Standout Papers
Citation Impact
Citing Papers
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines
2007 StandoutNobel
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
MicroRNAs Modulate Hematopoietic Lineage Differentiation
2003 StandoutScience
MicroRNA Gene Expression Deregulation in Human Breast Cancer
2005 Standout
Sequence Variations of MicroRNAs in Human Cancer: Alterations in Predicted Secondary Structure Do Not Affect Processing
2006
The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells
2007
Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines
2007 StandoutNobel
A microRNA expression signature of human solid tumors defines cancer gene targets
2006 Standout
MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells
2005 Standout
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival
2004 Standout
miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
A Polycistronic MicroRNA Cluster, miR-17-92 , Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation
2005
Selective Blockade of MicroRNA Processing by Lin28
2008 Science
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
2005
Isothermal amplified detection of DNA and RNA
2014
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
2004 StandoutNobel
Human MicroRNA Targets
2004 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
MicroRNA profiling of the murine hematopoietic system
2005
MicroRNA function in animal development
2005
MicroRNA fingerprints during human megakaryocytopoiesis
2006
Mammalian microRNAs: a small world for fine-tuning gene expression
2006
Expression of Versican 3′-Untranslated Region Modulates Endogenous MicroRNA Functions
2010
MicroRNAs
2004 Standout
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
2009
Wnt/β-catenin pathway represses let-7 microRNAs expression via transactivation of Lin28 to augment breast cancer stem cell expansion
2013
How microRNAs control cell division, differentiation and death
2005
Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
2009
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation
2007
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?
2005
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
MicroRNA expression detected by oligonucleotide microarrays: System establishment and expression profiling in human tissues
2004
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer
2009
MicroRNAs: small RNAs with a big role in gene regulation
2004 Standout
Genotoxicity of Retroviral Integration In Hematopoietic Cells
2006
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Microarray-based, high-throughput gene expression profiling of microRNAs
2004
LNA-modified oligonucleotides mediate specific inhibition of microRNA function
2006
MicroRNA biogenesis: coordinated cropping and dicing
2005 Standout
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs
2004
CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer
2010
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
miR-122, a Mammalian Liver-Specific microRNA, is Processed from hcr mRNA and MayDownregulate the High Affinity Cationic Amino Acid Transporter CAT-1
2004
A high-throughput method to monitor the expression of microRNA precursors
2004
Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines
2006
Widespread microRNA repression by Myc contributes to tumorigenesis
2007
Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications
2008
MicroRNAs as oncogenes
2005
MicroRNA Pathways in Flies and Worms
2003 StandoutNobel
miR‐15a and miR‐16‐1 down‐regulation in pituitary adenomas
2005
An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
2009
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
An elegant miRror: microRNAs in stem cells, developmental timing and cancer
2009
Regulation of miRNA expression during neural cell specification
2005
Reduced expression of Dicer associated with poor prognosis in lung cancer patients
2005
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
2005
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Causes and consequences of microRNA dysregulation in cancer
2009 Standout
Human microRNA prediction through a probabilistic co-learning model of sequence and structure
2005
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Glutamate Signaling in Benign and Malignant Disorders: Current Status, Future Perspectives, and Therapeutic Implications
2013
Oncomirs — microRNAs with a role in cancer
2006 Standout
microRNAs join the p53 network — another piece in the tumour-suppression puzzle
2007
Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression
2008
MicroRNAs in cell proliferation, cell death, and tumorigenesis
2006
Non-coding RNAs in human disease
2011 Standout
The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR
2004
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
2008 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Genomics of microRNA
2006
MicroRNA signatures in human cancers
2006 Standout
A combined computational-experimental approach predicts human microRNA targets
2004
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
2006
miR2Disease: a manually curated database for microRNA deregulation in human disease
2008
BIC and miR‐155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas
2005
Small regulatory RNAs in mammals
2005
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
2006 Standout
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
The microRNA world: small is mighty
2003
MicroRNAs — the micro steering wheel of tumour metastases
2009
A microRNA polycistron as a potential human oncogene
2005 StandoutNature
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
2006 Standout
MicroRNA deregulation in human thyroid papillary carcinomas
2006
Overgrowth caused by misexpression of a microRNA with dispensable wild-type function
2006
Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
2009
Camels and zebrafish, viruses and cancer: a microRNA update
2005
Cancer-related inflammation
2008 StandoutNature
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
2005
Mechanisms of gene silencing by double-stranded RNA
2004 StandoutNature
Tissue-dependent paired expression of miRNAs
2007
mir-29 regulates Mcl-1 protein expression and apoptosis
2007
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Short interfering RNAs as a tool for cancer gene therapy
2004
Biogenesis of small RNAs in animals
2009 Standout
The functions of animal microRNAs
2004 StandoutNatureNobel
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
2004
MicroRNAs in vertebrate development
2005
Chronic Lymphocytic Leukemia
2005
Inference of miRNA targets using evolutionary conservation and pathway analysis
2007
Extensive modulation of a set of microRNAs in primary glioblastoma
2005
MicroRNAs and cancer
2003
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
2010
MicroRNA Biogenesis and Cancer
2005
MicroRNA functions in animal development and human disease
2005
microRNAs exhibit high frequency genomic alterations in human cancer
2006
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
2008 StandoutScienceNobel
MicroRNAs in Cancer
2008
Targeting of microRNAs for therapeutics
2008
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
The role of microRNA genes in papillary thyroid carcinoma
2005 Standout
Let-7 expression defines two differentiation stages of cancer
2007
The Temporal Patterning MicroRNA let-7 Regulates Several Transcription Factors at the Larval to Adult Transition in C. elegans
2005
Sizing up miRNAs as cancer genes
2005
Microarray analysis of microRNA expression in the developing mammalian brain
2004 Nobel
Reduced accumulation of specific microRNAs in colorectal neoplasia.
2003
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
2004
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor
2012
Identification and Characterization of a Novel Gene, C13orf25 , as a Target for 13q31-q32 Amplification in Malignant Lymphoma
2004
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in Eμ-miR155 transgenic mice
2006
Small RNAs: Classification, Biogenesis, and Function
2005
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues
2004
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
2005
let-7 MicroRNA Functions as a Potential Growth Suppressor in Human Colon Cancer Cells
2006
MicroRNA-Cancer Connection: The Beginning of a New Tale
2006
microRNA Functions
2007 Standout
Rapid Alteration of MicroRNA Levels by Histone Deacetylase Inhibition
2006
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
2009 StandoutNobel
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Evan Noch being referenced
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
2002 Standout
Molecular mechanisms of necrosis in glioblastoma: The role of glutamate excitotoxicity
2009
Oncogenic Viruses and Tumor Glucose Metabolism: Like Kids in a Candy Store
2012
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout