Citation Impact

Citing Papers

Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
2010
JAM-A regulates permeability and inflammation in the intestine in vivo
2007
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
Interleukin 37 expression protects mice from colitis
2011
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
2007 Standout
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
2012
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease.
1993
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
2009
Mechanism of IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability
2008
Phenotype and Effector Function of CC Chemokine Receptor 9-Expressing Lymphocytes in Small Intestinal Crohn’s Disease
2007
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Why not treat human cancer with interleukin-1 blockade?
2010
A core gut microbiome in obese and lean twins
2008 StandoutNature
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.
1995
Cytokines in inflammatory bowel disease
2014 Standout
Experimental models of inflammatory bowel disease
1995 Standout
Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21
2006
Crohn's disease
2002
Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases
2010
TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation
2008
Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease
2012
Temporal and Spatial Analysis of Clinical and Molecular Parameters in Dextran Sodium Sulfate Induced Colitis
2009
Animal models of mucosal inflammation and their relation to human inflammatory bowel disease
1999
Th1/Th17 Immune Response Is Induced by Mesenteric Lymph Node Dendritic Cells in Crohn's Disease
2009
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
2005
Impaired response of activated mononuclear phagocytes to interleukin 4 in inflammatory bowel disease
1995
Probiotics (Lactobacillus acidophilus and Bifidobacterium bifidum) prevent NEC in VLBW infants fed breast milk but not formula
2014
Lymphocyte-Dependent and Th2 Cytokine-Associated Colitis in Mice Deficient in Wiskott-Aldrich Syndrome Protein
2007
Future trends in the development of safer nonsteroidal anti-inflammatory drugs
1998
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Mechanism of Action of Anti-Inflammatory Drugs
1996
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells
2006
Regulatory T Cells
2000 StandoutNobel
Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-γ, in mucosal inflammation
2004
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.
1996
Cell-Cell Contacts Prevent Anoikis in Primary Human Colonic Epithelial Cells
2006
Nonsteroidal anti-inflammatory drug-induced gastrointestinal injury
1996
Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis
2008
Layers of mutualism with commensal bacteria protect us from intestinal inflammation
2006
Randomised trial of eradication of Helicobacter pylori before non-steroidal anti-inflammatory drug therapy to prevent peptic ulcers
1997
Purinergic regulation of the immune system
2016
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
2005
Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis
1995
Inflammatory Bowel Disease
2009 Standout
Relationship of functional and antigenic interleukin 6 to disease activity in inflammatory bowel disease
1993
Randomized, controlled trial of recombinant human interleukin‐11 in patients with active Crohn's disease
2002
TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway
2000
Cytokines in intestinal inflammation: Pathophysiological and clinical considerations
1994
Regulation of Chemokine Expression by Antiinflammatory Cytokines
2002
Metagenomic biomarker discovery and explanation
2011 Standout
LIGHT Signals Directly to Intestinal Epithelia to Cause Barrier Dysfunction via Cytoskeletal and Endocytic Mechanisms
2007
Role of the gut microbiota in immunity and inflammatory disease
2013 Standout
RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection
2010
T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn’s disease
2004
Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis
1999
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Microbial Influences in Inflammatory Bowel Diseases
2008
Inflammatory Bowel Disease
1991 Standout
Intestinal Epithelial Stem Cells and Progenitors
2006
The role of Th1/Th2 polarization in mucosal immunity
2002
Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease
1995
Infliximab Maintenance Therapy for Fistulizing Crohn's Disease
2004 Standout
Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(−/−) mice
2008
The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation
2010
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
2006
AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2
2007
Intestinal mucosal barrier function in health and disease
2009 Standout
Interleukin-6 trans-signaling in inflammatory bowel disease
2006
Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo
2006
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
IL‐1, IL‐18, and IL‐33 families of cytokines
2008
Diet rapidly and reproducibly alters the human gut microbiome
2013 StandoutNature
The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants
2017 Standout
Adalimumab induces apoptosis of human monocytes: a comparative study with infliximab and etanercept
2005
