Citation Impact
Citing Papers
The Corticosteroid Receptor Hypothesis of Depression
2000 Standout
Glucocorticoid receptor activation in the rat nucleus of the solitary tract facilitates memory consolidation: involvement of the basolateral amygdala
1999
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist
1999 Standout
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
Steroid Hormones, Receptors, and Antagonists
1996
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Autophagy as a cell death and tumor suppressor mechanism
2004 Standout
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
In vitro and in vivo biologic evaluation of long‐circulating biodegradable drug carriers loaded with the pure antiestrogen RU 58668
2003
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
The antioxidant action of a pure antioestrogen: Ability to inhibit lipid peroxidation compared to tamoxifen and 17β-oestradiol and relevance to its anticancer potential
1994
Stimuli-responsive nanocarriers for drug delivery
2013 Standout
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
2006 Standout
Four deaths and a funeral: from caspases to alternative mechanisms
2001 Standout
Polyester-Poly(Ethylene Glycol) Nanoparticles Loaded with the Pure Antiestrogen RU 58668: Physicochemical and Opsonization Properties
2003
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Similarities and distinctions in the mode of action of different classes of antioestrogens.
2000
Antiestrogen-resistant human breast cancer cells require activated Protein Kinase B/Akt for growth
2005
Cyclodextrin-based pharmaceutics: past, present and future
2004 Standout
Modern Synthetic Methods for Fluorine‐Substituted Target Molecules
2004 Standout
Molecular basis of agonism and antagonism in the oestrogen receptor
1997 StandoutNature
Autophagy in cell death: an innocent convict?
2005 Standout
Steroid hormone receptors: Many Actors in search of a plot
1995 Standout
Antiestrogens: Mechanisms of action and resistance in breast cancer
1997
Catalytic Asymmetric Torgov Cyclization: A Concise Total Synthesis of (+)‐Estrone
2014 StandoutNobel
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy
1996
Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity
2000 StandoutNobel
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β
1998 Standout
Recent developments in the synthesis of 11β-aryl-estrone derivatives
2003
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
The Complex Role of Estrogens in Inflammation
2007 Standout
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Estrogen Receptors as Therapeutic Targets in Breast Cancer
2008
Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production.
1996
Preliminary experience with pure antiestrogens.
2001
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Physicochemical Characteristics and Preliminary in Vivo Biological Evaluation of Nanocapsules Loaded with siRNA Targeting Estrogen Receptor Alpha
2008
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
1994
Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
2005 Standout
Anti‐Estrogen‐Loaded Superparamagnetic Liposomes for Intracellular Magnetic Targeting and Treatment of Breast Cancer Tumors
2010
Chem-Bioinformatics and QSAR: A Review of QSAR Lacking Positive Hydrophobic Terms
2001 Standout
Basic Guide to the Mechanisms of Antiestrogen Action
1998
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
1999 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Various Phosphorylation Pathways, Depending on Agonist and Antagonist Binding to Endogenous Estrogen Receptor α (ERα), Differentially Affect ERα Extractability, Proteasome-Mediated Stability, and Transcriptional Activity in Human Breast Cancer Cells
2003
Alternative Splicing of the D2Dopamine Receptor Messenger Ribonucleic Acid Is Modulated by Activated Sex Steroid Receptors in the MMQ Prolactin Cell Line1
1998
Original tamoxifen-loaded gels containing cyclodextrins: in situ self-assembling systems for cancer treatment
2004
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
Facile route to ferrocifen, 1-[4-(2-dimethylaminoethoxy)]-1-(phenyl-2-ferrocenyl-but-1-ene), first organometallic analogue of tamoxifen, by the McMurry reaction
1997
Polyfluorinated Ethanes as Versatile Fluorinated C2-Building Blocks for Organic Synthesis
2015
Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules
2006 Standout
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Myocardial ischemia-reperfusion injury in estrogen receptor-α knockout and wild-type mice
2000 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
Brain Corticosteroid Receptor Balance in Health and Disease*
1998 Standout
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
2010 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
THE AMYGDALA MODULATES THE CONSOLIDATION OF MEMORIES OF EMOTIONALLY AROUSING EXPERIENCES
2004 Standout
Redox‐ and pH‐Controlled Mechanized Nanoparticles
2009 StandoutNobel
Fluorine in medicinal chemistry: A review of anti-cancer agents
2006
Applications of Fluorine in Medicinal Chemistry
2015 Standout
The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site
1997
Antiestrogens and Selective Estrogen Receptor Modulators as Multifunctional Medicines. 2. Clinical Considerations and New Agents
2003
Comparative QSAR Analysis of Estrogen Receptor Ligands
1999
Die katalytische asymmetrische Torgov‐Cyclisierung: eine kurze Totalsynthese von (+)‐Estron
2014 StandoutNobel
Advances in Male Contraception
2008
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments
2008 Standout
Works of F. Nique being referenced
RU 58668: Further in vitro and in vivo pharmacological data related to its antitumoral activity
1996
Exploration of the Therapeutic Potential of the Antiestrogen RU 58668 in Breast Cancer Treatment
1995
11β-Amidoalkyl estradiols, a new series of pure antiestrogens
1992
Bone protection by estrens occurs through non–tissue-selective activation of the androgen receptor
2006
RU 58 668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice
1994
General Structure‐Activity Correlations of Antihormones
1995
RU 58668
1995
Steroidal Affinity Labels of the Estrogen Receptor. 3. Estradiol 11β-n-Alkyl Derivatives Bearing a Terminal Electrophilic Group: Antiestrogenic and Cytotoxic Properties
1997
11β-Amidoalkoxyphenyl estradiols, a new series of pure antiestrogens
1994
Steroidal Affinity Labels of the Estrogen Receptor α. 4. Electrophilic 11β-Aryl Derivatives of Estradiol
2000
Design of ligands for the glucocorticoid and progestin receptors
1991