Citation Impact
Citing Papers
Aristolochic acid and the etiology of endemic (Balkan) nephropathy
2007 Standout
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Late Onset of Bladder Urothelial Carcinoma After Kidney Transplantation for End-Stage Aristolochic Acid Nephropathy: A Case Series With 15-Year Follow-up
2008
Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles
2019 Standout
Analytical methods to assess nanoparticle toxicity
2009
Carcinogenic 3-nitrobenzanthrone but not 2-nitrobenzanthrone is metabolised to an unusual mercapturic acid in rats
2011
Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization
2011
Sjögren's syndrome
2005 Standout
Determination of aristolochic acid in Chinese herbal medicine by capillary electrophoresis with laser-induced fluorescence detection
2005
Redox-triggered intracellular dePEGylation based on diselenide-linked polycations for DNA delivery
2013
Removal of synthetic dyes from wastewaters: a review
2004 Standout
For patients taking herbal therapy--lessons from aristolochic acid nephropathy
2007
Acquisition of platinum drug resistance and platinum cross resistance patterns in a panel of human ovarian carcinoma xenografts
1993
Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
2004 StandoutNobel
Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system
2014
DNA adduct formation and oxidative stress from the carcinogenic urban air pollutant 3-nitrobenzanthrone and its isomer 2-nitrobenzanthrone, in vitro and in vivo
2007
Aristolochic Acid and ???Chinese Herbs Nephropathy???
2003
Theoretical investigations on the formation of nitrobenzanthrone-DNA Adducts
2011
Selective Toxicity of Aristolochic Acids I and II
2007
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Mitochondria, Oxidants, and Aging
2005 Standout
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review
2002 Standout
Polymer Therapeutics: Concepts and Applications
2006
The golden age: gold nanoparticles for biomedicine
2011 Standout
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Chinese herbs nephropathy-associated slimming regimen induces tumours in the forestomach but no interstitial nephropathy in rats
1998
Using polymerase arrest to detect DNA binding specificity of aristolochic acid in the mouse H-ras gene
2000
DNA Repair: Enzymatic Mechanisms and Relevance to Drug Response
1996
Chronic kidney disease: global dimension and perspectives
2013 Standout
Transgene-derived hepatocyte growth factor attenuates reactive renal fibrosis in aristolochic acid nephrotoxicity
2003
Oncogenes and signal transduction
1991 Standout
Mechanisms of acquired resistance to cisplatin
1994
Complex reactions catalyzed by cytochrome P450 enzymes
2006
Mutagenicity and DNA Adduct Formation by the Urban Air Pollutant 2-Nitrobenzanthrone
2007
Effects of dexfenfluramine on aristolochic acid nephrotoxicity in a rat model for Chinese-herb nephropathy
2003
Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents
2010
Mutagenic activities and physicochemical properties of selected nitrobenzanthrones
2006
Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles
2008 Standout
DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis
2011
3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence
2005
Potent Mechanism-Based Inhibition of Human CYP2B6 by Clopidogrel and Ticlopidine
2004
DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy
2004
Role of Environmental Toxins in Endemic (Balkan) Nephropathy
2007
Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase
2003
Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing
2007
Aristolochic acid nephropathy: A worldwide problem
2008 Standout
Further studies with a cell immortalization assay to investigate the mutation signature of aristolochic acid in human p53 sequences
2006
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Modulation of cis-diamminedichloroplatinum(II) resistance: a review
1992
QUANTITATIVE DETERMINATION OF ARISTOLOCHIC ACID-DERIVED DNA ADDUCTS IN RATS USING 32P-POSTLABELING/POLYACRYLAMIDE GEL ELECTROPHORESIS ANALYSIS
2006
Therapeutic dose as the point of departure in assessing potential health hazards from drugs in drinking water and recycled municipal wastewater
