Citation Impact
Citing Papers
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage
2015 Standout
Importance of group X–secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model
2007
Identification by Gene Coregulation Mapping of Novel Genes Involved in Embryonic Stem Cell Differentiation
2010
Function, Activity, and Membrane Targeting of Cytosolic Phospholipase A2ζ in Mouse Lung Fibroblasts
2007
A simple assay for a human serum phospholipase A2 that is associated with high-density lipoproteins
2001
Role of Group V Phospholipase A2 in Zymosan-induced Eicosanoid Generation and Vascular Permeability Revealed by Targeted Gene Disruption
2004
Activation of human inflammatory cells by secreted phospholipases A2
2006
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Low-dose hydrocortisone infusion attenuates the systemic inflammatory response syndrome
1994
Human Group V Phospholipase A2 Induces Group IVA Phospholipase A2-independent Cysteinyl Leukotriene Synthesis in Human Eosinophils
2003
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 Å resolution
1991 Nature
Expression of secretory phospholipase A2s in human atherosclerosis development
2007
The role of cytosolic phospholipase A2-alfa in regulation of phagocytic functions
2006
Tetracyclines inhibit activated B cell function
2001
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.
1997 Standout
A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in Mammals
1997
Biology of Secretory Phospholipase A2
2008
Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms
2000 Standout
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Effects of pyrrophenone, an inhibitor of group IVA phospholipase A2, on eicosanoid and PAF biosynthesis in human neutrophils
2006
Biaryl diacid inhibitors of human s-PLA2 with anti-inflammatory activity
2000
Toll-like Receptors and Innate Immunity
2001
Differential hydrolysis of molecular species of lipoprotein phosphatidylcholine by groups IIA, V and X secretory phospholipases A
2005
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
A Randomized Trial of the Efficacy and Tolerability of the COX-2 Inhibitor Rofecoxib vs Ibuprofen in Patients With Osteoarthritis
2000
Role of Group VIA Calcium-independent Phospholipase A2 in Arachidonic Acid Release, Phospholipid Fatty Acid Incorporation, and Apoptosis in U937 Cells Responding to Hydrogen Peroxide
2004
Prostaglandins and sickness behavior: Old story, new insights
2009
Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
2000 Standout
Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target
2007 Nobel
Transglutaminase 2, a Novel Regulator of Eicosanoid Production in Asthma Revealed by Genome-Wide Expression Profiling of Distinct Asthma Phenotypes
2010
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
Mechanism of Inhibition of Human Nonpancreatic Secreted Phospholipase A2 by the Anti-inflammatory Agent BMS-181162*
1995
Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats
2006
Group V Phospholipase A2 Induces Leukotriene Biosynthesis in Human Neutrophils through the Activation of Group IVA Phospholipase A2
2002
Sepsis: a roadmap for future research
2015
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
2008
Benefits and Risks of Minocycline in Rheumatoid Arthritis
2000
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
Selective inhibition of group II phospholipase A2 by quercetin
1993
Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate.
1996
2003
Lung mast cells are a source of secreted phospholipases A2
2009
Intracellular Toll-like Receptors
2010 StandoutNobel
Inflammatory lipid mediators in adipocyte function and obesity
2010
Ether lysophospholipid-induced production of platelet-activating factor in human polymorphonuclear leukocytes
1990
Inactivation of human synovial fluid phospholipase a2 by the marine natural product, manoalide
1990
Crystal Structure of Human Group X Secreted Phospholipase A2
2002
Serum amyloid A, the major vertebrate acute‐phase reactant
1999
Phospholipase A2 — a mediator between proximal and distal effectors of inflammation
1991
Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men
1999
Nitrogen Oxide Levels in Patients After Trauma and During Sepsis
1991
Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2 alpha
2005
Structure-antioxidant activity relationships of flavonoids and phenolic acids
1996 Standout
Antibacterial actions of secreted phospholipases A2. Review
2008
Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms
1999
The immune system in atherosclerosis
2011 Standout
Sepsis and septic shock
2018 Standout
Low-Tidal-Volume Ventilation in the Acute Respiratory Distress Syndrome
2007
Prevention of Peroxynitrite-Dependent Tyrosine Nitration and Inactivation of α1-Antiproteinase by Antibiotics
1997
Receptors for a growing family of secreted phospholipases A2
1999
Bactericidal Group IIA Phospholipase A2 in Serum of Patients with Bacterial Infections
2002
The L-Arginine-Nitric Oxide Pathway
1993 Standout
Secretory phospholipase A2 of group IIA: Is it an offensive or a defensive player during atherosclerosis and other inflammatory diseases?
