F. Somers

Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors

Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders

Ampakines and the threefold path to cognitive enhancement

Glutamate receptor ion channels

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

Quinoxaline, its derivatives and applications: A State of the Art review

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors

Anti-Inflammatory Drugs in the 21st Century

Therapeutic Potential of Positive AMPA Receptor Modulators in the Treatment of Neuropsychiatric Disorders

Overexpression of cyclooxygenase-2 correlates with advanced stages of colorectal cancer

Benzouracil–coumarin–arene conjugates as inhibiting agents for chikungunya virus

Inflammation and Colon Cancer

Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review

Memory enhancement: the search for mechanism-based drugs

4-Thiazolidinone – A biologically active scaffold

Direct transition metal-catalyzed functionalization of heteroaromatic compounds

Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents

Iron Catalysis in Organic Synthesis

Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxidesviathree component SuFEx type reaction

Efficient and highly regioselective direct C-2 arylation of azoles, including free (NH)-imidazole, -benzimidazole and -indole, with aryl halides

Accessing Elaborated 2,1-Borazaronaphthalene Cores Using Photoredox/Nickel Dual-Catalytic Functionalization

1-Oxo-1-fluoro-1,2,4-benzothiadiazines—A new type of cyclic sulfonimidoyl fluorides

SuFEx Chemistry of Thionyl Tetrafluoride (SOF₄) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates

Regiocontrolled Synthesis of 1,2‐Diaryl‐1H‐imidazoles by Palladium‐ and Copper‐Mediated Direct Coupling of 1‐Aryl‐1H‐imidazoles with Aryl Halides under Ligandless Conditions

Environmentally Friendly Iron-Catalyzed Cascade Synthesis of 1,2,4-Benzothiadiazine 1,1-Dioxide and Quinazolinone Derivatives

Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation

Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

Overexpression of cyclooxygenase-2 correlates with advanced stages of colorectal cancer

Copper-Catalyzed Domino Synthesis of Nitrogen Heterocycle-Fused Benzoimidazole and 1,2,4-Benzothiadiazine 1,1-Dioxide Derivatives

The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures

SuFEx Chemistry of Thionyl Tetrafluoride (SOF₄) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates

Iron-catalyzed synthesis of heterocycles

Photoredox Catalysis in Organic Chemistry

Pharmaceuticals that contain polycyclic hydrocarbon scaffolds

Natural Products as Sources of New Drugs from 1981 to 2014

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

Iron-catalyzed oxidative synthesis of N-heterocycles from primary alcohols

Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions

Classification of Chemical Compounds by Protein−Compound Docking for Use in Designing a Focused Library

Prescribed drugs containing nitrogen heterocycles: an overview

Recent Advances in Inducible Cyclooxygenase (COX-2) Inhibition.

Effect onK_ATPChannel Activation Properties and Tissue Selectivity of the Nature of the Substituent in the 7- and the 3-Position of 4H-1,2,4-Benzothiadiazine 1,1-Dioxides

1,4,2-Benzo/pyridodithiazine 1,1-Dioxides Structurally Related to the ATP-Sensitive Potassium Channel Openers 1,2,4-Benzo/pyridothiadiazine 1,1-Dioxides Exert a Myorelaxant Activity Linked to a Distinct Mechanism of Action

Original 2-Alkylamino-6-halogenoquinazolin-4(3H)-ones and K_ATP Channel Activity

Recent Advances in Inducible Cyclooxygenase (COX-2) Inhibition.

Toward Tissue-Selective Pancreatic B-Cells K_ATP Channel Openers Belonging to 3-Alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-Dioxides

Hydroxylated Analogues of ATP-Sensitive Potassium Channel Openers Belonging to the Group of 6- and/or 7-Substituted 3-Isopropylamino-4H-1,2,4-benzothiadiazine 1,1-Dioxides: Toward an Improvement in Sulfonylurea Receptor 1 Selectivity and Metabolism Stability

4H-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4H-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (R/S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors:  Design, Synthesis, Pharmacology, and Structure−Activity Relationships