2010
Structure activity relationships of aristolochic acid analogues: Toxicity in cultured renal epithelial cells
2005
The determination and interpretation of the therapeutic index in drug development
2012
An expedient synthesis of ellipticine via Suzuki–Miyaura coupling
2010
Iron Catalysis in Organic Synthesis
2015 Standout
Synthesis of Ellipticine: A Radical Cascade Protocol to Aryl- and Heteroaryl-Annulated[b]carbazoles
2005
Synthesis of Carbazoles by Intramolecular Arylation of Diarylamide Anions
2009
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Histone Deacetylase Inhibitors as Anticancer Drugs
2017
Metal-free synthesis of benzimidazo[2,1-a]ellipticines via tandem inter and intramolecular cyclization
2011
Synthesis of N-methylcarbazoles from N-(2-iodoaryl)-N-methylanilines in the presence of potassium tert-butoxide and iron(II) bromide
2013
An efficient modification of ellipticine synthesis and preparation of 13-hydroxyellipticine
2007
A one-pot synthetic approach to the functionalized isomeric ellipticine derivatives through an imino Diels–Alder reaction
2009
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
Electro-Fenton Process and Related Electrochemical Technologies Based on Fenton’s Reaction Chemistry
2009 Standout
β-Phenylethylamines and the isoquinoline alkaloids
2004
Quantification of 3-Nitrobenzanthrone-DNA Adducts Using Online Column-Switching HPLC-Electrospray Tandem Mass Spectrometry
2009
Ynamides: A Modern Functional Group for the New Millennium
2010 Standout
Current Status of Platinum-Based Antitumor Drugs
1999 Standout
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Intracellular phospholipases A
1980
Biotransformation of N -Nitrosodimethylamine by Pseudomonas mendocina KR1
2006
The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry
1993 StandoutNobel
Nanoparticles in Photodynamic Therapy
2015 Standout
Localization of phospholipase A2 in normal and ras-transformed cells.
1988
Evaluation of intensive postremission chemotherapy for adults with acute nonlymphocytic leukemia using high-dose cytosine arabinoside with L-asparaginase and amsacrine with etoposide.
1987 StandoutNobel
Visual Detection of Sudan Dyes Based on the Plasmon Resonance Light Scattering Signals of Silver Nanoparticles
2006
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
A rapid and versatile synthesis of novel pyrimido[5,4-b]carbazoles
2009
Regulate to reduce chemical mixture risk
2018 StandoutScience
Chimeric Antigen Receptor Therapy
2018 Standout
Toxic Effects of the Major Components of Diesel Exhaust in Human Alveolar Basal Epithelial Cells (A549)
2016
Antioxidant-induced changes of the AP-1 transcription complex are paralleled by a selective suppression of human papillomavirus transcription
1997 StandoutNobel
CuI/La(OTf)3 catalyzed, one-pot synthesis of isomeric ellipticine derivatives in ionic liquid
2010
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Regulation of microtubule cold stability by calmodulin-dependent and -independent phosphorylation.
1983 StandoutNobel
Science and technology for water purification in the coming decades
2008 StandoutNature
Bepridil and cetiedil. Vasodilators which inhibit Ca2+-dependent calmodulin interactions with erythrocyte membranes.
1984 StandoutNobel
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Regioselective cycloaddition of acetylenic esters: a one-pot synthesis of novel dihydrobenzo[a]carbazoles
2011
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
High-dose cytosine arabinoside therapy for refractory leukemia
1983
Loading of an anti-cancer drug onto graphene oxide and subsequent release to DNA/RNA: a direct optical detection
2013
The cellular production of hydrogen peroxide
1972
Biomedical Importance of Indoles
2013 Standout
Association between human erythrocyte calmodulin and the cytoplasmic surface of human erythrocyte membranes.
1983 StandoutNobel
Synthesis of carbazoles by dehydro Diels–Alder reactions of ynamides
2008
Progressive Interstitial Renal Fibrosis Due to Chinese Herbs in a Patient with Calcinosis Raynaud Esophageal Sclerodactyly Telangiectasia (CREST) Syndrome.