The relation between Helicobacter pylori and nonsteroidal anti-inflammatory drugs
1998
Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist
1994
Compartmentalized Expression of Th1 and Th17 Cytokines in Pediatric Inflammatory Bowel Diseases
2011
Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis
2006
Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs
1999 Standout
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
2011 Nature
Tumor necrosis factor signaling
2003 Standout
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
2008 Standout
Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics
2004
Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
2008
Origin and physiological roles of inflammation
2008 StandoutNature
IFN-γ-Induced TNFR2 Expression Is Required for TNF-Dependent Intestinal Epithelial Barrier Dysfunction
2006
Anti-inflammatory drugs and their mechanism of action
1998 Nobel
Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease
1996
Eicosanoids and the gastrointestinal tract
1995
Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis
2008
Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats
1996
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2−/− mice
2009 StandoutNobel
Interleukin-15-Dependent NKp46+ Innate Lymphoid Cells Control Intestinal Inflammation by Recruiting Inflammatory Monocytes
2012
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Molecular pathogenesis of inflammatory bowel disease: Genotypes, phenotypes and personalized medicine
2007
The Genetics of Inflammatory Bowel Disease
2007
Tumor necrosis factor antagonist therapy and lymphoma development: Twenty‐six cases reported to the Food and Drug Administration
2002
Getting to the site of inflammation: the leukocyte adhesion cascade updated
2007 Standout
Inflammatory bowel disease: Etiology and pathogenesis
1998 Standout
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
2002 Standout
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease
1994
The TNF and TNF Receptor Superfamilies
2001 Standout
Cancer-related inflammation
2008 StandoutNature
Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa
1995
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Interleukin-18 Promotes Joint Inflammation and Induces Interleukin-1-Driven Cartilage Destruction
2004
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
2008
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
2011
Interleukin 1 receptor antagonist. A new member of the interleukin 1 family.
1991
β‐glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice
2012
NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
2014
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Macrophage-derived IL-18–mediated intestinal inflammation in the murine model of Crohn's disease
2001
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
2000 StandoutNature
Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice
1997
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3–derived O-glycans
2007
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Clinical Aspects and Pathophysiology of Inflammatory Bowel Disease
2002
CD4+CD25LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Role of Cytokines in the Pathogenesis of Inflammatory Bowel Disease
2000
Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a−/− mice
2005
Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease
1993
Spontaneous and Continuous Cyclooxygenase-2-Dependent Prostaglandin E2 Production by Stromal Cells in the Murine Small Intestine Lamina Propria: Directing the Tone of the Intestinal Immune Response
2001
The T Cell Costimulator TL1A Is Induced by FcγR Signaling in Human Monocytes and Dendritic Cells
2007
TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease
2009
The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
2008
The Immunology of Mucosal Models of Inflammation
2002
A CRISPR screen defines a signal peptide processing pathway required by flaviviruses
2016 Nature
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
HIF‐dependent induction of adenosine A2B receptor in hypoxia
2006
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Circulating antiinflammatory cytokine IL-10 in patients with inflammatory bowel disease (IBD)
1995
Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis
2010
Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production
2001
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Oxazolone Colitis: A Murine Model of  T Helper Cell Type 2 Colitis Treatable with Antibodies to Interleukin 4
1998
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
The Intestinal Microvasculature as a Therapeutic Target in Inflammatory Bowel Disease
2006
Myofibroblasts. II. Intestinal subepithelial myofibroblasts
1999
The precursor form of IL-1α is an intracrine proinflammatory activator of transcription
2004
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Anti-TNF Therapy and Malignancy – A Critical Review
2001
Development and Application of a Reverse Genetics System for Japanese Encephalitis Virus
2003 StandoutNobel
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
2002
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
The Role of FcγR Signaling in the K/B × N Serum Transfer Model of Arthritis
2002
Hapten-induced model of murine inflammatory bowel disease: mucosa immune responses and protection by tolerance.
