Citation Impact
Citing Papers
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Genome-Wide Mapping of in Vivo Protein-DNA Interactions
2007 StandoutScience
Linkage Map ofEscherichia coliK-12, Edition 10: The Traditional Map
1998
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1996 StandoutNobel
Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.
1991
The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes
1991
PDX-1/VP16 Fusion Protein, Together With NeuroD or Ngn3, Markedly Induces Insulin Gene Transcription and Ameliorates Glucose Tolerance
2005
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Id gene expression during development and molecular cloning of the human Id-1 gene
1995
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
2014
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
2008
HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA
1991 StandoutNobel
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
2002
Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo
1991 Nobel
Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region
1998 StandoutNobel
Inflammation and metabolic disorders
2006 StandoutNature
The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic β cells and intestinal endocrine cells
2006
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
Genetically engineered mouse models of pancreatic adenocarcinoma
2013
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning
1998 StandoutNobel
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
2009 StandoutNobel
The price of repression
1995
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
1994
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
2000
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice
1997
Direct lineage conversions: unnatural but useful?
2011
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein
1993 Standout
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
1993 Standout
Insulinoma-Associated 1 Has a Panneurogenic Role and Promotes the Generation and Expansion of Basal Progenitors in the Developing Mouse Neocortex
2008 StandoutNobel
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
1998 Standout
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Gene regulatory factors in pancreatic development
2003
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
2008 StandoutNature
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
2002
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Expression of Neuronal Traits in Pancreatic Beta Cells
1997
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
2003 Standout
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1
1996 StandoutNobel
Clonal selection and learning in the antibody system
1996 StandoutNature
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
An Olfactory Sensory Map Develops in the Absence of Normal Projection Neurons or GABAergic Interneurons
1998 StandoutNobel
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Selection of single-stranded DNA molecules that bind and inhibit human thrombin
1992 StandoutNature
Quantitative Assessment of Gene Targeting in Vitroand in Vivo by the Pancreatic Transcription Factor, Pdx1
2002
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
2010 StandoutNature
B-Cell- and Myocyte-Specific E2-Box-Binding Factors Contain E12/E47-Like Subunits
1991 Nobel
Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras
2009
Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection
1990 Science
β-Cell Pdx1 Expression Is Essential for the Glucoregulatory, Proliferative, and Cytoprotective Actions of Glucagon-Like Peptide-1
2005
The Insulin Gene Contains Multiple Transcriptional Elements That Respond to Glucose
1994
Circadian oscillations in period gene mRNA levels are transcriptionally regulated.
1992 StandoutNobel
Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc
1991 StandoutScience
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
1996
Glucose-Induced Transcription of the Insulin Gene Is Mediated by Factors Required for β-Cell-Type-Specific Expression
1994
The DNA-binding protein E12 co-operates with XMyoD in the activation of muscle-specific gene expression in Xenopus embryos.
1992 StandoutNobel
Localization of E2A mRNA expression in developing and adult rat tissues.
1993
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas
1997
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Differentiation of Embryonic Stem Cells to Insulin-Secreting Structures Similar to Pancreatic Islets
2001 Science
Xenopus embryos contain a somite-specific, MyoD-like protein that binds to a promoter site required for muscle actin expression.
1991 StandoutNobel
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms
2000
Profound defects in pancreatic β-cell function in mice with combined heterozygous mutations in Pdx-1 , Hnf-1 α, and Hnf-3 β
2002
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.
1992
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor.
1995
Consequences of heteromeric interactions among helix-loop-helix proteins.
1993
Works of Eva Henderson being referenced
Transcription Factor Occupancy of the Insulin Gene in Vivo
2003
Pancreatic β Cell-specific Transcription of thepdx-1 Gene
2000
Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.
1991
c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products
1995
c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of control.
1994
Pancreatic β-Cell-Type-Specific Transcription of the Insulin Gene Is Mediated by Basic Helix-Loop-Helix DNA-Binding Proteins
1991
Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription.
1994
Valine-sensitive acetohydroxy acid synthases in Escherichia coli K-12: Unique regulation modulated by multiple genetic sites
1977
XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor.
1994
Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence.
1990
Hepatocyte Nuclear Factor 3β is Involved in Pancreatic β-Cell-Specific Transcription of the pdx-1 Gene
1997
Identification of a Pancreatic β-Cell Insulin Gene Transcription Factor That Binds to and Appears To Activate Cell-Type-Specific Expression: Its Possible Relationship to Other Cellular Factors That Bind to a Common Insulin Gene Sequence
1990
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
2004
MafB
2006
Functional Characterization of the Transactivation Properties of the PDX-1 Homeodomain Protein
1997