Standout Papers
Citation Impact
Citing Papers
Increased group II phospholipase A2 in colonic mucosa of patients with Crohn's disease and ulcerative colitis.
1994
Lysyl Oxidase Binds Transforming Growth Factor-; and Regulates Its Signaling via Amine Oxidase Activity
2008
Pharmacology of LY315920/S-5920, [[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1 H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A2Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI
1999
The Synthesis of Cystine Peptides by Iodine Oxidation of S‐Trityl‐cysteine and S‐Acetamidomethyl‐cysteine Peptides
1980
Low-dose hydrocortisone infusion attenuates the systemic inflammatory response syndrome
1994
The structure of 2Zn pig insulin crystals at 1.5 Å resolution
1988
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
1994 StandoutNature
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
Group II phospholipase A2 mRNA synthesis is stimulated by two distinct mechanisms in rat vascular smooth muscle cells
1990
Interleukin-1-induced cyclooxygenase 2 expression is suppressed by cyclosporin A in rat mesangial cells
1994
Proteins regulating Ras and its relatives
1993 StandoutNature
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Measurement of arachidonic acid release from human polymorphonuclear neutrophils and platelets: Comparison between gas chromatographic and radiometric assays
1991
Phosphorylation of Munc-18/n-Sec1/rbSec1 by Protein Kinase C
1996 StandoutNobel
Gene Expression of Group Ii Phospholipase A2 in Intestine in Crohn's Disease
1999
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Arachidonic acid in cell signaling
1993
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
1997 Standout
Biaryl diacid inhibitors of human s-PLA2 with anti-inflammatory activity
2000
The Effect of Irbesartan on the Development of Diabetic Nephropathy in Patients with Type 2 Diabetes
2001 Standout
Phospholipase A2 expression in tumours: a target for therapeutic intervention?
2003
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Inhibition of the complete set of mammalian secreted phospholipases A2 by indole analogues
2004
Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy
2001 Standout
Glucocorticoid deficiency increases phospholipase A2 activity in rats.
1993
Anti-inflammatory actions of steroids: molecular mechanisms
1993
Inhibition of Ca2+‐independent phospholipase A2 by bromoenol lactone attenuates prostaglandin generation induced by interleukin‐1β and dibutyryl cAMP in rat mesangial cells
1998
Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate.
1996
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Eicosanoid generation from antigen‐primed mast cells by extracellular mammalian 14‐kDa group II phospholipase A2
1991
3‐(3,5‐Dimethyl‐4‐octadecanoylpyrrol‐2‐yl)propionic Acids as Inhibitors of 85 kDa Cytosolic Phospholipase A2
1996
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1994 StandoutNature
Purification and characterization of rabbit platelet cytosolic phospholipase A2
1991
Synaptotagmin–Syntaxin Interaction: The C2 Domain as a Ca2+-Dependent Electrostatic Switch
1997 StandoutNobel
PLA2 (group IIA phospholipase A2) as a prognostic determinant in stage II colorectal carcinoma
2009
Antibacterial actions of secreted phospholipases A2. Review
2008
Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms
1999
Central nervous system control of food intake
2000 StandoutNature
3‐(Octadecanoylaminomethyl)indole‐2‐carboxylic Acid Derivatives and 1‐Methyl‐3‐octadecanoylindole‐2‐carboxylic Acid as Inhibitors of Cytosolic Phospholipase A2
1996
Expression of Group IIA Secretory Phospholipase A2 Is Elevated in Prostatic Intraepithelial Neoplasia and Adenocarcinoma
2002
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
2001 StandoutNobel
Asthma
2001 Standout
Bactericidal Group IIA Phospholipase A2 in Serum of Patients with Bacterial Infections
2002
C2-domains, Structure and Function of a Universal Ca2+-binding Domain
1998 StandoutNobel
Secretory phospholipase A2 of group IIA: Is it an offensive or a defensive player during atherosclerosis and other inflammatory diseases?
