Citation Impact
Citing Papers
Serum Albumin
1985 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
1994 StandoutNature
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
I. Specificity of the glutathione S-transferases in the conversion of leukotriene A4 to leukotriene C4
1987 StandoutNobel
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Tumors are unique organs defined by abnormal signaling and context
2001
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
2013 StandoutNature
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Ibuprofen-like activity in extra-virgin olive oil
2005 StandoutNature
Physiology of Cell Volume Regulation in Vertebrates
2009
Cloning and Characterization of a Bifunctional Leukotriene A4 Hydrolase from Saccharomyces cerevisiae
1999
Inositol phosphates and cell signalling
1989 StandoutNature
Marine natural products
1990 Standout
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Prostaglandin-Induced Activation of Nociceptive Neurons via Direct Interaction with Transient Receptor Potential A1 (TRPA1)
2007
Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets
2001
Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate
1999
The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4
2015
Redirection of prostaglandin endoperoxide metabolism at the platelet-vascular interface in man.
1989
DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer
2012
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
The impact of T‐cell immunity on ovarian cancer outcomes
2008
Glial and neuronal control of brain blood flow
2010 StandoutNature
Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay
1997
Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways
2001
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Atomic structure and chemistry of human serum albumin
1992 StandoutNature
Characterization of Endothelium- Dependent Relaxation in Guinea Pig Basilar Artery – Effect of Hypoxia and Role of Cytochrome P<sub>450</sub> Mono-Oxygenase
1998
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Genetic and pharmacological analysis of prostanoid receptor function
2001
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Selective Impairment of CD4+CD25+Foxp3+Regulatory T cells by paclitaxel is explained by Bcl-2/Bax mediated apoptosis
2010
Evidence that the phosphatidylinositol cycle is linked to cell motility
1988
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation.
2001
The N-terminal “β-Barrel” Domain of 5-Lipoxygenase Is Essential for Nuclear Membrane Translocation
2001
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Pathophysiological mechanisms of sudden death induced by platelet activating factor
1984
Organic Synthesis of Prostaglandins: Advancing Biology
1993 StandoutScienceNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
A glutathione conjugate of hepoxilin A3: formation and action in the rat central nervous system.
1990 StandoutNobel
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
The effect of eicosapentaenoic acid on leukotriene B production by human neutrophils.
1984
Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase.
1986
A Second Leukotriene B4 Receptor, Blt2
2000
Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation
1983 StandoutScienceNobel
Genetic and pharmacological analysis of prostanoid receptor function
2001
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Role of Platelet-Activating Factor-Acether in Mediating Guinea Pig Anaphylaxis
1986 Science
A glutamate residue contributes to the exopeptidase specificity in aminopeptidase A
1998
Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists
1991
Leukotrienes stimulate initiation of DNA synthesis in cultured arterial smooth muscle cells
1987
1 Arachidonate Metabolism in Blood Cells and the Vessel Wall
1986
Effect of Dietary Enrichment with Eicosapentaenoic and Docosahexaenoic Acids on in Vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function
1985 StandoutNobel
The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology.
1984
Prostaglandin endoperoxide synthase: structure and catalysis
1991
Purification of arachidonate 5-lipoxygenase from porcine leukocytes and its reactivity with hydroperoxyeicosatetraenoic acids.
1986
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Strongylophorines: Natural Product Inhibitors of Hypoxia-Inducible Factor-1 Transcriptional Pathway
2008
Simulations of the Large Kinetic Isotope Effect and the Temperature Dependence of the Hydrogen Atom Transfer in Lipoxygenase
2004 StandoutNobel
9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma.
1984
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Thromboxane generation by human peripheral blood polymorphonuclear leukocytes.
1978 StandoutNobel
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Cyclic nucleotides control a system which regulates Ca2+ sensitivity of platelet secretion
1984 Nature
Quantitative determination of D- and L-amino acids by reaction with tert-butyloxycarbonyl-L-leucine N-hydroxysuccinimide ester and chromatographic separation as L,D and L,L dipeptides
1978 StandoutNobel
Leukotriene C: a slow-reacting substance from murine mastocytoma cells.
1979 StandoutNobel
Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.
1984 StandoutNobel
A new prostaglandin, C22-PGF4α, synthesized from docosahexaenoic acid (C22:6n3) by trout gill
1981
Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2
2002 StandoutScience
Anti-inflammatory Constituents of the Red AlgaGracilaria verrucosaand Their Synthetic Analogues
2008
Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide.
