Citation Impact
Citing Papers
MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
2009
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
2008 Standout
Biology of Progesterone Receptor Loss in Breast Cancer and Its Implications for Endocrine Therapy
2005
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Modulation of Epidermal Growth Factor Receptor in Endocrine‐Resistant, Estrogen‐Receptor‐Positive Breast Cancer
2002
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Collagen density promotes mammary tumor initiation and progression
2008
Triple-Negative Breast Cancer
2010 Standout
Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer.
2001
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
β-arrestins: traffic cops of cell signaling
2004 StandoutNobel
Membrane Initiated Estrogen Signaling in Breast Cancer1
2006
Adiponectin protects against cerebral ischemia–reperfusion injury through anti-inflammatory action
2009 StandoutNobel
IGF-I mediated survival pathways in normal and malignant cells
2006
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
Diabetic retinopathy
2010 Standout
HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation
2012
Global health burden and needs of transgender populations: a review
2016 Standout
Tumor angiogenesis: molecular pathways and therapeutic targets
2011
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
The GH–IGF-I axis and breast cancer
2003
Insulin-like growth factors and neoplasia
2004
Wnt signaling: is the party in the nucleus?
2006
Pfam: the protein families database
2013 Standout
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Wnt signaling regulates mitochondrial physiology and insulin sensitivity
2010
PET Imaging of CCND1 mRNA in Human MCF7 Estrogen Receptor Positive Breast Cancer Xenografts with Oncogene-Specific [64Cu]Chelator-Peptide Nucleic Acid-IGF1 Analog Radiohybridization Probes
2007
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
2012
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Up-Regulated Expression of Zonula Occludens Protein-1 in Human Melanoma Associates with N-Cadherin and Contributes to Invasion and Adhesion
2005
Unfoldomics of Human Genetic Diseases: Illustrative Examples of Ordered and Intrinsically Disordered Members of the Human Diseasome
2009
Autologous fat transplantation in patients with breast cancer: “silencing” or “fueling” cancer recurrence?
2011
Tight junction proteins
2002
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy
2012 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors
2007
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
A tense situation: forcing tumour progression
2009 Standout
A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism
2017 StandoutNobel
Male breast cancer
2006 Standout
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Collective cell migration in morphogenesis, regeneration and cancer
2009 Standout
Epidemiology of basal-like breast cancer
2007
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
2017 StandoutNobel
The role of insulin receptors and IGF-I receptors in cancer and other diseases
2008
Effects of Insulin-like Growth Factor Binding Protein-3 and Farnesyltransferase Inhibitor SCH66336 on Akt Expression and Apoptosis in Non-Small-Cell Lung Cancer Cells
2004
Insulin Receptor Substrate-1 Associates with Small Nucleolar RNA Which Contributes to Ribosome Biogenesis
2014
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Obesity, metabolic syndrome and esophageal adenocarcinoma: Epidemiology, etiology and new targets
2011
The PI3K Pathway in Human Disease
2017 Standout
The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer
2008
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Insulin‐like growth factor‐I receptor, E‐cadherin and αv integrin form a dynamic complex under the control of α‐catenin
2007
Mitochondria and cancer
2012 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
2014 Standout
Obesity and Eye Diseases
2007
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
2006 Standout
Estrogen rapid action via protein complex formation involving ERα and Src
2005
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
New Roles for β-Arrestins in Cell Signaling: Not Just for Seven-Transmembrane Receptors
2006 StandoutNobel
HypoxamiRs and Cancer: From Biology to Targeted Therapy
2013
Riding the Crest of the Teachable Moment: Promoting Long-Term Health After the Diagnosis of Cancer
2005 Standout
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Obesity and Cancer Mechanisms: Cancer Metabolism
2016
MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia
2011
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
2012 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Novel role for insulin as an autocrine growth factor for malignant brain tumour cells
2007
External imaging of CCND1 cancer gene activity in experimental human breast cancer xenografts with 99mTc-peptide-peptide nucleic acid-peptide chimeras.
2004
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Blockade of Paracrine Supply of Insulin-Like Growth Factors Using Neutralizing Antibodies Suppresses the Liver Metastasis of Human Colorectal Cancers
2005
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
2013 Standout
Pituitary prolactin-secreting macroadenoma combined with bilateral breast cancer in a 45-year-old male
2001
Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis
2008
Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail
2007
BRCA1/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases
2007
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Insulin and Cancer
2003
Crosstalk between Estrogen Receptor and Growth Factor Receptor Pathways as a Cause for Endocrine Therapy Resistance in Breast Cancer
2005
Insulin Induces Heterologous Desensitization of G Protein-Coupled Receptor and Insulin-Like Growth Factor I Signaling by Downregulating β-Arrestin-1
2002
Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
2003 StandoutNobel
Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer
2021 Standout
β-Arrestin-1 Competitively Inhibits Insulin-Induced Ubiquitination and Degradation of Insulin Receptor Substrate 1
2004 StandoutNobel
Lutetium-177 Therapeutic Radiopharmaceuticals: Linking Chemistry, Radiochemistry, and Practical Applications
2015
Mechanistic Pathways of Sex Differences in Cardiovascular Disease
2016
Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases
2008
The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
2007
Signalling pathways of insulin-like growth factors (IGFs) and IGF binding protein-3
2011
Works of Eva Surmacz being referenced
Functional Significance of Type 1 Insulin-like Growth Factor-mediated Nuclear Translocation of the Insulin Receptor Substrate-1 and β-Catenin
2005
IGF-I Receptor-induced Cell-Cell Adhesion of MCF-7 Breast Cancer Cells Requires the Expression of Junction Protein ZO-1
2001
Founder mutations in BRCA1 and BRCA2 genes
2007
Estrogen receptor-α regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells
2003
Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor
2003
BRCA1 genetic testing in 106 breast and ovarian cancer families from southern Italy (Sicily): a mutation analyses
2007
Leptin and cancer
2005
miR‐20b modulates VEGF expression by targeting HIF‐1α and STAT3 in MCF‐7 breast cancer cells
2010
Function of the IGF-I Receptor in Breast Cancer
2000
Retinoic acid mediates degradation of IRS-1 by the ubiquitin–proteasome pathway, via a PKC-dependant mechanism
2004
Nuclear insulin receptor substrate 1 interacts with estrogen receptor α at ERE promoters
2004
Estradiol Increases IRS-1 Gene Expression and Insulin Signaling in Breast Cancer Cells
2001
Role of the IGF‐I receptor in the regulation of cell–cell adhesion: Implications in cancer development and progression
2002
Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer.
2004
Increased Expression of Leptin and the Leptin Receptor as a Marker of Breast Cancer Progression: Possible Role of Obesity-Related Stimuli
2006