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Citing Papers
2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults
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Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
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Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
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Analyses of Group III Secreted Phospholipase A2 Transgenic Mice Reveal Potential Participation of This Enzyme in Plasma Lipoprotein Modification, Macrophage Foam Cell Formation, and Atherosclerosis
2008
A simple assay for a human serum phospholipase A2 that is associated with high-density lipoproteins
2001
Identification of a Domain That Mediates Association of Platelet-activating Factor Acetylhydrolase with High Density Lipoprotein
2008
The emerging roles of PAF acetylhydrolase
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Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations
2011
Role of macrophage scavenger receptors in atherosclerosis
2012
Phospholipase A2 subclasses in acute respiratory distress syndrome
2009
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
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Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48−/−Lepob/obmice devoid of ApoE or Ldlr
2007
Thiazolidinediones
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Abdominal obesity and metabolic syndrome
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Effects of intravenous apolipoprotein A-I/phosphatidylcholine discs on paraoxonase and platelet-activating factor acetylhydrolase in human plasma and tissue fluid
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Expression of secretory phospholipase A2s in human atherosclerosis development
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Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women
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Paraoxonase 1 and platelet-activating factor acetylhydrolase activities in patients with low hdl-cholesterol levels with or without primary hypertriglyceridemia
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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
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Mechanisms linking obesity with cardiovascular disease
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Platelet-Activating Factor (PAF): Signalling and Adhesion in Cell-Cell Interactions
1996
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system
2002
Conversion of alkylacetylglycerol to platelet-activating factor in HL-60 cells and subcellular localization of the mediator
1990
Intracellular localization of platelet-activating factor synthesis in human neutrophils
1988
Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
2006
The metabolic syndrome
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Phospholipase A2s: Developing drug targets for atherosclerosis
2010
Macrophages in the Pathogenesis of Atherosclerosis
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Τhe role of lipoprotein-associated phospholipase A2 in atherosclerosis may depend on its lipoprotein carrier in plasma
2009
Lipoprotein modification by secretory phospholipase A2 enzymes contributes to the initiation and progression of atherosclerosis
2009
The changing landscape of atherosclerosis
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Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-containing lipoproteins
2003
Plasma platelet activating factor-acetylhydrolase (PAF-AH)
2003
Macrophages in atherosclerosis: a dynamic balance
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Very low density lipoproteins provide a vector for secretion of paraoxonase-1 from cells
2004
Future Role for Selective Phospholipase A2 Inhibitors in the Prevention of Atherosclerotic Cardiovascular Disease
2009
Follicular B helper T cells in antibody responses and autoimmunity
2005
Scavenger receptor family proteins: roles for atherosclerosis, host defence and disorders of the central nervous system
1998
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Antioxidants and Atherosclerotic Heart Disease
1997 Standout
Paraoxonase, a cardioprotective enzyme: continuing issues
2004
Protection against Oxidative Stress-induced Hepatic Injury by Intracellular Type II Platelet-activating Factor Acetylhydrolase by Metabolism of Oxidized Phospholipids in Vivo
2007
Bioactive products generated by Group V sPLA2 hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines
2010
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials
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Subcellular localization of phospholipids and enzymes involved in PAF‐acether metabolism
1989
Cell regulation by sphingosine and more complex sphingolipids
1991
The importance of high-density lipoproteins for paraoxonase-1 secretion, stability, and activity
2004
Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.
1995
Mammalian platelet-activating factor acetylhydrolases
1996
Update on strategies to increase HDL quantity and function
2009
Age-related decrease in high-density lipoproteins antioxidant activity is due to an alteration in the PON1's free sulfhydyl groups
2005
Secretory phospholipase A2 of group IIA: Is it an offensive or a defensive player during atherosclerosis and other inflammatory diseases?