1996
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis
2018 StandoutNobel
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
Biologic therapy for inflammatory bowel disease
1997
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel

Works of Fabio Cominelli being referenced

Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis
2006
Probiotics promote gut health through stimulation of epithelial innate immunity
2009
IL-18, a Novel Immunoregulatory Cytokine, Is Up-Regulated in Crohn’s Disease: Expression and Localization in Intestinal Mucosal Cells
1999
Commensal Bacteria Exacerbate Intestinal Inflammation but Are Not Essential for the Development of Murine Ileitis
2007
In Vivo Inhibition of RIPK2 Kinase Alleviates Inflammatory Disease
2014
Proinflammatory cytokines differentially modulate their own expression in human intestinal mucosal mesenchymal cells
1998
MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages
2007
Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis
1992
The relationship between infliximab treatment and lymphoma in Crohn's disease
1999
Genetic deletion of the bacterial sensor NOD2 improves murine Crohn's disease-like ileitis independent of functional dysbiosis
2016
Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation
2005
Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis
2006
Linkage to peroxisome proliferator-activated receptor-γ in SAMP1/YitFc mice and in human Crohn’s disease
2005
Targeting Mucosal Addressin Cellular Adhesion Molecule (MAdCAM)-1 to Noninvasively Image Experimental Crohn’s Disease
2006
Immunopathogenesis of inflammatory bowel disease: current concepts
2007
Mouse models for the study of Crohn's disease
2003
A ‘minimal’ approach in design of flavivirus infectious DNA
2001
Regulation of eicosanoid production in rabbit colon by interleukin-1
1989
Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis.
1994
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements
1999
Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice
2001
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis
2003
Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis.
1990
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn’s disease
2001
A randomized, double-blind comparison of placebo, etodolac, and naproxen on gastrointestinal injury and prostaglandin production
1995
Altered Epithelial Cell Lineage Allocation and Global Expansion of the Crypt Epithelial Stem Cell Population Are Associated with Ileitis in SAMP1/YitFc Mice
2005
Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitis
1999
Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn’s disease: SAMP1/YitFc
2003
Activation of A2A Adenosine Receptor Attenuates Intestinal Inflammation in Animal Models of Inflammatory Bowel Disease
2005
Effects of 16,16-dimethyl prostaglandin E2 and indomethacin on leukotriene B4 and inflammation in rabbit colitis
1988
Interaction of NSAIDs and Helicobacter pylori on gastrointestinal injury and prostaglandin production: a controlled double‐blind trial
1995
Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins.
1990
Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells
1993
Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease
1989
Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease
2004
Cytokine Therapy for Crohn's Disease: Advances in Translational Research
2007
Characterization of a new spontaneous murine model of inflammatory bowel disease
1998
Genetic Dissection of the Cellular Pathways and Signaling Mechanisms in Modeled Tumor Necrosis Factor–induced Crohn's-like Inflammatory Bowel Disease
2002
Down-Regulation of Intestinal Lymphocyte Activation and Th1 Cytokine Production by Antibiotic Therapy in a Murine Model of Crohn’s Disease
2002
Expression, Localization, and Functional Activity of TL1A, a Novel Th1-Polarizing Cytokine in Inflammatory Bowel Disease
2003
XI. Novel mouse models to study pathogenic mechanisms of Crohn's disease
2000
Role of TL1A and its receptor DR3 in two models of chronic murine ileitis
2006
A randomized, double-blind, placebo-controlled, multi-center trial of the engineered human anti body to TNF (CDP571) for steroid sparing and maintenance of remission in patients with steroid-dependent Crohn's disease
2000
Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation.
1994
The primary defect in experimental ileitis originates from a nonhematopoietic source
2006
RIP2 activity in inflammatory disease and implications for novel therapeutics
2013
L-Selectin, α4β1, and α4β7 Integrins Participate in CD4+ T Cell Recruitment to Chronically Inflamed Small Intestine
2005
Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease
2004
Inflammatory mediators of inflammatory bowel disease
1993
New Concepts in the Pathophysiology of Inflammatory Bowel Disease
2005
Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation.
1995
Genetic analysis of susceptibility to ileitis in a spontaneous mouse model of Crohn's disease
2001
TNF-αneutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis
2003
Interleukin‐1 and interleukin‐1 receptor antagonist in inflammatory bowel disease.
1996
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