2005
Tetracyclines: Nonantibiotic properties and their clinical implications
2006
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
Sickle-cell disease
2010 Standout
Role of phospholipase A2 in human acute pancreatitis
1989
Asthma phenotypes: the evolution from clinical to molecular approaches
2012 Standout
Acute Pancreatitis
1994 Standout
Phospholipase A2 Modification of Lipoproteins: Potential Effects on Atherogenesis
2002
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2
2002
Enhanced production of platelet-activating factor in stimulated rat leukocytes pretreated with triacsin C, a novel acyl-CoA synthetase inhibitor
1992 StandoutNobel
The Pathophysiology and Treatment of Sepsis
2003 Standout
Age-Related Changes in Bone Morphology Are Accelerated in Group VIA Phospholipase A2 (iPLA2β)-Null Mice
2008
Post‐transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines
1997
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
The immunopathology of sepsis and potential therapeutic targets
2017 Standout
Minocycline in Active Rheumatoid Arthritis
1994
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
2008 Standout
Efficacy and safety of LY315920Na/S-5920, a selective inhibitor of 14-kDa group IIA secretory phospholipase A2, in patients with suspected sepsis and organ failure
2003
Interfacial Kinetic and Binding Properties of Mammalian Group IVB Phospholipase A2 (cPLA2β) and Comparison with the Other cPLA2 Isoforms
2010
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
2001 Standout
Toll-like receptors and innate immunity
2009
A novel anti‐inflammatory role for secretory phospholipase A 2 in immune complex‐mediated arthritis
2010
Analysis of expression of secreted phospholipases A2 in mouse tissues at protein and mRNA levels
2006
Sarcoidosis
2007 Standout
Release of phospholipase A2 activity from rat vascular smooth muscle cells mediated by cAMP
1989
Relationship between levels of secreted phospholipase A2 groups IIA and X in the airways and asthma severity
2011
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Control of adaptive immunity by the innate immune system
2015 Standout
cPLA2 is phosphorylated and activated by MAP kinase
1993 Standout
Roles of Group IIA Phospholipase A2 and Complement in Killing of Bacteria by Acute Phase Serum
2005
Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome
2010 Standout
Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock
2002 Standout
Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations
2015 Standout
Structure and Properties of a Human Non-pancreatic Phospholipase A2
1989
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Toll-Like Receptors
2003 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Design and Synthesis of Phospholipase C and A2-Activatable Near-Infrared Fluorescent Smart Probes
2010
Novel Mammalian Group XII Secreted Phospholipase A2Lacking Enzymatic Activity,
2003
Sulfasalazine
2005
Activation of Cytokine Production by Secreted Phospholipase A2 in Human Lung Macrophages Expressing the M-Type Receptor
2005
Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
2008
Indole Inhibitors of Human Nonpancreatic Secretory Phospholipase A2. 1. Indole-3-acetamides
1996
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators
2013
APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models
2012 StandoutNobel
Adipose Tissue, Inflammation, and Cardiovascular Disease
2005 Standout
Tetracyclines Modulate Protease-Activated Receptor 2-Mediated Proinflammatory Reactions in Epidermal Keratinocytes
2009
Macrophage-Expressed Group IIA Secretory Phospholipase A 2 Increases Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice
2003
Structures of Free and Inhibited Human Secretory Phospholipase A 2 from Inflammatory Exudate
1991 Science
Platelet-activating factor.
1990 Standout
A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers.
2000
Presence of the M-type sPLA2 receptor on neutrophils and its role in elastase release and adhesion
2002
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
In Vivo Protective Role of Human Group IIA Phospholipase A2 against Experimental Anthrax
2005
Phospholipase A2 levels in acute chest syndrome of sickle cell disease
1996
Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome.