2005
Hypoxia of the Renal Medulla — Its Implications for Disease
1995 Standout
Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase
2002
Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
1991 Standout
EMT: 2016
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Macrophage Secretory Phospholipase A2 Group X Enhances Anti-inflammatory Responses, Promotes Lipid Accumulation, and Contributes to Aberrant Lung Pathology
2008
Lipoprotein-Associated Phospholipase A2: An Independent Predictor of Coronary Artery Disease Events in Primary and Secondary Prevention
2008
Atherosclerosis — An Inflammatory Disease
1999 Standout
Inhibition of lipoprotein‐associated phospholipase A2 diminishes the death‐inducing effects of oxidised LDL on human monocyte‐macrophages
2001
Blockade of arachidonic acid incorporation into phospholipids induces apoptosis in U937 promonocytic cells
2005
Origin and physiological roles of inflammation
2008 StandoutNature
Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
2000
Membrane lipid composition differentially modulates the function of human plasma platelet activating factor-acetylhydrolase
2010
The Effect of Darapladib on Plasma Lipoprotein-Associated Phospholipase A2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent
2008
Antiatherothrombotic Properties of Statins
1998
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Secretory phospholipase A2: A multifaceted family of proatherogenic enzymes
2009
Plasma C-reactive protein in subjects with hypo/hyperalphalipoproteinemias
2003
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Atherosclerosis
2000 StandoutNature
Phospholipase A2inhibitors as potential therapeutic agents for the treatment of inflammatory diseases
2009
Production and effects of platelet-activating factor in the rat brain
1988
Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
2008 Standout
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
2011 Standout
C-Reactive Protein and Other Emerging Blood Biomarkers to Optimize Risk Stratification of Vulnerable Patients
2006
Matrix metalloproteinases A review of their structure and role in acute coronary syndrome
2003
Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase
2008
Biology of Platelet-activating Factor Acetylhydrolase (PAF-AH, Lipoprotein Associated Phospholipase A2)
2008
Atherosclerosis
2001 Standout
Release of Free F2-isoprostanes from Esterified Phospholipids Is Catalyzed by Intracellular and Plasma Platelet-activating Factor Acetylhydrolases
2005
Platelet-activating Factor Acetylhydrolase, and Not Paraoxonase-1, Is the Oxidized Phospholipid Hydrolase of High Density Lipoprotein Particles
2003
Bifidobacteria can protect from enteropathogenic infection through production of acetate
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Cardiac Remodeling in Obesity
2008
Neurosensory mechanotransduction
2008 StandoutNobel
Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis
2006 Standout
HDL and arteriosclerosis: beyond reverse cholesterol transport
2002
Platelet activating factor inhibits Cl and K transport in the medullary thick ascending limb
1992
Stimulated neutrophils produce an ethanolamine plasmalogen analog of platelet-activating factor.
1987
Modulation of platelet-activating factor (PAF) synthesis and release from human polymorphonuclear leukocytes (PMN): Role of extracellular albumin
1985
Endothelial Protection by High-Density Lipoproteins
2003
High-Density Lipoproteins Retard the Progression of Atherosclerosis and Favorably Remodel Lesions Without Suppressing Indices of Inflammation or Oxidation
2004
Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies
2010
Small, Dense HDL Particles Exert Potent Protection of Atherogenic LDL Against Oxidative Stress
2003
Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
2008
Ether-phospholipid composition in neutrophile and platelets
1985
Antioxidative Activity of HDL Particle Subspecies Is Impaired in Hyperalphalipoproteinemia: Relevance of Enzymatic and Physicochemical Properties
2004
Oxidized Lipids in Atherogenesis: Formation, Destruction and Action
1997
Decreased Protection by HDL From Poorly Controlled Type 2 Diabetic Subjects Against LDL Oxidation May Be Due to the Abnormal Composition of HDL
1999
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques
2004
Macrophage-Expressed Group IIA Secretory Phospholipase A 2 Increases Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice
2003
Myocardial Fatty Acid Metabolism in Health and Disease
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Relationship between Adipocyte Size and Adipokine Expression and Secretion
2006
Compromised LCAT Function Is Associated With Increased Atherosclerosis
2005
Purification of a phospholipase A2 from human monocytic leukemic U937 cells. Calcium-dependent activation and membrane association.
