Citation Impact
Citing Papers
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract
2004 Standout
gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission
2007 StandoutNobel
Novel therapeutic strategies targeting HIV integrase
2012
Inhibiting sexual transmission of HIV-1 infection
2003
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Chemokine Receptors of T Cells and of B Cells in Lymphatic Filarial Infection: A Role for CCR9 in Pathogenesis
2005
Rethinking amide bond synthesis
2011 StandoutNature
Open Babel: An open chemical toolbox
2011 Standout
The Relative Activity of “Function Sparing” HIV-1 Entry Inhibitors on Viral Entry and CCR5 Internalization: Is Allosteric Functional Selectivity a Valuable Therapeutic Property?
2008
Spirodiketopiperazine-based CCR5 antagonists: Lead optimization from biologically active metabolite
2006
Newly approved integrase inhibitors for clinical treatment of AIDS
2014
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
2015 StandoutNobel
The role of sexually transmitted diseases in HIV transmission
2004 Standout
How were new medicines discovered?
2011 Standout
The CCR5 Receptor-Based Mechanism of Action of 873140, a Potent Allosteric Noncompetitive HIV Entry Inhibitor
2005
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Modulators of the human CCR5 receptor. Part 3: SAR of substituted 1-[3-(4-methanesulfonylphenyl)-3-phenylpropyl]-piperidinyl phenylacetamides
2006
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Comprehensive analysis of kinase inhibitor selectivity
2011 Standout
wwLigCSRre: a 3D ligand-based server for hit identification and optimization
2009
Enhancements of screening collections to address areas of unmet medical need: an industry perspective
2010
Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles
2006
Impact of high-throughput screening in biomedical research
2011 Standout
Rings in Drugs
2014 Standout
Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening
2010
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations
2018
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Rationalizing Tight Ligand Binding through Cooperative Interaction Networks
2011
Use of a Small Molecule CCR5 Inhibitor in Macaques to Treat Simian Immunodeficiency Virus Infection or Prevent Simian–Human Immunodeficiency Virus Infection
2003
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 2. Bi- and Tricyclic Derivatives Result in Superior Antiviral and Pharmacokinetic Profiles
2013
Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies
2019 StandoutNobel
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
2015 Standout
A Facile Access to Primary Alkylamines and Anilines via Ir(III)-Catalyzed C–H Amidation Using Azidoformates
2016
Assessing Atropisomer Axial Chirality in Drug Discovery and Development
2011 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
2015 update of the drug resistance mutations in HIV-1
2015
Macrophage plasticity and polarization in tissue repair and remodelling
2012 Standout
Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology
2012 Standout
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
2012 Standout
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Works of Felix Deanda being referenced
Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R: Elimination of an acid-mediated decomposition pathway
2008
Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics
2013
Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase
2009
Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitors
2003
Discovery of Bioavailable 4,4-Disubstituted Piperidines as Potent Ligands of the Chemokine Receptor 5 and Inhibitors of the Human Immunodeficiency Virus-1
2008
Kinase-Targeted Library Design through the Application of the PharmPrint Methodology
2008
Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes
2011