Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2
2003 StandoutScience
Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
2002 StandoutScience
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
2010 StandoutScience
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1
2004 Standout
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
2011 Nature
Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?
2010
The General Transcription Machinery and General Cofactors
2006
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Histone trimethylation and the maintenance of transcriptional ONand OFF states by trxG and PcG proteins
2006
ESC, ESCL and their roles in Polycomb Group mechanisms
2008
Methylation of H3K4 Is Required for Inheritance of Active Transcriptional States
2010
Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites
2002
Imprinted X inactivation maintained by a mouse Polycomb group gene
2001
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
2010 Nature
Epigenetic regulation of aging stem cells
2011
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns
2009
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Polycomb group protein complexes: do different complexes regulate distinct target genes?
1999
Histone methylation: a dynamic mark in health, disease and inheritance
2012 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Mechanisms of transcriptional memory
2001
A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human Retinoblastoma Binding Protein 2
2000
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms
2008
Histone methylation makes its mark on longevity
2011
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
2006 Standout
The Epigenomics of Cancer
2007 Standout
Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas
2010
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Genomic imprinting and seed development: endosperm formation with and without sex
2001
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
2002
Role of the polycomb protein EED in the propagation of repressive histone marks
2009 Nature
Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells
2010
Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans
2011
ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases
2014
Chromatin silencing and activation by Polycomb and trithorax group proteins
2001
Polycomb Group proteins: an evolutionary perspective
2007
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities
2006
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
The polycomb group protein EZH2 is involved in progression of prostate cancer
2002 StandoutNature
Polycomb-like 2 Associates with PRC2 and Regulates Transcriptional Networks during Mouse Embryonic Stem Cell Self-Renewal and Differentiation
2010
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression
2004 StandoutNobel
The Role of Chromatin during Transcription
2007 Standout
Establishment of Polycomb silencing requires a transient interaction between PC and ESC
2001
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27
2004
Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes
2002
Stabilization of Chromatin Structure by PRC1, a Polycomb Complex
1999
Modification of Enhancer Chromatin: What, How, and Why?
2013
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Modulation of EZH2 expression in T cells improves efficacy of anti–CTLA-4 therapy
2018 StandoutNobel
Polycomb complexes repress developmental regulators in murine embryonic stem cells
2006 StandoutNature
Polycomb complexes and silencing mechanisms
2004
The Polycomb group protein EZH2 directly controls DNA methylation
2005 StandoutNature
The H3K27 demethylase UTX‐1 regulates C. elegans lifespan in a germline‐independent, insulin‐dependent manner
2011
A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers
2004
Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes
2007
Polycomb Complexes and the Propagation of the Methylation Mark at the Drosophila Ubx Gene
2006
The role of senescent cells in ageing
2014 StandoutNature
Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
2007 Standout
The Hallmarks of Aging
2013 Standout
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
The many faces of histone lysine methylation
2002
MLL Targets SET Domain Methyltransferase Activity to Hox Gene Promoters
2002
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma
2001
EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency
2008
MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
2014
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes
2003
A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
2017
Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex
2002
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
CHD7 cooperates with PBAF to control multipotent neural crest formation
2010 StandoutNature
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
Division of labor in Polycomb group repression
2004
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
2003
Lysosome-mediated processing of chromatin in senescence
2013
Su(z)12, a novelDrosophilaPolycomb group gene that is conserved in vertebrates and plants
2001
Chromatin and oxygen sensing in the context of JmjC histone demethylases
2014
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Epigenetic Reprogramming in Mammalian Development
2001 StandoutScience
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Reactivation of the Paternal X Chromosome in Early Mouse Embryos
2004 StandoutScienceNobel
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Ezh2 Requires PHF1 To Efficiently Catalyze H3 Lysine 27 Trimethylation In Vivo
2008
Recruitment ofDrosophilaPolycomb-group proteins by Polycomblike, a component of a novel protein complex in larvae
2008
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Polycomb recruitment to DNA in vivo by the YY1 REPO domain
2006
Multiple levels of transcriptional and post-transcriptional regulation are required to define the domain of Hoxb4 expression
2003
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Epigenetic Regulation of Cellular Memory by the Polycomb and Trithorax Group Proteins
2004
Histone H3K27ac separates active from poised enhancers and predicts developmental state
2010 Standout
PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator
2005 StandoutScienceNobel
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
2006 StandoutNobel
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis
2010
Mechanisms of Polycomb gene silencing: knowns and unknowns
2009
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression
2011
Works of Feng Tie being referenced
Drosophila ESC-like can substitute for ESC and becomes required for Polycomb silencing if ESC is absent
2007
Polycomb group proteins ESC and E(Z) are present in multiple distinct complexes that undergo dynamic changes during development
2003
The N Terminus of Drosophila ESC Binds Directly to Histone H3 and Is Required for E(Z)-Dependent Trimethylation of H3 Lysine 27
2007
A 1-Megadalton ESC/E(Z) Complex from Drosophila That Contains Polycomblike and RPD3
2003
The Drosophila Polycomb Group proteins ESC and E(Z) bind directly to each other and co-localize at multiple chromosomal sites
1998
The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3
2001
CBP-mediated acetylation of histone H3 lysine 27 antagonizesDrosophilaPolycomb silencing
2009
Mouse homolog of theDrosophila Pc-G geneesc exerts a dominant negative effect inDrosophila
2000
Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance
2009
Histone Demethylase UTX and Chromatin Remodeler BRM Bind Directly to CBP and Modulate Acetylation of Histone H3 Lysine 27
2012