1992
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis.
1983 StandoutNobel
Preferential binding of growth inhibitory prostaglandins by the target protein of a carcinogen.
1990
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
2000
Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects
1987 StandoutScienceNobel
P-450 Metabolites of Arachidonic Acid in the Control of Cardiovascular Function
2002
Enzymatic synthesis of a bicyclobutane fatty acid by a hemoprotein–lipoxygenase fusion protein from the cyanobacterium Anabaena PCC 7120
2007
Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.
1983
On the structure of slow reacting substance of anaphylaxis: Evidence of biosynthesis from arachidonic acid
1977
Marked enhancement in antithrombotic activity of isocarbacyclin following its incorporation into lipid microspheres
1987
Strong and Confined Acids Enable a Catalytic Asymmetric Nazarov Cyclization of Simple Divinyl Ketones
2019 StandoutNobel
Synthesis of Chiral Cyclopentenones
2016
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
Signal Transduction through MAP Kinase Cascades
1998 Standout
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.
1986
Asymmetric synthesis of 3-amino-2-hydroxy-4-phenylbutanoate
1999
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.
1981
α-Ketocarbonyl Peptides: A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support
2001 StandoutNobel
PGF2α, thromboxane B2 and hete levels in gerbil brain cortex after ligation of common carotid arteries and decapitation
1979
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Works of F.A. Fitzpatrick being referenced
Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon.
1981
Cyclooxygenase-2 and carcinogenesis
2000
Tyrosine Kinase Activity Modulates Catalysis and Translocation of Cellular 5-Lipoxygenase
1996
Opioid peptides are substrates for the bifunctional enzyme LTA4 hydrolase/aminopeptidase
1992
Inflammation, carcinogenesis and cancer
2001
5-Lipoxygenase Compartmentalization in Granulocytic Cells Is Modulated by an Internal Bipartite Nuclear Localizing Sequence and Nuclear Factor κB Complex Formation
1998
Cyclopentenone Prostaglandins of the J Series Inhibit the Ubiquitin Isopeptidase Activity of the Proteasome Pathway
2001
Regulated formation of eicosanoids
2001
The immunopharmacology of paclitaxel (Taxol®), docetaxel (Taxotere®), and related agents
2003
Biological activity and metabolism of 20‐hydroxyeicosatetraenoic acid in the human platelet
1992
Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks Activation and Redistribution of 5-Lipoxygenase in HL-60 Cells
1996
Cyclooxygenase-2 induction by paclitaxel, docetaxel, and taxane analogues in human monocytes and murine macrophages: structure-activity relationships and their implications.
2002
Triene prostaglandins: Prostaglandin D 3 and icosapentaenoic acid as potential antithrombotic substances
1979
Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit
1983
A selective thromboxane synthetase inhibitor blocks the cAMP lowering activity of PGH2
1977
9,11-Epoxyiminoprosta-5,13-dienoic acid is a thromboxane A2 antagonist in human platelets
1978 Nature
A radioimmunoassay for thromboxane B2
1977
Oximes for high performance liquid and electron capture gas chromatography of prostaglandins and thromboxanes
1977
Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes
1991
Punaglandins, Chlorinated Prostaglandins, Function as Potent Michael Receptors To Inhibit Ubiquitin Isopeptidase Activity
2004
Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids.
1988
Albumin stabilizes leukotriene A4.
1982
Albumins stabilize prostaglandin I2
1980
In Vivo and In Vitro Actions of a New Selective Inhibitor of Leukotriene C and D Synthesis
1983
In vivo suppression of prostaglandin biosynthesis by non-steroidal anti-inflammatory agents
1976
5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins.
1994
Hemoprotein catalysis of leukotriene formation
1984 Nobel
Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril.
1991
Albumin-lipid interactions: prostaglandin stability as a probe for characterizing binding sites on vertebrate albumins
1981
The bifunctional enzyme leukotriene-A4 hydrolase is an arginine aminopeptidase of high efficiency and specificity
1994
Mechanism-based inactivation of leukotriene A4 hydrolase/aminopeptidase by leukotriene A4. Mass spectrometric and kinetic characterization
1992
Inhibition of human platelet thromboxane synthetase by 9,11-azoprosta-5,13-dienoic acid.
1977
“Suicide” inactivation of thromboxane A2 synthase. Characteristics of mechanism-based inactivation with isolated enzyme and intact platelets
1990
Albumin-eicosanoid interactions. A model system to determine their attributes and inhibition.
1984