2005
Sickle-cell disease
2010 Standout
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
Diketopiperazines in peptide and combinatorial chemistry
2003
β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice
2009 StandoutNobel
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 Standout
The psychoneuroendocrinology of diabetes mellitus in rodents
1989
Groups IV, V, and X Phospholipases A2s in Human Neutrophils
2002
Roles of secretory phospholipases A2 in inflammatory diseases and trauma
2000
Prostaglandin synthase 2
1996 Standout
The multifunctional or moonlighting protein CD26/DPPIV
2003
The TNF and TNF Receptor Superfamilies
2001 Standout
Analysis of expression of secreted phospholipases A2 in mouse tissues at protein and mRNA levels
2006
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Group II phospholipase A2 in human male reproductive organs and genital tumors
1998
Phospholipase A2 enzymes
2002
cPLA2 is phosphorylated and activated by MAP kinase
1993 Standout
Enhanced expression of group II phospholipase A2 gene in the tissues of endotoxin shock rats and its suppression by glucocorticoid
1990
Roles of Group IIA Phospholipase A2 and Complement in Killing of Bacteria by Acute Phase Serum
2005
Bacterial cell membrane hydrolysis by secreted phospholipases A2: a major physiological role of human group IIa sPLA2 involving both bacterial cell wall penetration and interfacial catalysis
2000
Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock
2002 Standout
Mechanisms of Action of Glucocorticoids in Asthma
1996
E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
2004 StandoutNobel
Oxidative damage and mitochondrial decay in aging.
1994 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes
1994
Prostaglandin synthase-mediated metabolism of carcinogens and a potential role for peroxyl radicals as reactive intermediates.
1990
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
Macrophage-Expressed Group IIA Secretory Phospholipase A 2 Increases Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice
2003
Structures of Free and Inhibited Human Secretory Phospholipase A 2 from Inflammatory Exudate
1991 Science
Dynamin I is a Ca(2+)-sensitive phospholipid-binding protein with very high affinity for protein kinase C.
1994 StandoutNobel
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Structure−Activity Relationships of (4-Acylpyrrol-2-yl)alkanoic Acids as Inhibitors of the Cytosolic Phospholipase A2: Variation of the Substituents in Positions 1, 3, and 5
1997
Phospholipase A2 levels in acute chest syndrome of sickle cell disease
1996
Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition
2004
Bipartite Ca 2+ -Binding Motif in C 2 Domains of Synaptotagmin and Protein Kinase C
1996 StandoutScienceNobel
Synthesis, Biological Evaluation, and Structure−Activity Relationships of 3-Acylindole-2-carboxylic Acids as Inhibitors of the Cytosolic Phospholipase A2
1997
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Protection by Group II Phospholipase A2 Against Staphylococcus aureus
1999
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion
1993
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Interleukin-1 alpha induces the accumulation of cytosolic phospholipase A2 and the release of prostaglandin E2 in human fibroblasts.
1992
Glucocorticoids suppress group II phospholipase A2 production by blocking mRNA synthesis and post-transcriptional expression.
1990
Mechanisms of Diabetic Complications
2013 Standout
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
1993 StandoutNobel
Biosynthesis and Mode of Action of Lantibiotics
2005
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.
1992
Interfacial Enzymology: The Secreted Phospholipase A2-Paradigm
2001
Secretory Phospholipase A 2 Is the Principal Bactericide for Staphylococci and Other Gram-Positive Bacteria in Human Tears
1998
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS
1999
The Molecular Biology of Axon Guidance
1996 StandoutScience
Segregated Coupling of Phospholipases A2, Cyclooxygenases, and Terminal Prostanoid Synthases in Different Phases of Prostanoid Biosynthesis in Rat Peritoneal Macrophages
1998
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression
1991
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Structure-activity relationship studies on (4-acylpyrrol-2-yl)alkanoic acids as inhibitors of the cytosolic phospholipase A2: Variation of the alkanoic acid substituent, the acyl chain and the position of the pyrrole nitrogen
1997
Luminescent pH sensors based on di(2,2′-bipyridyl)(5,5′-diaminomethyl-2,2′-bipyridyl)-ruthenium(II ) complexes
1992
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Novel Syntheses of Tetrahydropyrroloquinolines: Applications to Alkaloid Synthesis
1996
Group II PLA(2) content of tears in normal subjects.