1990
Platelet-activating factor.
1990 Standout
Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions
1999
Cooperation Between Secretory Phospholipase A 2 and TNF-Receptor Superfamily Signaling
2002
Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex.
1990
Modulation of acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PAF) acetyltransferase in human polymorphonuclears. The role of cyclic AMP-dependent and phospholipid sensitive, calcium-dependent protein kinases.
1988
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Platelet-Activating Factor Acetylhydrolases: Broad Substrate Specificity and Lipoprotein Binding Does Not Modulate the Catalytic Properties of the Plasma Enzyme
2001
Platelet-activating Factor Acetylhydrolase Increases during Macrophage Differentiation
1989
The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis
2010
Functional Consequences of Mutations and Polymorphisms in the Coding Region of the PAF Acetylhydrolase (PAF-AH) Gene
2009
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
2009 StandoutNobel
Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition
2004
Pleiotropic Actions of Peroxisome Proliferator–Activated Receptors in Lipid Metabolism and Atherosclerosis
2002
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Role of Na+/H+ exchange in thrombin-induced platelet-activating factor production by human endothelial cells.
1988
Human macrophages secret platelet-activating factor acetylhydrolase.
1990
Lipoprotein-Associated and Secreted Phospholipases A 2 in Cardiovascular Disease
2010
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Desensitization of turkey erythrocyte adenylate cyclase. Beta-adrenergic receptor phosphorylation is correlated with attenuation of adenylate cyclase activity.
1984 StandoutNobel
HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF‐κB activation in smooth muscle cells
2003
Inflammation and Atherosclerosis
2002 Standout
Human type II phospholipase A2-induced Mac-1 expression on human neutrophils
1996
REDD2 Gene Is Upregulated by Modified LDL or Hypoxia and Mediates Human Macrophage Cell Death
2004
1-O-alkyl-linked glycerophospholipids of human neutrophils: distribution of arachidonate and other acyl residues in the ether-linked and diacyl species.
1984
Lipoprotein-Associated Phospholipase A2 Predicts 5-Year Cardiac Mortality Independently of Established Risk Factors and Adds Prognostic Information in Patients with Low and Medium High-Sensitivity C-Reactive Protein (The Ludwigshafen Risk and Cardiovascular Health Study)
2007
The Yin and Yang of Oxidation in the Development of the Fatty Streak
1996 Standout
Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression
2011
Altered distribution of platelet-activating factor-acetylhydrolase activity between LDL and HDL as a function of the severity of hypercholesterolemia
2002
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice
2010
The Val279Phe Variant of the Lipoprotein-Associated Phospholipase A2 Gene Is Associated with Catalytic Activities and Cardiovascular Disease in Korean Men
2006
The Metabolic Syndrome, Circulating Oxidized LDL, and Risk of Myocardial Infarction in Well-Functioning Elderly People in the Health, Aging, and Body Composition Cohort
2004
The final step in the de novo biosynthesis of platelet-activating factor. Properties of a unique CDP-choline:1-alkyl-2-acetyl-sn-glycerol choline-phosphotransferase in microsomes from the renal inner medulla of rats.
1987
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Oxidative Stress and Vascular Disease
2004
The Metabolic Syndrome
2008 Standout
Platelet-Activating Factor Acetylhydrolase Is Mainly Associated With Electronegative Low-Density Lipoprotein Subfraction
2003
Regulation of platelet activating factor synthesis: Modulation of 1-alkyl-2-lyso-sn-glycero-3-phosphocholine:Acetyl-CoA acetyltransferase by phosphorylation and dephosphorylation in rat spleen microsomes
1984
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
2009 Standout
Lipoprotein-Associated Phospholipase A2 Activity Is a Marker of Small, Dense LDL Particles in Human Plasma
2005
Chemokines in Children With Heterozygous Familiar Hypercholesterolemia
2005
Platelet-Activating Factor and Related Lipid Mediators
2000
Atheroprotective Effects of High-Density Lipoproteins
2003
Platelet-activating factor may act as a second messenger in the release of icosanoids and superoxide anions from leukocytes and endothelial cells.