2001
Nitrated Confined Imidodiphosphates Enable a Catalytic Asymmetric Oxa-Pictet–Spengler Reaction
2016 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
1998 Standout
Breast cancer cell-derived matrix supports vascular morphogenesis
2012
Phospholipases as Tools to Study the Localization of Phospholipids in Biological Membranes. A Critical Review
1982
Calmodulin Plays a Pivotal Role in Cellular Regulation
1980 StandoutScience
Aristolochic Acid Nephropathy: The Hong Kong Perspective
2007
Physiology of Microglia
2011 Standout
The Position of Carbon-Carbon Bond Cleavage in the Ribulose Diphosphate Carboxydismutase Reaction
1965 StandoutNobel
Works of Eva Frei being referenced
Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols
2005
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
2007
Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase — 32P-postlabeling analysis of DNA adduct formation
2001
MOLECULAR MECHANISM OF GENOTOXICITY OF THE ENVIRONMENTAL POLLUTANT 3-NITROBENZANTHRONE
2005
Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy
2007
Caffeine-derived N-nitroso compounds IV: kinetics of mononitrosocaffeidine demethylation by rat liver microsomes
1994
DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique
2002
Pharmacokinetics of methotrexate???albumin conjugates in tumor-bearing rats
1997
Analysis of the inhibition of N-nitroso-dimethylamine activation in the liver by N-nitro-dimethylamine using a new non-linear statistical method
1999
Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium
2007
Chemoresistance in rat ovarian tumours
1991
Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy
1999
Covalent binding of the anticancer drug ellipticine to DNA in V79 cells transfected with human cytochrome P450 enzymes
2002
The Synergistic Effects of DNA-Targeted Chemotherapeutics and Histone Deacetylase Inhibitors As Therapeutic Strategies for Cancer Treatment
2012
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12‐hydroxyellipticine and 13‐hydroxyellipticine
2006
Benzenediazonium Ion Derived from Sudan I Forms an 8-(Phenylazo)guanine Adduct in DNA
1995
THE ENVIRONMENTAL POLLUTANT AND CARCINOGEN 3-NITROBENZANTHRONE AND ITS HUMAN METABOLITE 3-AMINOBENZANTHRONE ARE POTENT INDUCERS OF RAT HEPATIC CYTOCHROMES P450 1A1 AND -1A2 AND NAD(P)H:QUINONE OXIDOREDUCTASE
2006
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity
2008
DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling
2003
Development of a novel polyethylene glycol-corticosteroid-conjugate with an acid-cleavable linker
2010
The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts☆
2001
Chloride Influx Provokes Lamellipodium Formation in Microglial Cells
2008
Native albumin for targeted drug delivery
2010
The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells
2009
Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures
1994
Determination of intracellular reduced glutathione and glutathione related enzyme activities in cisplatin-sensitive and resistant experimental ovarian carcinoma cell lines
1989
Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:Cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid‐DNA adducts found in patients with urothelial cancer
2004
Comparative studies on the pharmacokinetics of hydrophilic prolinedithiocarbamate, sarcosinedithiocarbamate and the less hydrophilic diethyldithiocarbamate
1995
MOLECULAR MECHANISMS OF ANTINEOPLASTIC ACTION OF AN ANTICANCER DRUG ELLIPTICINE
2006
Rat Microsomes Activating the Anticancer Drug Ellipticine to Species Covalently Binding to Deoxyguanosine in DNA Are a Suitable Model Mimicking Ellipticine Bioactivation in Humans
2002
Pharmacologic and Cytokinetic Studies of Arabinosyl Cytosine
2015
DNA Adduct Formation by the Anticancer Drug Ellipticine and Its Hydroxy Derivatives in Human Breast Adenocarcinoma MCF-7 Cells
2004
Phospholipase A2 from sheep erythrocyte membrane CA2+ dependence and localization
1979
The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and EllipticineN2-Oxide
2004
Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by NADPH : cytochrome P450 reductase form adducts found in DNA of patients with Chinese herbs nephropathy.
2001
Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.
2002
Serum albumin leads to false-positive results in the XTT and the MTT assay
2007
Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients. Phase I Study Group of the Association for Medical Oncology of the German Cancer Society.
1999
New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen
2002
Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids: Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A2
2001
[Formate oxidation in the liver].
1957
Isotopie‐Effekte bei Formicodehydrogenase, Hydrogenase und Hydrogenlyase aus E. Coli
1957
Oxidation of 3-aminobenzanthrone, a human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone, by cytochromes P450 - similarity between human and rat enzymes.
2009
Isolation of DT-Diaphorase [NAD(P)H Dehydrogenase (Quinone)] from Rat Liver Cytosol: Identification of New Enzyme Substrates, Carcinogenic Aristolochic Acids
2001
The Effect of pH on Peroxidase-Mediated Oxidation of and DNA Adduct Formation by Ellipticine
2006
Mechanisms of the Different DNA Adduct Forming Potentials of the Urban Air Pollutants 2-Nitrobenzanthrone and Carcinogenic 3-Nitrobenzanthrone
2010
Cytochrome P-450 and Peroxidase Oxidize Detoxication Products of Carcinogenic Aristolochic Acids (Aristolactams) to Reactive Metabolites Binding to DNA in vitro
1995