Citation Impact
Citing Papers
Targeting and tracing of specific DNA sequences with dTALEs in living cells
2013
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
2011 StandoutScience
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Rationally engineered Cas9 nucleases with improved specificity
2015 StandoutScience
RNA-seq pinpoints a Xanthomonas TAL-effector activated resistance gene in a large-crop genome
2012
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells
2007 Science
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Overcoming Transcription Activator-like Effector (TALE) DNA Binding Domain Sensitivity to Cytosine Methylation
2012
Synergistic and tunable human gene activation by combinations of synthetic transcription factors
2013
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Epigenetic mechanisms in mammals
2008
Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification
2018
Structure and Hemimethylated CpG Binding of the SRA Domain from Human UHRF1
2008
Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma
2012
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
2010 Standout
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
RNA-guided gene activation by CRISPR-Cas9–based transcription factors
2013
Transcription activator‐like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing
2013
A guide to genome engineering with programmable nucleases
2014 Standout
Tet1 and 5-hydroxymethylation
2011
DNA targeting specificity of RNA-guided Cas9 nucleases
2013 Standout
Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain
2011
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
2013
MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System
2012
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
The Discovery of 5‐Formylcytosine in Embryonic Stem Cell DNA
2011
Comprehensive analysis of the specificity of transcription activator-like effector nucleases
2014
Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells
1999
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
2011
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
2015
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
2007 Nature
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates
2010
Identification and functional analysis of 9p24 amplified genes in human breast cancer
2011
TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation
2011
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
2008 StandoutNature
Robust, synergistic regulation of human gene expression using TALE activators
2013
H3K9 methyltransferase G9a and the related molecule GLP
2011
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
2011 Nature
The complex language of chromatin regulation during transcription
2007 StandoutNature
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
Hydroxylation mediates chromatin demethylation
2012
Genomic mapping of 5-hydroxymethylcytosine in the human brain
2011
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase
2011
DNA Methylation and Its Basic Function
2012 Standout
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Tunicates and not cephalochordates are the closest living relatives of vertebrates
2006 StandoutNature
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
De novo design of bioactive protein switches
2019 StandoutNatureNobel
A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples
2011
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
2011 Nature
Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica
2004 Nature
Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells
2011
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
2010
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes
2010
Points of control in inflammation
2002 StandoutNature
Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
2009 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
2001 StandoutNature
NEW EMBO MEMBERS' REVIEW: The double life of HMGB1 chromatin protein: architectural factor and extracellular signal
2001
A library of TAL effector nucleases spanning the human genome
2013
Identification of direct targets and modified bases of RNA cytosine methyltransferases
2013
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
2011 Nature
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Flexing DNA: HMG-Box Proteins and Their Partners
1998
Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells
2011
Relationship between Gene Body DNA Methylation and Intragenic H3K9me3 and H3K36me3 Chromatin Marks
2011
Chromatin structure and the inheritance of epigenetic information
2010
Mapping recently identified nucleotide variants in the genome and transcriptome
2012
Synthetic protein–protein interaction domains created by shuffling Cys 2 His 2 zinc‐fingers
2006
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
1999 StandoutScience
Pivoting the Plant Immune System from Dissection to Deployment
2013 StandoutScience
Mammalian Neural Stem Cells
2000 StandoutScience
Regulation of DNA-Dependent Activities by the Functional Motifs of the High-Mobility-Group Chromosomal Proteins
1999
Late changes in spliceosomal introns define clades in vertebrate evolution
1999 StandoutNobel
Neural stem cells: From fly to vertebrates
1998
The Curious Chemical Biology of Cytosine: Deamination, Methylation,and Oxidation as Modulators of Genomic Potential
2011
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells
2001
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
2010
Imaging Specific Genomic DNA in Living Cells
2016
MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system
2013
TALENs: a widely applicable technology for targeted genome editing
2012
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN
2005
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
De novo insertion of an intron into the mammalian sex determining gene, SRY
1998
CD1: Antigen Presentation and T Cell Function
2004
Syntheses of 5-Formyl- and 5-Carboxyl-dC Containing DNA Oligos as Potential Oxidation Products of 5-Hydroxymethylcytosine in DNA
2011
The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice
1999
Works of Fabio Spada being referenced
Interaction of normal and mutant SRY proteins with DNA
1995
CD1d structure and regulation on human thymocytes, peripheral blood T cells,B cells and monocytes
2000
Emx and Otx Gene Expression in the Developing Mouse Brain
2007
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA
2010
The multi-domain protein Np95 connects DNA methylation and histone modification
2009
Trapped in action: direct visualization of DNA methyltransferase activity in living cells
2005
Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5–hydroxymethylcytosine
2011
Molecular Patterning of the Oikoplastic Epithelium of the Larvacean Tunicate Oikopleura dioica
2001
Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1
2011
High mobility group 1 (HMG1) protein in mouse preimplantation embryos
1998
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
2007
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
2009
Histone mRNAs Do Not Accumulate during S Phase of either Mitotic or Endoreduplicative Cycles in the Chordate Oikopleura dioica
2004
High Mobility Group 1 Protein Is Not Stably Associated with the Chromosomes of Somatic Cells
1997
The PHD Domain of Np95 (mUHRF1) Is Involved in Large-Scale Reorganization of Pericentromeric Heterochromatin
2008
Ikaros Family Members from the Agnathan Myxine glutinosa and the Urochordate Oikopleura dioica: Emergence of an Essential Transcription Factor for Adaptive Immunity
2003
Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers
2012
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
2007