Citation Impact
Citing Papers
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Serum Amyloid A Activates the NLRP3 Inflammasome and Promotes Th17 Allergic Asthma in Mice
2011
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
The NEDD8 Pathway Is Essential for SCFβ-TrCP-mediated Ubiquitination and Processing of the NF-κB Precursor p105
2002 StandoutNobel
Cancer chemoprevention with dietary phytochemicals
2003 Standout
Photodynamic Therapy
1998 Standout
Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly
2013
Auxiliary‐Mediated Site‐Specific Peptide Ubiquitylation
2007
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
The IKK complex: an integrator of all signals that activate NF-κB?
2000
Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells
1999
NF-κB in cancer: from innocent bystander to major culprit
2002 Standout
Metabolic syndrome meets osteoarthritis
2012
Cysteine Promoted C‐Terminal Hydrazinolysis of Native Peptides and Proteins
2013 StandoutNobel
Shared Principles in NF-κB Signaling
2008 Standout
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Tumor Necrosis Factor α-induced Phosphorylation of RelA/p65 on Ser529 Is Controlled by Casein Kinase II
2000
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
2020
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Role of Drosophila IKKγ in a Toll-independent antibacterial immune response
2000 StandoutNobel
Osteoarthritis
2015 Standout
CD22 is a negative regulator of B-cell receptor signalling
1997 Nobel
Missing Pieces in the NF-κB Puzzle
2002 Standout
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Monovalent, reduced-size quantum dots for imaging receptors on living cells
2008 StandoutNobel
Toll-like receptor signalling
2004 Standout
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase
2000
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Metabolic biotinylation of recombinant antibody by biotin ligase retained in the endoplasmic reticulum
2007
Instrumental biosensors: new perspectives for the analysis of biomolecular interactions
1999
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases
1999
Characterization of the Recombinant IKK1/IKK2 Heterodimer
2000
Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase
2000 StandoutNobel
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2
2002
NF-κB regulation in the immune system
2002 Standout
The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions
1998
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Signaling to NF-κB
2004 Standout
Rapid Tyrosine Phosphorylation of HS1 in the Response of Mouse Lymphoma L5178Y‐R Cells to Photodynamic Treatment Sensitized by the Phthalocyanine Pc 4
1997
Mechanism of processing of the NF-κB2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCFβ-TrCP ubiquitin ligase
2003 StandoutNobel
NF-κB: a key role in inflammatory diseases
2001 Standout
The NF-κB Activation Pathway:A Paradigm in Information Transfer from Membrane to Nucleus
1999
Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain
2000 Standout
Immunofluorescence assay and flow-cytometry selection of bead-bound aptamers
2003
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
NF-κB: linking inflammation and immunity to cancer development and progression
2005 Standout
Serum Amyloid A Is an Endogenous Ligand That Differentially Induces IL-12 and IL-23
2006
Auxiliary‐Mediated Site‐Specific Peptide Ubiquitylation
2007
Functional Nucleic Acid Sensors
2009 Standout
Crystal Structures of Protein-Bound Cyclic Peptides
2019
Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses
2008 StandoutNobel
Adipokines and Osteoarthritis: Novel Molecules Involved in the Pathogenesis and Progression of Disease
2011
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
CD22, A B LYMPHOCYTE–SPECIFIC ADHESION MOLECULE THAT REGULATES ANTIGEN RECEPTOR SIGNALING*
1997
Crucial Role of the Amino-Terminal Tyrosine Residue 42 and the Carboxyl-Terminal PEST Domain of IκBα in NF-κB Activation by an Oxidative Stress
2000
NF‐κB activation through IKK‐i‐dependent I‐TRAF/TANK phosphorylation
2000
Mechanisms Underlying Ubiquitination
2001 Standout
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Knee osteoarthritis has doubled in prevalence since the mid-20th century
2017 Standout
Continuous inertial focusing, ordering, and separation of particles in microchannels
2007 Standout
Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation
2013 Standout
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCFβ-TrCP-Dependent Degradation and SCFβ-TrCP-Independent Processing
2003 StandoutNobel
The Ubiquitin Code
2012 Standout
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 Standout
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
2001 Standout
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Targeting Deubiquitinases Enabled by Chemical Synthesis of Proteins
2012
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain.
1992
Works of Felix Freuler being referenced
Structural Determinants of MALT1 Protease Activity
2012
Reversible translocation of p115‐RhoGEF by G12/13‐coupled receptors
2008
All three IκB isoforms and most Rel family members are stably associated with the IκB kinase 1/2 complex
1999
Evaluation of two novel tag-based labelling technologies for site-specific modification of proteins
2006
Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2
2005
Tyrosine-phosphorylated forms of Ig β CD22, TCR ζ and HOSS are major ligands for tandem SH2 domains of Syk
1995
In vitro characterization of major ligands for Src homology 2 domains derived from protein tyrosine kinases, from the adaptor protein SHC and from GTPase‐activating protein in Ramos B cells
1994
Rapid Identification of Phosphopeptide Ligands for SH2 Domains
1996
The Kinetics of Association and Phosphorylation of IκB Isoforms by IκB Kinase 2 Correlate with Their Cellular Regulation in Human Endothelial Cells
1999
Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action
2015
Serum Amyloid A (apoSAA) Expression Is Up-Regulated in Rheumatoid Arthritis and Induces Transcription of Matrix Metalloproteinases
2001