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Atherosclerosis — An Inflammatory Disease
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A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
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The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes
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Atherosclerosis
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1992
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AMP‐activated protein kinase: the energy charge hypothesis revisited
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Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors
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Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease
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Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects
1999
Hyperhomocysteinemia as a Risk Factor for Deep-Vein Thrombosis
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The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia
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Homocyst(e)ine, Diet, and Cardiovascular Diseases
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Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
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A Common Variant in Methionine Synthase Reductase Combined with Low Cobalamin (Vitamin B12) Increases Risk for Spina Bifida
1999
Molecular and biochemical approaches in the identification of heterozygotes for homocystinuria
1996
Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease Effects of pyridoxine and folic acid treatment
1990
Vitamin Supplementation Reduces Blood Homocysteine Levels
1998
Quantitation of total homocysteine, total cysteine, and methionine in normal serum and urine using capillary gas chromatography-mass spectrometry
1987
Hyperhomocysteinemia, Atherosclerosis and Thrombosis
1999
THE AMP-ACTIVATED/SNF1 PROTEIN KINASE SUBFAMILY: Metabolic Sensors of the Eukaryotic Cell?
1998
Redox Status and Protein Binding of Plasma Homocysteine and Other Aminothiols in Patients With Early-Onset Peripheral Vascular Disease
1995
Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease.
1989
The Mutation Ala677→Val in the Methylene Tetrahydrofolate Reductase Gene: A Risk Factor for Arterial Disease and Venous Thrombosis
1997
Higher Plasma Homocyst(e)ine and Increased Susceptibility to Adverse Effects of Low Folate in Early Familial Coronary Artery Disease
1995
Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease.
1986
Genetic Predisposition to Hyperhomocysteinemia: Deficiency of Methylenetetrahydrofolate Reductase (MTHFR)
1997
Effect of various regimens of vitamin B6 and folic acid on mild hyperhomocysteinaemia in vascular patients
1994
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1990
Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke.
1990
Luminescent Chemodosimeters for Bioimaging
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Common Methylenetetrahydrofolate Reductase Gene Mutation Leads to Hyperhomocysteinemia but Not to Vascular Disease
1998
Post-infarction left ventricular remodeling induces changes in creatine kinase mRNA and protein subunit levels in porcine myocardium.
1997
Association Between Plasma Total Homocysteine and Parental History of Cardiovascular Disease in Children With Familial Hypercholesterolemia
1997
Methylenetetrahydrofolate Reductase Polymorphism, Plasma Folate, Homocysteine, and Risk of Myocardial Infarction in US Physicians
1996
An update on the aetiology of orofacial clefts.
2004
Thermolabile Methylenetetrahydrofolate Reductase in Coronary Artery Disease
1997
Protein‐Bound Homocyst(e)ine in Patients With Rheumatoid Arthritis Undergoing D‐Penicillamine Treatment
1986
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
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Hyperhomocysteinaemia and premature coronary artery disease in the Chinese.
1996
Aggregation-Induced Emission: Together We Shine, United We Soar!
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Homocysteine and Thrombotic Disease
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The Effects of Folic Acid Supplementation on Plasma Total Homocysteine Are Modulated by Multivitamin Use and Methylenetetrahydrofolate Reductase Genotypes
1997
Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.
1996
A Common Polymorphism in the Methylenetetrahydrofolate Reductase Gene, Homocysteine, and Ischemic Cerebrovascular Disease
1997
Common Mutation in Methylenetetrahydrofolate Reductase
1996
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
2006 Standout
Review: Mitochondrial medicine--cardiomyopathy caused by defective oxidative phosphorylation.
2003
Hyperhomocysteinemia and Low Pyridoxal Phosphate
1995
Folic acid responsive postmenopausal homocysteinemia
1985
Mitochondrial Diseases in Man and Mouse
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Mitochondrial myopathies
1985
Peroxisome Biogenesis Disorders
2003
Mitochondrial creatine kinase: a major constituent of pathological inclusions seen in mitochondrial myopathies.
1994
Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.