2001
Beneficial Effect of Intravenous Dexamethasone in Children With Mild to Moderately Severe Acute Chest Syndrome Complicating Sickle Cell Disease
1998
Works of F. Märki being referenced
Differential inhibition of human secretory and cytosolic phospholipase A2
1993
Purification, Analysis, and Enzymatic Activity of Recombinant Human Synovial Fluid Phospholipase A2 and N-Terminal Variants
1992
PDGF suppresses the activation of group II phospholipase A2gene expression by interleukin I and forskolin in mesangial cells
1991
Cytokine regulation of Group II phospholipase A2 expression in glomerular mesangial cells
1993
Cytokine-and forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by dexamethasone
1991
Interleukin 1 and tumor necrosis factor synergistically stimulate prostaglandin synthesis and phospholipase A2 release from rat renal mesangial cells
1989
Mode of action of the lanthionine-containing peptide antibiotics duramycin, duramycin B and C, and cinnamycin as indirect inhibitors of phospholipase A2
1991
The Induction of Cellular Group II Phospholipase A2 by Cytokines and its Prevention by Dexamethasone
1992
Release of phospholipase A2 activity from rat vascular smooth muscle cells mediated by cAMP
1989
Transforming growth factors type‐β and dexamethasone attenuate group II phospholipase A2 gene expression by interleukin‐1 and forskolin in rat mesangial cells
1992
Interleukin-1β, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells
1991
DEHYDROBUFOTENINE, A NOVEL TYPE OF TRICYCLIC SEROTONIN METABOLITE FROM Bufo Marinus
1961
Synthesis and Biological Activity of Two Disulphide Bond Isomers of Human Insulin: [A7-A11 ,A6-B7-Cystine]- and [A6-A7,A11-B7-Cystine]insulin (Human)
1978
Interleukin-1 beta- and forskolin-induced synthesis and secretion of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by transforming growth factor-beta 2.
1992
Immunochemical Detection of Group I and Group II Phospholipases A2 in Human Serum
1992
Duramycins B and C, two new lanthionine containing antibiotics as inhibitors of phospholipase A2. Structural revision of duramycin and cinnamycin.
1990
Synthesis and Biological Activity of Seventeen Analogues of Human Insulin
1979
Studies on the acyl-chain selectivity of cellular phospholipases A2
1990
Synovial type (group II) phospholipase A2 in cartilage.
1993
A new class of inhibitors of secretory phospholipase A2: enolized 1,3-dioxane-4,6-dione-5-carboxamides
1994
Role of the Adrenals in the Development of Streptozotocin (STR)-Induced Diabetes in Male Albino Rats
2008
Cyclic AMP mimics, but does not mediate, interleukin-1- and tumour-necrosis-factor-stimulated phospholipase A2 secretion from rat renal mesangial cells
1991
Synthesis and biological activity of five d-Cys analogs of human insulin
1979
Transforming growth factor β2 differentially modulates interleukin-1 β- and tumour-necrosis-factor-α-stimulated phospholipase A2 and prostaglandin E2 synthesis in rat renal mesangial cells
1990
Susceptibility of interleukin 1- and tumour necrosis factor-induced prostaglandin E2 and phospholipase A2 release from rat renal mesangial cells to different drugs
1989
Stability of Endogenous Immunoreactive Glucagon (IRG) in Animal Blood
1983
Endogenous suppression of neutral-active and calcium-dependent phospholipase A2 in human polymorphonuclear leukocytes
1986