1990
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells
2003
Local Expression of Platelet-Activating Factor-Acetylhydrolase Reduces Accumulation of Oxidized Lipoproteins and Inhibits Inflammation, Shear Stress-Induced Thrombosis, and Neointima Formation in Balloon-Injured Carotid Arteries in Nonhyperlipidemic Rabbits
2005
High Affinity, Stability, and Lactonase Activity of Serum Paraoxonase PON1 Anchored on HDL with ApoA-I
2005
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
HDL Cholesterol and Protective Factors in Atherosclerosis
2004
Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion.
1990
Platelet-Activating Factor Acetylhydrolase Activity Indicates Angiographic Coronary Artery Disease Independently of Systemic Inflammation and Other Risk Factors
2005
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Calmodulin antagonists inhibit formation of platelet-activating factor in stimulated human neutrophils
1984
Human Apolipoprotein A-II Enrichment Displaces Paraoxonase From HDL and Impairs Its Antioxidant Properties
2004
Nuclear Factor κB Signaling in Atherogenesis
2005
Role of Lipoprotein-Associated Phospholipase A 2 in Atherosclerosis
2005
Lipoprotein-Associated Phospholipase A2 (Lp-PLA2): A Novel and Promising Biomarker for Cardiovascular Risks Assessment
2013
Diversity of G Proteins in Signal Transduction
1991 StandoutScience
Works of Ewa Ninio being referenced
Molecular and functional characterization of polymorphisms in the secreted phospholipase A2 group X gene: relevance to coronary artery disease
2009
Platelet-activating factor acetylhydrolase and transacetylase activities in human aorta and mammary artery
2008
N-linked glycosylation of macrophage-derived PAF-AH is a major determinant of enzyme association with plasma HDL
2001
Modification of LDL with human secretory phospholipase A2 or sphingomyelinase promotes its arachidonic acid-releasing propensity
2004
Cell adhesion by membrane-bound paf-acether
1991
Heterogeneity of arachidonate and paf-acether precursor pools in mast cells
1992
Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis
2003
Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus
2006
Oxidized low-density lipoprotein and peroxisome-proliferator-activated receptor α down-regulate platelet-activating-factor receptor expression in human macrophages
2001
Platelet‐associated and secreted PAF‐acetylhydrolase activity in patients with stable angina: sequential changes of the enzyme activity after angioplasty
2001
Extracellular phospholipases in atherosclerosis
2010
Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein
2001
The proinflammatory mediator Platelet Activating Factor is an effective substrate for human group X secreted phospholipase A2
2006
Platelet-activating factor-acetylhydrolase and PAF-receptor gene haplotypes in relation to future cardiovascular event in patients with coronary artery disease
2004
Circulating levels of secretory- and lipoprotein-associated phospholipase A2 activities: relation to atherosclerotic plaques and future all-cause mortality
2012
Plasma PAF-acetylhydrolase: An unfulfilled promise?
2006
Biosynthesis of paf-acether XIV. Paf-acether output in murine peritoneal macrophages is regulated by the level of acetylhydrolase
1989
Oxidized low density lipoproteins downregulate LPS‐induced platelet‐activating factor receptor expression in human monocyte‐derived macrophages
2001
Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: Implication in atherosclerosis
2010
Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women
2009
Pefabloc, 4-[2-aminoethyl]benzenesulfonyl fluoride, is a new, potent nontoxic and irreversible inhibitor of PAF-degrading acetylhydrolase
1996
Phospholipid mediators in the vessel wall: involvement in atherosclerosis
2005
Biosynthesis of Paf-acether (platelet-activating factor). VII. Precursors of Paf-acether and acetyl-transferase activity in human leukocytes.
