Citation Impact
Citing Papers
Autonomic Nerve Development Contributes to Prostate Cancer Progression
2013 StandoutScience
Emerging Concepts of Guanine Nucleotide-Binding Protein-Coupled Receptor (GPCR) Function and Implications for High Throughput Screening
2007
The modes of action of gallamine
1981
Lobeline and Nicotine Evoke [3H]Overflow from Rat Striatal Slices Preloaded with [3H]Dopamine: Differential Inhibition of Synaptosomal and Vesicular [3H]Dopamine Uptake
1997
Regulation of hypoxia‐inducible factor‐α isoforms and redox state by carotid body neural activity in rats
2014 StandoutNobel
Glutamate receptor ion channels
2005 Standout
Allosteric Modulation of Muscarinic Acetylcholine Receptors
2007
G Protein-Coupled Receptor Allosterism and Complexing
2002
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
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A Novel Mechanism of G Protein-coupled Receptor Functional Selectivity
2008
Functionally Different Agonists Induce Distinct Conformations in the G Protein Coupling Domain of the β2Adrenergic Receptor
2001 StandoutNobel
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
2000 StandoutNature
Effects of Guanine, Inosine, and Xanthine Nucleotides on β2-Adrenergic Receptor/GsInteractions: Evidence for Multiple Receptor Conformations
1999 StandoutNobel
An Organizing Framework for Collective Identity: Articulation and Significance of Multidimensionality.
2004 Standout
Functional Gastroduodenal Disorders
2006 Standout
G protein coupled receptor structure and activation
2006 StandoutNobel
Antecedent- and response-focused emotion regulation: Divergent consequences for experience, expression, and physiology.
1998 Standout
Multilevel integrative analyses of human behavior: Social neuroscience and the complementing nature of social and biological approaches.
2000
Zinc activates damage-sensing TRPA1 ion channels
2009 StandoutNobel
Descending control of pain
2002 Standout
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
Functional importance of cholinergic and purinergic neurotransmission for micturition contraction in the normal, unanaesthetized rat
1993
Non‐cardiac adverse effects of antihistamines (H1‐receptor antagonists)
1999
Allosteric regulation of cloned m1–m5 muscarinic receptor subtypes
1991
Cholinergic Innervation and Muscarinic Receptors in the Human Prostate
2007
Slow excitatory post-synaptic potentials in myenteric AH neurons of the guinea-pig ileum are reduced by the 5-hydroxytrytamine7 receptor antagonist SB 269970
2005
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
Interactions of Alcuronium, TMB-8, and Other Allosteric Ligands with Muscarinic Acetylcholine Receptors: Studies with Chimeric Receptors
2000
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Muscarinic Receptors—Characterization, coupling and function
1993
Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology
2007
Quantifying Ligand Bias at Seven-Transmembrane Receptors
2011 StandoutNobel
The neurobiology of zinc in health and disease
2005 Standout
The insulin receptor: a prototype for dimeric, allosteric membrane receptors?
2008
Identification of an Allosteric Binding Site for Zn2+on the β2 Adrenergic Receptor
2002 StandoutNobel
How Ligands Illuminate GPCR Molecular Pharmacology
2017
Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands
2007
Site-Directed Mutagenesis Reveals Two Epitopes Involved in the Subtype Selectivity of the Allosteric Interactions of Gallamine at Muscarinic Acetylcholine Receptors
1999
Role of α-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
2003 StandoutNobel
Molecular Dynamics Simulation for All
2018 Standout
Dementia: The neurochemical basis of putative transmitter orientated therapy
1991
Emerging paradigms in GPCR allostery: implications for drug discovery
2013
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
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Positive Cooperativity of Acetylcholine and Other Agonists with Allosteric Ligands on Muscarinic Acetylcholine Receptors
1997
Tau in physiology and pathology
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Allosteric Modulation of β2-Adrenergic Receptor by Zn2+
2002 StandoutNobel
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Nanoparticles functionalised with reversible molecular and supramolecular switches
2010 StandoutNobel
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
Reflex control of immunity
2009 Standout
Treatment of nausea and vomiting: Gaps in our knowledge
2006
Allosteric modulation of muscarinic acetylcholine receptors
1995
Cyclic Vomiting Syndrome in Adults: Clinical Features and Response to Tricyclic Antidepressants
1999
Pharmacokinetic Optimisation of Antiemetic Therapy
1992
Chemotherapy-Induced Nausea and Vomiting
2008 Standout
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Selectivity of Agonists for the Active State of M1 to M4 Muscarinic Receptor Subtypes
2008
Physiology of Chemotherapy-Induced Emesis and Antiemetic Therapy
1997
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
Characterization of Muscarinic Receptor Subtypes That Mediate Antinociception in the Rat Spinal Cord
1997
Involvement of M3 muscarinic receptors of the spinal cord in formalin-induced nociception in mice
2000
Arisugacins, selective acetylcholinesterase inhibitors of microbial origin
1997 StandoutNobel
Tacrine: A pharmacological review
1991
Cholinergic innervation and function in the prostate gland
2002
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
2007
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Structure of the δ-opioid receptor bound to naltrindole
2012 StandoutNatureNobel
International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands
2014
The assessment of antagonist potency under conditions of transient response kinetics
1999
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Pre- and postsynaptic modulation of glycinergic and gabaergic transmission by muscarinic receptors on rat hypoglossal motoneurons in vitro
2004
On the analysis of ligand-directed signaling at G protein-coupled receptors
2008
The inflammatory reflex
2002 StandoutNature
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
2008
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
2002 Standout
Allosteric binding sites on cell-surface receptors: novel targets for drug discovery
2002
Communication of emotions in vocal expression and music performance: Different channels, same code?
