Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Modular recognition of nucleic acids by PUF, TALE and PPRproteins
2012
Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
2015
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells
2020 StandoutNobel
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
2015 StandoutNobel
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis
2016
QM/MM Methods for Biomolecular Systems
2009 Standout
Epigenetics: A Landscape Takes Shape
2007 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cell-Type-Specific Control of Enhancer Activity by H3K9 Trimethylation
2012
Chromatin Modifications and Their Function
2007 Standout
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
2008
Inhibition of 2-oxoglutarate dependent oxygenases
2011
MLL translocations, histone modifications and leukaemia stem-cell development
2007
Methylation of Lysine 4 on Histone H3: Intricacy of Writing and Reading a Single Epigenetic Mark
2007
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Histone acetyltransferase complexes: one size doesn't fit all
2007
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases
2018
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
2007
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Histone methylation makes its mark on longevity
2011
Modulation of p53 Function by SET8-Mediated Methylation at Lysine 382
2007
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
2008 StandoutNature
Epigenetics in Cancer
2008 Standout
The complex language of chromatin regulation during transcription
2007 StandoutNature
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Hydroxylation mediates chromatin demethylation
2012
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
WD40 proteins propel cellular networks
2010
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Surface enhanced Raman scattering based sensitive detection of histone demethylase activity using a formaldehyde-selective reactive probe
2013
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
2011 StandoutNature
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway
2011 Standout
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
A Trans-tail Histone Code Defined by Monomethylated H4 Lys-20 and H3 Lys-9 Demarcates Distinct Regions of Silent Chromatin
2006
Modular peptide binding: From a comparison of natural binders to designed armadillo repeat proteins
2013
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases
2012
Structural basis of histone H4 recognition by p55
2008
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
2013
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors
2012 StandoutNobel
Ligand binding by repeat proteins: natural and designed
2008
The Hallmarks of Aging
2013 Standout
Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
2011
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
2013 StandoutNobel
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates
2014
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Structural studies on human 2-oxoglutarate dependent oxygenases
2010
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
A General Computational Approach for Repeat Protein Design
2014 StandoutNobel
A Chemical Method for Labeling Lysine Methyltransferase Substrates
2010 StandoutNobel
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
2011 StandoutNobel
Ab Initio Quantum Mechanical/Molecular Mechanical Molecular Dynamics Simulation of Enzyme Catalysis: The Case of Histone Lysine Methyltransferase SET7/9
2007
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins
2010
Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
2012
Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases
2010
Epigenetic Regulation by Histone Demethylases in Hypoxia
2015
Catalytic Mechanism and Product Specificity of the Histone Lysine Methyltransferase SET7/9: An ab Initio QM/MM-FE Study with Multiple Initial Structures
2006
Chromatin and oxygen sensing in the context of JmjC histone demethylases
2014
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
2006
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Specific Electrostatic Molecular Recognition in Water
2016 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity
2007
Works of Evys Collazo being referenced
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase
2007
Purification and assay protocols for obtaining highly active Jumonji C demethylases
2011
Molecular recognition of histone H3 by the WD40 protein WDR5
2006
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
2005
Structural basis for the methylation site specificity of SET7/9
2006