Citation Impact
Citing Papers
2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy
2014 Standout
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity
2002
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines
2007 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Transthyretin: a multifaceted protein
2014
Mechanism of Action and Clinical Application of Tafamidis in Hereditary Transthyretin Amyloidosis
2016
Molecular Imaging of Amyloidosis: Will the Heart Be the Next Target After the Brain?
2011
Identification of a novel ligand binding motif in the transthyretin channel
2009
Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors
2013
Inclusion body myositis and myopathies
1995 Standout
The Systemic Amyloidoses
1997 Standout
Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants
2004
Rational design of potent human transthyretin amyloid disease inhibitors.
2000
Amyloid Heart Disease
2010
Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma
2009
Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidogenesis
2006
HRS Expert Consensus Statement on the Diagnosis and Management of Arrhythmias Associated With Cardiac Sarcoidosis
2014 Standout
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin
2010
Diagnosis and Management of Cardiac Sarcoidosis
2010
Sarcoidosis
2013 Standout
Familial amyloid polyneuropathy
2011
Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses
2010
Guideline of transthyretin-related hereditary amyloidosis for clinicians
2013 Standout
Linking tumor cell cytotoxicity to mechanism of drug action: An integrated analysis of gene expression, small‐molecule screening and structural databases
2005
Systemic amyloidosis
2015 Standout
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
HYPERTROPHIC AND RESTRICTIVE CARDIOMYOPATHIES THE ELDERLY
1999
Phenotypic and genotypic heterogeneity in transthyretin-related cardiac amyloidosis: Towards tailoring of therapeutic strategies?
2006
Review: Amyloidogenesis—Unquestioned Answers and Unanswered Questions
2000
The Amyloid State of Proteins in Human Diseases
2012 Standout
The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug
2012
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Benzoxazoles as Transthyretin Amyloid Fibril Inhibitors: Synthesis, Evaluation, and Mechanism of Action
2003
Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies
2010
Design, synthesis, and evaluation of oxazole transthyretin amyloidogenesis inhibitors
2005
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
The systemic amyloidoses: clearer understanding of the molecular mechanisms offers hope for more effective therapies
2004
Pulsed tissue Doppler and strain imaging discloses early signs of infiltrative cardiac disease: A study on patients with familial amyloidotic polyneuropathy
2005
The amyloid state and its association with protein misfolding diseases
2014 Standout
Molecular Mechanisms of Amyloidosis
2003 Standout
Misdiagnosis of Hereditary Amyloidosis as AL (Primary) Amyloidosis
2002
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography
2010 Standout
Serum Amyloid A Regulates Granulomatous Inflammation in Sarcoidosis through Toll-like Receptor-2
2009
Transthyretin-related amyloidoses and the heart: a clinical overview
2010
A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity
2009
Amyloidosis and the Heart
2006
Disease profile and differential diagnosis of hereditary transthyretin-related amyloidosis with exclusively cardiac phenotype: an Italian perspective
2012
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue
2019 Standout
Diagnosis and Management of the Cardiac Amyloidoses
2005
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
Protein Misfolding, Functional Amyloid, and Human Disease
2006 Standout
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Light and heat control over secondary structure and amyloid-like fiber formation in an overcrowded-alkene-modified Trp zipper
2015 StandoutNobel
Transthyretin-derived senile systemic amyloidosis: clinicopathologic and structural considerations
2003
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture
2004
The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis
2001
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
2012
Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis
2005
Schwefel(VI)‐fluorid‐Austausch (SuFEx): Eine weitere gute Anwendung für die Click‐Chemie
2014 StandoutNobel
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
2015 Standout
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
A primer of amyloid nomenclature
2007
Quantification of the Thermodynamically Linked Quaternary and Tertiary Structural Stabilities of Transthyretin and Its Disease-Associated Variants: The Relationship between Stability and Amyloidosis
2008
The Genetics of the Amyloidoses
2000
Transthyretin Cardiac Amyloidoses in Older North Americans
2012
Toward Optimization of the Linker Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies
2008
Inhibiting transthyretin conformational changes that lead to amyloid fibril formation
1998
Transthyretin (TTR) Cardiac Amyloidosis
2012
Toward Optimization of the Second Aryl Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies
2009
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity
2011
Biochemical and Structural Evaluation of Highly Selective 2-Arylbenzoxazole-Based Transthyretin Amyloidogenesis Inhibitors
2007
Partitioning Conformational Intermediates between Competing Refolding and Aggregation Pathways: Insights into Transthyretin Amyloid Disease
2005
Outcomes of Restrictive Cardiomyopathy in Childhood and the Influence of Phenotype
2012
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Bisaryloxime Ethers as Potent Inhibitors of Transthyretin Amyloid Fibril Formation
2005 StandoutNobel
Quantification of Myocardial Extracellular Volume Fraction in Systemic AL Amyloidosis
2012
Evaluating the binding selectivity of transthyretin amyloid fibril inhibitors in blood plasma
2001
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Trapping of palindromic ligands within native transthyretin prevents amyloid formation
2010
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Inclusion-body myositis
2006
99m Tc-Pyrophosphate Scintigraphy for Differentiating Light-Chain Cardiac Amyloidosis From the Transthyretin-Related Familial and Senile Cardiac Amyloidoses
2013
Genetic Biomarkers in Hypertrophic Cardiomyopathy
2013
Works of F Buck being referenced
Variant-Sequence Transthyretin (Isoleucine 122) in Late-Onset Cardiac Amyloidosis in Black Americans
1997
Sarcoidosis and amyloidosis. Is the association causal or co-incidental?
1987