Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
2014
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
2013
Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model
2016
Cancer immunoediting: from immunosurveillance to tumor escape
2002 Standout
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
2011
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
2011 Nature
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
2005 Standout
Efficient T Cell Activation via a Toll-Interleukin 1 Receptor-Independent Pathway
2006 StandoutNobel
Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
2012
Necroptosis and its role in inflammation
2015 StandoutNature
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy
2004
SNIPERs—Hijacking IAP activity to induce protein degradation
2019
From bench to clinic with apoptosis-based therapeutic agents
2000 Nature
Death by TNF: a road to inflammation
2022
Bcl-2 and Bcl-xL Inhibit CD95-mediated Apoptosis by Preventing Mitochondrial Release of Smac/DIABLO and Subsequent Inactivation of X-linked Inhibitor-of-Apoptosis Protein
2002
TNFR1‐induced activation of the classical NF‐κB pathway
2011
Sensitizing Anthrax Lethal Toxin-resistant Macrophages to Lethal Toxin-induced Killing by Tumor Necrosis Factor-α
2003 StandoutNobel
Cancer drug resistance: an evolving paradigm
2013 Standout
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
2010
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
NOD2 and inflammation: current insights
2018
The kiss of death: promises and failures of death receptors and ligands in cancer therapy
2001
The Bcl2 family: regulators of the cellular life-or-death switch
2002 Standout
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
2019 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
2002
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
2002
Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance
2013
Death Receptor Recruitment of Endogenous Caspase-10 and Apoptosis Initiation in the Absence of Caspase-8
2001
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
A long-awaited merger of the pathways mediating host defence and programmed cell death
2014
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
2013
Death receptors in chemotherapy and cancer
2004
Bid Mediates Apoptotic Synergy between Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and DNA Damage
2004
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Integrin inactivators: balancing cellular functions in vitro and in vivo
2013
Emerging roles for Lys11-linked polyubiquitin in cellular regulation
2011
cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
2011
Apo2L/TRAIL and its death and decoy receptors
2003
Proteasome-mediated Degradation of Smac during Apoptosis: XIAP Promotes Smac Ubiquitination in Vitro
2002
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Death receptor signal transducers: nodes of coordination in immune signaling networks
2009
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Regulation of tumour necrosis factor signalling: live or let die
2015
Death and anti-death: tumour resistance to apoptosis
2002 Standout
Linear ubiquitination in NF-κB signaling and inflammation: What we do understand and what we do not
2011
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
2011
Regulated necrosis: disease relevance and therapeutic opportunities
2016
Tumor necrosis factor signaling
2003 Standout
The CD95 Type I/Type II model
2003
RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
2014
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
2011 Nature
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Crosstalk in NF-κB signaling pathways
2011 Standout
Signaling to NF-κB
2004 Standout
Expanding TRAF function: TRAF3 as a tri-faced immune regulator
2011
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 Standout
SHARPIN is an endogenous inhibitor of β1-integrin activation
2011
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
2000 Standout
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy
2003
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
2011
The TNF and TNF Receptor Superfamilies
2001 Standout
Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways
2001
Ferroptosis and Necroptosis in the Kidney
2020
Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells
2013
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
Calreticulin exposure dictates the immunogenicity of cancer cell death
2006 Standout
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
2002
A decade of caspases
2003
Mechanisms of Apoptosis
2000
CD95's deadly mission in the immune system
2000 Nature
Advances in Malignant Mesothelioma
2005 Standout
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Caspase Activation Inhibits Proteasome Function during Apoptosis
2004 StandoutNobel
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
2014
CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells
2007
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
2017 StandoutNobel
Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells
2004 StandoutNobel
Signaling by the TNF Receptor Superfamily and T Cell Homeostasis
2000
Control of Life-or-Death Decisions by RIP1 Kinase
2013
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
2014
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
2013
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway
2005
Caspase-10 is an initiator caspase in death receptor signaling
2001
FLICE-Inhibitory Proteins: Regulators of Death Receptor-Mediated Apoptosis
2001
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
2014
Novel cross-talk within the IKK family controls innate immunity
2011
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas
2011
Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
2014
The Ubiquitin Code
2012 Standout
Antigen-Specific Cytotoxicity by Invariant NKT Cells In Vivo Is CD95/CD178-Dependent and Is Correlated with Antigenic Potency
2010 StandoutNobel
Lymphocyte-Mediated Cytotoxicity
2002
Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis
2018 StandoutNobel
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
2014
Works of Eva Rieser being referenced
HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
2014
FADD/MORT1 and Caspase-8 Are Recruited to TRAIL Receptors 1 and 2 and Are Essential for Apoptosis Mediated by TRAIL Receptor 2
2000
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation
2018
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
2015
Linear ubiquitination prevents inflammation and regulates immune signalling
2011 Nature
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
2018
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
2012
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
2009
TNF-Related Apoptosis-Inducing Ligand Mediates Tumoricidal Activity of Human Monocytes Stimulated by Newcastle Disease Virus
2003