Fabio Giannessi

Sirtuins as regulators of metabolism and healthspan

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

Dissociating fatty liver and diabetes

The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment

Carnitine palmitoyltransferase 2: Analysis of membrane association and complex structure with a substrate analog

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Structures of membrane proteins

Discovery and development of selective PPARγ modulators as safe and effective antidiabetic agents

The ChEMBL database in 2017

The chemistry and biology of organic guanidine derivatives

Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design

Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport

Type 2 diabetes mellitus

Regulatory enzymes of mitochondrial β‐oxidation as targets for treatment of the metabolic syndrome

A brain-liver circuit regulates glucose homeostasis

A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO₂+” Donor of Unprecedented Reactivity, Selectivity, and Scope

Preparation of Unsymmetrical Sulfonylureas from N,N‘-Sulfuryldiimidazoles

Mechanisms of Insulin Action and Insulin Resistance

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research

Merobatzelladines A and B, Anti-Infective Tricyclic Guanidines from a Marine Sponge Monanchora sp.

Advances in the Chemistry of Tetrahydroquinolines

Obesity-Related Derangements in Metabolic Regulation

Visualizing tmRNA Entry into a Stalled Ribosome

Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care

Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1α: implications for metabolic disease

Annona muricata: A comprehensive review on its traditional medicinal uses, phytochemicals, pharmacological activities, mechanisms of action and toxicity

Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In Vivo

A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO₂+” Donor of Unprecedented Reactivity, Selectivity, and Scope

Efecto hipoglicemiante coadyuvante del extracto etanólico de hojas de Annona muricata L (guanábana), en pacientes con diabetes tipo 2 bajo tratamiento de glibenclamida

Aminocarnitine Ureidic Derivatives as Inhibitors of Carnitine Palmitoyltransferase I

Effects of the increase in neuronal fatty acids availability on food intake and satiety in mice

In Vivo Imaging Reveals Selective Peroxisome Proliferator Activated Receptor Modulator Activity of the Synthetic Ligand 3-(1-(4-Chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886)

Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis

Reversible Carnitine Palmitoyltransferase Inhibitors with Broad Chemical Diversity as Potential Antidiabetic Agents

Isolation and Pharmacological Activities of the Tecoma Stans Alkaloids.

Discovery of a Long-Chain Carbamoyl Aminocarnitine Derivative, a Reversible Carnitine Palmitoyltransferase Inhibitor with Antiketotic and Antidiabetic Activity

Novel Substituted Aminoalkylguanidines as Potential Antihyperglycemic and Food Intake-Reducing Agents