Citation Impact
Citing Papers
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Stability of person-specific blood-based infrared molecular fingerprints opens up prospects for health monitoring
2021 StandoutNobel
Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains
1991 StandoutNobel
Proton relaxation enhancement by means of serum albumin and poly-l-lysine labeled with DTPA-Gd3+: Relaxivities as a function of molecular weight and conjugation efficiency
1992
By-passing immunization
1991 StandoutNobel
Defining response of ovarian carcinoma to initial chemotherapy according to serum CA 125.
1996
Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
2004
Inference of Macromolecular Assemblies from Crystalline State
2007 Standout
Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
1997 StandoutNobel
Ovarian cancer
2014 Standout
PEO-PPO Block Copolymers for Passive Micellar Targeting and Overcoming Multidrug Resistance in Cancer Therapy
2011
Prodrug Strategies in Anticancer Chemotherapy
2007
Strategies for discovering novel cancer biomarkers through utilization of emerging technologies
2008
Man-made antibodies
1991 NatureNobel
Rationally Designed Chemical Modulators Convert a Bacterial Channel Protein into a pH‐Sensory Valve
2006 StandoutNobel
Selective activation of anticancer prodrugs by monoclonal antibody–enzyme conjugates
2001
Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography
1995
Exploiting altered glycosylation patterns in cancer: Progress and challenges in diagnosis and therapy
1994
Stimuli-responsive nanocarriers for drug delivery
2013 Standout
Novel growth regulatory factors and tumour angiogenesis
1991
Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy
1997
Nanocarriers as an emerging platform for cancer therapy
2007 Standout
Polymeric anticancer drugs with pH-controlled activation
2004
Clinical evidence of efficient tumor targetting based on single–chain Fv antibody selected from a combinatorial library
1996
Glycans in cancer and inflammation — potential for therapeutics and diagnostics
2005 StandoutNobel
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Polymer Therapeutics: Concepts and Applications
2006
Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives
2001
Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars
2009 StandoutNobel
Calmodulin as a Versatile Tag for Antibody Fragments
1995 StandoutNobel
By–Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling
1992 StandoutNobel
Human Antibody Fragments Specific for Human Blood Group Antigens from a Phage Display Library
1993 StandoutNobel
Polymer–drug conjugates: towards a novel approach for the treatment of endrocine-related cancer
2005
Selection of phage antibodies by binding affinity
1992 StandoutNobel
The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops
1992 StandoutNobel
Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy
2007
Design strategies to improve soluble macromolecular delivery constructs
2003
The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT)
1993
Making antibody fragments using phage display libraries
1991 StandoutNatureNobel
Open sandwich ELISA: A novel immunoassay based on the interchain interaction of antibody variable region
1996 StandoutNobel
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Structural and chemical aspects of HPMA copolymers as drug carriers☆
2009
In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells
1992 StandoutNobel
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities
2003
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
The dawning era of polymer therapeutics
2003 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications
1999 Standout
A Radioimmunoassay Using a Monoclonal Antibody to Monitor the Course of Epithelial Ovarian Cancer
1983 Standout
111In-labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-lys(8)-vasotocin: a new powerful radioligand for oxytocin receptor-expressing tumors.
2001
Ligand-Binding Proteins: Their Potential for Application in Systems for Controlled Delivery and Uptake of Ligands
2000
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents.
1994 StandoutNobel
Compact Cysteine-Coated CdSe(ZnCdS) Quantum Dots for in Vivo Applications
2007 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy
1998
Effect of molecular size of pegylated peptide on the pharmacokinetics and tumor targeting in lymphoma-bearing mice.
2003
Bioreducible Block Copolymers Based on Poly(Ethylene Glycol) and Poly(γ-Benzyl l -Glutamate) for Intracellular Delivery of Camptothecin
2011
Making Antibodies by Phage Display Technology
1994 StandoutNobel
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
Synthesis of an organoinsulin molecule that can be activated by antibody catalysis
2001 StandoutNobel
Click Chemistry with O-Dimethylpropargylcarbamate for Preparation of pH-Sensitive Functional Groups. A Case Study
2007
Three-step monoclonal antibody tumor targeting in carcinoembryonic antigen-positive patients.
1991
"Diabodies": small bivalent and bispecific antibody fragments.
1993 StandoutNobel
Pharmacokinetic analysis of two-step approaches using bifunctional and enzyme-conjugated antibodies.
1991
Synthesis of novel targeted pro-prodrugs of anthracyclines potentially activated by a monoclonal antibody galactosidase conjugate (part 1)
1992
Enzyme-Responsive Snap-Top Covered Silica Nanocontainers
2008 StandoutNobel
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
Antibody–Enzyme Fusion Proteins for Cancer Therapy
2011
Molecular Dynamics of Ion−Chelate Complexes Attached to Dendrimers
1996 StandoutNobel
Antibody-directed enzyme prodrug therapy (ADEPT): a review
1997
Multiple biochemical markers in patients with gynecologic malignancies
1980
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Michael addition reactions in macromolecular design for emerging technologies
2006
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies
2016
Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.
1996
Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1
1994 StandoutScience
A cell nanoinjector based on carbon nanotubes
2007 StandoutNobel
Metal–Organic Frameworks for Heterogeneous Basic Catalysis
2017 Standout
Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system.
1992 StandoutNobel
Atomically Precise Clusters of Noble Metals: Emerging Link between Atoms and Nanoparticles
2017 Standout
Works of F Searle being referenced
Operation manual for control of production, preclinical toxicology and phase I trials of anti-tumour antibodies and drug antibody conjugates. Prepared by a Joint Committee of the: Cancer Research Campaign National Institute for Biological Standards and Control
1986
Markers in gynaecological cancer
1980
Disposition of the prodrug 4-(bis (2-chloroethyl) amino) benzoyl-L-glutamic acid and its active parent drug in mice
1990
Ablation of human choriocarcinoma xenografts in nude mice by antibody-directed enzyme prodrug therapy (ADEPT) with three novel compounds
1991
Altered biodistribution of an antibody-enzyme conjugate modified with polyethylene glycol
1996
Repeated antitumour antibody therapy in man with suppression of the host response by cyclosporin A
1988
Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2
1990
Antibody distribution and dosimetry in patients receiving radiolabelled antibody therapy for colorectal cancer
1989
A cytotoxic agent can be generated selectively at cancer sites
1988
Polymer–drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic
2001
N-(2-Hydroxypropyl)methacrylamide Copolymer−6-(3-Aminopropyl)-ellipticine Conjugates. Synthesis, in Vitro, and Preliminary in Vivo Evaluation
2001
β‐HUMAN CHORIONIC GONADOTROPHIN AND CARCINO‐EMBRYONIC ANTIGEN IN THE MANAGEMENT OF OVARIAN CARCINOMA
1977
An efficient method for labelling antibodies with 111In
1984
LIPOSOMALLY ENTRAPPED SECOND ANTIBODY IMPROVES TUMOUR IMAGING WITH RADIOLABELLED (FIRST) ANTITUMOUR ANTIBODY
1982
A human choriocarcinoma xenograft in nude mice, a model for the study of antibody localization
1981