2003 Standout
Adenosine 5′‐triphosphate (ATP) is an excitatory cotransmitter with noradrenaline to the smooth muscle of the rat prostate gland
2003
Identification of Orthosteric and Allosteric Site Mutations in M2 Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias
2010
Muscarinic Receptor Subtypes in Human Nasal Mucosa: Characterization, Autoradiographic Localization, and Function In Vitro
1993
Is the R and R* dichotomy real?
1997
Management of Parkinson's disease: An evidence-based review
2002
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Molecular Physiology of P2X Receptors
2002 Standout
‘Inverse agonists’, cooperativity and drug action at benzodiazepine receptors
1986
Fluorescent Pirenzepine Derivatives as Potential Bitopic Ligands of the Human M1 Muscarinic Receptor
2004
A zinc-sensing receptor triggers the release of intracellular Ca 2+ and regulates ion transport
2001
Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity
1998
Autonomic Nervous System Differences among Emotions
1992
Small molecule modulation of Smoothened activity
2002 Standout
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
Functional Differences between Full and Partial Agonists: Evidence for Ligand-Specific Receptor Conformations
2001 StandoutNobel
Pathophysiology of Sleep Apnea
2010 Standout
Allosteric activation of the CaR by l -amino acids
2000 StandoutNobel
The charge carried by single‐channel currents of rat cultured muscle cells in the presence of local anaesthetics.
1983 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
The use of the slowly degradable analog, α,β-methylene ATP, to produce desensitisation of the P2-purinoceptor: Effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder
1982
Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding site
2001
Is the R and R∗ dichotomy real?
1997
International Union of Pharmacology. XVII. Classification of Muscarinic Acetylcholine Receptors
1998
The Oral Neurokinin-1 Antagonist Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial in Patients Receiving High-Dose Cisplatin—The Aprepitant Protocol 052 Study Group
2003 Standout
EFFECTS OF ADENOSINE 5′‐TRIPHOSPHATE (ATP) AND β‐γ‐METHYLENE ATP ON THE RAT URINARY BLADDER
1979
Cyclic vomiting syndrome in adults
2008
Extracellular ATP: effects, sources and fate
1986 Standout
Works of F. Mitchelson being referenced
Pharmacological Agents Affecting Emesis
1992
Binding of the muscarine receptor antagonist heptane-1,7-bis(dimethyl-3′-phthalimidopropyl) ammonium bromide at cholinoceptor sites
1993
Use of a spreadsheet to quantitate the equilibrium binding of an allosteric modulator
1998
Pharmacological analysis of the mode of interaction of McN-A-343 at atrial muscarinic M2 receptors
1997
Kinetic studies of co-operativity at atrial muscarinic m2 receptors with an “infinite dilution” procedure
1997
Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices
1990
Muscarinic receptor differentiation
1988
Pharmacological Agents Affecting Emesis
1992
[3H]‐Mesulergine labels 5‐HT7 sites in rat brain and guinea‐pig ileum but not rat jejunum
1999
Multiple binding sites for nicotine receptor antagonists in inhibiting [3H](−)-nicotine binding in rat cortex
1993
Interactions of agonists with an allosteric antagonist at muscarinic acetylcholine M2 receptors
1996
Characterization of the subtype selectivity of the allosteric modulator heptane-1,7-bis-(dimethyl-3′-phthalimidopropyl) ammonium bromide (c7/3-phth) at cloned muscarinic acetylcholine receptors
1999
The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies
2000
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria
2001
ALLOSTERIC INTERACTIONS AT MUSCARINIC CHOLINOCEPTORS
1998
SELECTIVE INHIBITION OF RESPONSES TO CARBACHOL AND McN‐A‐343 IN THE RABBIT VAS DEFERENS
1990
Cholinergic facilitation of neurotransmission to the smooth muscle of the guinea‐pig prostate gland
2000
Prejunctional muscarine receptors in the rabbit ear artery differ from M1, M2 and M3 muscarine receptors
1992
The effect of indomethacin and adenosine 5′-triphosphate on the excitatory innervation of the rat urinary bladder
1980
The interaction of McN-A-343 with pirenzepine and other selective muscarine receptor antagonists at a prejunctional muscarine receptor
1985
Comparison of the affinity constant of some muscarinic receptor antagonists with their displacement of [3 H]quinuclidinyl benzilate binding in atrial and ileal longitudinal muscle of the guinea-pig
1985
Interaction of some muscarinic agonists and antagonists at the prejunctional muscarinic receptor in the rabbit ear artery preparation
1986
THE INHIBITORY EFFECT OF GALLAMINE ON MUSCARINIC RECEPTORS
1976
Three Allosteric Modulators Act at a Common Site, Distinct from that of Competitive Antagonists, at Muscarinic Acetylcholine M2 Receptors
1997
The affinity of some selective muscarinic receptor antagonists for the muscarinic receptor mediating endothelial-dependent relaxation of the rabbit and rat thoracic aorta
1986
The role of prostaglandins in the excitatory innervation of the rat urinary bladder
1977
Cellular Signaling Mechanisms for Muscarinic Acetylcholine Receptors
2003
Application of an Allosteric Ternary Complex Model to the Technique of Pharmacological Resultant Analysis
1997
Assessment of the allosteric interactions of the bisquaternary heptane-1,7-bis(dimethyl-3'-phthalimidopropyl)ammonium bromide at M1 and M2 muscarine receptors.
1994