irritant latex of Euphorbia poisonii Pax
1977
Sapintoxin A, a new biologically active nitrogen containing phorbol ester
1981
Thin-layer chromatographic behaviour of the acetates of some polyfunctional diterpene alcohols of toxicological interest
1973
Macrocyclic diterpene esters from Euphorbia royleana
1984