1984
Effect of Overexpression of Human Apo A-I in C57BL/6 and C57BL/6 Apo E–Deficient Mice on 2 Lipoprotein-Associated Enzymes, Platelet-Activating Factor Acetylhydrolase and Paraoxonase
2000
Antioxidant properties of HDL in transgenic mice overexpressing human apolipoprotein A-II
2002
Is platelet-activating factor (PAF-acether) synthesis by murine peritoneal cells (PC) a two-step process?
1981
Inhibition of LPL Expression in Human Monocyte–Derived Macrophages Is Dependent on LDL Oxidation State
1998
Increased PAFAH and Oxidized Lipids Are Associated With Inflammation and Atherosclerosis in Hypercholesterolemic Pigs
2009
Increased Low-Density Lipoprotein Oxidation and Impaired High-Density Lipoprotein Antioxidant Defense Are Associated With Increased Macrophage Homing and Atherosclerosis in Dyslipidemic Obese Mice
2003
Oxidized low-density lipoprotein and peroxisome-proliferator-activated receptor α down-regulate platelet-activating-factor receptor expression in human macrophages
2001
Copper-Catalyzed Oxidation Mediates PAF Formation in Human LDL Subspecies
1997
Human Platelets Secrete the Plasma Type of Platelet-Activating Factor Acetylhydrolase Primarily Associated With Microparticles
2006
Mildly Oxidized LDL Induces Expression of Group IIa Secretory Phospholipase A 2 in Human Monocyte–Derived Macrophages
2000
HDLassociated PAF‐AH reduces endothelial adhesiveness in apoE −/− mice
2000
Evidence that biosynthesis of platelet‐activating factor (paf‐acether) by human neutrophils occurs in an intracellular membrane
1985
Adenovirus-Mediated Gene Transfer of Human Platelet-Activating Factor–Acetylhydrolase Prevents Injury-Induced Neointima Formation and Reduces Spontaneous Atherosclerosis in Apolipoprotein E–Deficient Mice
2001
Phospholipolyzed LDL induces an inflammatory response in endothelial cells through endoplasmic reticulum stress signaling
2010
Arg123-Tyr166 Domain of Human ApoA-I Is Critical for HDL-Mediated Inhibition of Macrophage Homing and Early Atherosclerosis in Mice
2001
Biosynthesis of paf-acether: VIII: Impairment of paf-acether production in activated macrophages does not depend upon acetyltransferase activity.
1986
Biosynthesis of platelet-activating factor (paf-acether)
1983
Identification on Human CD36 of a Domain (155-183) Implicated in Binding Oxidized Low-Density Lipoproteins (Ox-LDL)
1996
Biosynthesis of platelet-activating factor. VI. Precursor of platelet-activating factor and acetyltransferase activity in isolated rat kidney cells.
1984
Biosynthesis of paf-acether. X. Phorbol myristate acetate-induced paf-acether biosynthesis and acetyltransferase activation in human neutrophils.
1989
Transient activation of the acetyltransferase necessary for paf‐acether biosynthesis in thrombin‐activated platelets
1986
Interleukin-8 Mediates Downregulation of Tissue Inhibitor of Metalloproteinase-1 Expression in Cholesterol-Loaded Human Macrophages
1999
Human platelets release a paf‐acether: Acetylhydrolase similar to that in plasma
1993
Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein
2001
Biosynthesis of platelet-activating factor
1982
PAF-Degrading Acetylhydrolase Is Preferentially Associated With Dense LDL and VHDL-1 in Human Plasma
1995
PAF-acether-degrading acetylhydrolase in plasma LDL is inactivated by copper- and cell-mediated oxidation.
1994
Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function
2006
Weight Loss–Associated Induction of Peroxisome Proliferator–Activated Receptor-α and Peroxisome Proliferator–Activated Receptor-γ Correlate With Reduced Atherosclerosis and Improved Cardiovascular Function in Obese Insulin-Resistant Mice
2004