1986
Plasma Total Homocysteine, B Vitamins, and Risk of Coronary Atherosclerosis
1997
Distribution in Healthy and Coronary Populations of the Methylenetetrahydrofolate Reductase (MTHFR) C 677 T Mutation
1996
Assessment of homocysteine status
1997
High prevalence of a mutation in the cystathionine beta-synthase gene.
1996
Correlation of a Common Mutation in the Methylenetetrahydrofolate Reductase Gene With Plasma Homocysteine in Patients With Premature Coronary Artery Disease
1997
Risk factors for venous thrombosis: prevalence, risk, and interaction.
1997
Balancing Life-Style and Genomics Research for Disease Prevention
2002 Science
Pathobiochemical implications of hyperhomocysteinemia
1994
Low Whole-Blood S -Adenosylmethionine and Correlation Between 5-Methyltetrahydrofolate and Homocysteine in Coronary Artery Disease
1996
Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease
1985
The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies
2007 Standout
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Homocysteine and Cardiovascular Disease
1998 Standout
Radial Capillary Array Electrophoresis Microplate and Scanner for High-Performance Nucleic Acid Analysis
1999
Radioenzymic determination of homocysteine in plasma and urine.
1985
Hyperhomocyst(e)inemia Is Associated With Impaired Endothelium-Dependent Vasodilation in Humans
1997
Is dietary intake of methionine associated with a reduction in risk for neural tube defect-affected pregnancies?
1997
Myocardial Infarction in Young Women in Relation to Plasma Total Homocysteine, Folate, and a Common Variant in the Methylenetetrahydrofolate Reductase Gene
1997
Venous thrombosis: a multicausal disease
1999 Standout
Disordered methionine/homocysteine metabolism in premature vascular disease. Its occurrence, cofactor therapy, and enzymology.
1993
Results of B-vitamin supplementation study used in a prediction model to define a reference range for plasma homocysteine
1995
Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.
1994
Homocysteine and Risk of Premature Coronary Heart Disease
1996
Annotation Molecular genetics of methylenetetrahydrofolate reductase deficiency
1996
Genetic Polymorphism of Methylenetetrahydrofolate Reductase and Myocardial Infarction
1996
Creatine and Creatinine Metabolism
2000 Standout
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
2002
Integrated microfluidic bioprocessor for single-cell gene expression analysis
2008 StandoutNobel
Works of F. Trijbels being referenced
Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida
1995
Maturation of Mitochondrial and other Isoenzymes of Creatine Kinase in Skeletal Muscle of Preterm Born Infants
1992
The X‐chromosomal NDUFA1 gene of complex I in mitochondrial encephalomyopathies: Tissue expression and mutation detection
1998
Mitochondrial creatine kinase containing crystals, creatine content and mitochondrial creatine kinase activity in chronic progressive external ophthalmoplegia
1992
Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient.
1996
Prevalence of familial mild hyperhomocysteinemia
1996
A Common 844INS68 Insertion Variant in the Cystathionine β-Synthase Gene
1997
A Method for Quantitative Measurement of Mitochondrial Creatine Kinase in Human Skeletal Muscle
1992
Multiple deficiencies of mitochondrial DNA- and nuclear-encoded subunits of respiratory NADH dehydrogenase detected with peptide- and subunit-specific antibodies in mitochondrial myopathies
1995 StandoutNobel
Mitochondrial creatine kinase activity in patients with disturbed energy generation in muscle mitochondria
1992
Treatment of mild hyperhomocysteinemia in vascular disease patients.
1994
A patient with lactic acidaemia and cytochrome oxidase deficiency
1983
The human NADH:ubiquinone oxidoreductase NDUFS5 (15kDa) subunit: cDNA cloning, chromosomal localization, tissue distribution and the absence of mutations in isolated complex I‐deficient patients
1999
Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia.
1995
Unique efficiency of methionine metabolism in premenopausal women may protect against vascular disease in the reproductive years.
1983
Allantoinases from bacterial, plant and animal sources I. Purification and enzymic properties
1966
149 ESTIMATION OF PYRUVATE DEHYDROGENASE (E1) ACTIVITY IN HUMAN SKELETAL MUSCLE
1986
Disturbed very long chain (C24–C26) fatty acid pattern in fibroblasts of patients with Zellweger's syndrome
1984