1996
Minocycline: far beyond an antibiotic
2013 Standout
Protection by Group II Phospholipase A2 Against Staphylococcus aureus
1999
Role of Group IIa and Group V Secretory Phospholipases A2 in the Metabolism of Lipoproteins. Substrate Specificities of the Enzymes and the Regulation of Their Activities by Sphingomyelin
2002
Diversity of group types, regulation, and function of phospholipase A2.
1994 Standout
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice
2010
Inflammatory Mechanisms in Obesity
2011 Standout
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Secretory Phospholipases A2 Activate Selective Functions in Human Eosinophils
2003
Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis
2011
Indole Inhibitors of Human Nonpancreatic Secretory Phospholipase A2. 3. Indole-3-glyoxamides
1996
Group V and X secretory phospholipase A2 prevents adenoviral infection in mammalian cells
2005
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Antifibrotic Activity of an Inhibitor of Group IIA Secretory Phospholipase A2 in Young Spontaneously Hypertensive Rats
2006
Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization
2005
Tetracyclines Inhibit Connective Tissue Breakdown by Multiple Non-Antimicrobial Mechanisms
1998
Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells
2003
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature
2010
Minocycline as a Neuroprotective Agent
2005
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Neurotoxins Affecting Neuroexocytosis
2000 Standout
Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function
2006
Cloning and Recombinant Expression of Phospholipase A2 Present in Rheumatoid Arthritic Synovial Fluid
1989
The influence of tetracyclines on T cell activation
1995
Works of Eva Stefanski being referenced
Regulation of the cellular expression of secretory and cytosolic phospholipases A2, and cyclooxygenase-2 by peptide growth factors
1998
Mitogenic Effect of Lipoproteins on Human Vascular Smooth Muscle Cells: The Impact of Hydrolysis by gr II A Phospholipase A2
2001
Inhibition of enzymatic activity of phospholipases A2 by minocycline and doxycycline
1992
Extracellular phospholipase A2 secretion is a common effector pathway of interleukin-1 and tumour necrosis factor action
1991
Inhibition of extracellular release of proinflammatory secretory phospholipase A2 (sPLA2) by sulfasalazine
1997
Comparison of group I and II soluble phospholipases A2 activities on phagocytic functions of human polymorphonuclear and mononuclear phagocytes
1991
p38 MAPK Regulates Group IIa Phospholipase A2Expression in Interleukin-1β-stimulated Rat Neonatal Cardiomyocytes
2001
Induction of Secretory Phospholipase A2 Confirms the Systemic Inflammatory Nature of Adjuvant Arthritis
1998
Multiple Forms of Phospholipase A2 in Arthritic Synovial Fluid
1989
c-Jun N-terminal Kinase-mediated Stabilization of Microsomal Prostaglandin E2 Synthase-1 mRNA Regulates Delayed Microsomal Prostaglandin E2 Synthase-1 Expression and Prostaglandin E2 Biosynthesis by Cardiomyocytes
2006
Secretory Non‐Pancreatic Phospholipase A2 and cyclooxygenase‐2 Expression by Tracheobronchial Smooth Muscle Cells
1996
Pathogenesis of hypotension in septic shock
1988
Groups IV, V, and X Phospholipases A2s in Human Neutrophils
2002
Association of hyperphospholipasemia A2 with multiple system organ dysfunction due to salicylate intoxication
1993
Microsomal Prostaglandin E 2 Synthase-1 Deletion Leads to Adverse Left Ventricular Remodeling After Myocardial Infarction
2008
Lipoproteins are substrates for human secretory group IIA phospholipase A2: preferential hydrolysis of acute phase HDL
1998
Interleukin-1α stimulates the release of prostaglandin E2 and phospholipase A2 from fetal rat calvarial cells in vitro: Relationship to bone nodule formation
1991
Purification of a Soluble Phospholipase A2 from Synovial Fluid in Rheumatoid Arthritis1
1986
MAP Kinase Kinase 6–p38 MAP Kinase Signaling Cascade Regulates Cyclooxygenase-2 Expression in Cardiac Myocytes In Vitro and In Vivo
2003