Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
2010
Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility
2005 StandoutScience
Regulation of learning and memory by meningeal immunity: a key role for IL-4
2010
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein
2002 StandoutScience
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter
2006 StandoutNobel
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
Inflammation and Alzheimer's disease
2000 Standout
Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophage-colony-stimulating factor, and IL-3.
1997
Protein kinase D: a family affair
2003
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
2010 Standout
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Finding a way out: lymphocyte egress from lymphoid organs
2007
Homing and cellular traffic in lymph nodes
2003
Chemokines — Chemotactic Cytokines That Mediate Inflammation
1998 Standout
Pathogenesis and therapy of psoriasis
2007 StandoutNature
The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR
2009
Sphingosine 1-Phosphate, a Key Cell Signaling Molecule
2002
The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
2007
Systematic identification of regulatory proteins critical for T-cell activation
2003
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
FTY720: Placebo‐Controlled Study of the Effect on Cardiac Rate and Rhythm in Healthy Subjects
2006
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice
2004
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway
1999 StandoutNobel
FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity
2002
Dissecting fibrosis: therapeutic insights from the small-molecule toolbox
2015
Multiple sclerosis
2008 Standout
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Sphingosine kinases: A novel family of lipid kinases
2002
The Roles of Nuclear Factor of Activated T Cells and Ying-Yang 1 in Activation-induced Expression of the Interferon-γ Promoter in T Cells
1998
Recent Molecular Advances in Mammalian Glutamine Transport
2001
FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function
2004
The development of allergic inflammation
2008 StandoutNature
Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment
2003
Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules
2009
Cloning and Characterization of a Protein Kinase A Anchoring Protein (AKAP)-related Protein That Interacts with and Regulates Sphingosine Kinase 1 Activity
2002
Asthma
2001 Standout
A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer
2003
FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system
2009
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Chemokine regulation of naıve T cell traffic in health and disease
2003
Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study
2003
Gene expression of the GATA-3 transcription factor is increased in atopic asthma
1999
Ras and relatives—job sharing and networking keep an old family together
2002
Transcription factors and asthma
1998
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
2010
Alzheimer's Disease
2010 Standout
Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis
2006
Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology
2007
Butyrate Activates the cAMP-Protein Kinase A-cAMP Response Element-Binding Protein Signaling Pathway in Caco-2 Cells ,
2011
The Thymus and Central Tolerance
2000
The Transcription Factor c-Maf Controls the Production of Interleukin-4 but Not Other Th2 Cytokines
1999
New developments in FcεRI regulation, function and inhibition
2007
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?
2010
Lymphoid organ development and cell migration
2003
Metabolic pathways and physiological and pathological significances of lysolipid phosphate mediators
2004
Immunosuppressive Drugs for Kidney Transplantation
2004 Standout
Sphingosine-1-phosphate: an enigmatic signalling lipid
2003 Standout
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
2014 Standout
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family
1998 Nature
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
1998 Standout
Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene
1997
Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation
2004
Brain Penetration of the Oral Immunomodulatory Drug FTY720 and Its Phosphorylation in the Central Nervous System during Experimental Autoimmune Encephalomyelitis: Consequences for Mode of Action in Multiple Sclerosis
2007
Integrated signalling pathways for mast-cell activation
2006 Standout
Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation
2001 StandoutNobel
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
2003
Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity
2016
Oral fingolimod (FTY720) in multiple sclerosis
2009
INFLAMMATION AND ALZHEIMERS DISEASE
2000
Early Activation of Sphingosine Kinase in Mast Cells and Recruitment to FcεRI Are Mediated by Its Interaction with Lyn Kinase
2004
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Expression of NFAT-Family Proteins in Normal Human T Cells
1997
FcεRI-Mediated Induction of TNF-α Gene Expression in the RBL-2H3 Mast Cell Line: Regulation by a Novel NF-κB-Like Nuclear Binding Complex
1998
FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis
2008
Kit and FcϵRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells
2004
CHEMOKINES, SPHINGOSINE-1-PHOSPHATE, AND CELL MIGRATION IN SECONDARY LYMPHOID ORGANS
2004
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Characterization of Murine Sphingosine-1-phosphate Phosphohydrolase
2002
TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
1997 Standout
Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production
1998
B7-H1 (Programmed Death-1 Ligand) on Dendritic Cells Is Involved in the Induction and Maintenance of T Cell Anergy
2003
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
2004 StandoutNobel
Activation‐regulated expression and chemotactic function of sphingosine 1‐phosphate receptors in mouse splenic T cells
2002
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Sphingolipids and the Balancing of Immune Cell Function: Lessons from the Mast Cell
2005
T-Cell Receptor Stimulation Elicits an Early Phase of Activation and a Later Phase of Deactivation of the Transcription Factor NFAT1
1996
Fc epsilonRI-mediated induction of TNF-alpha gene expression in the RBL-2H3 mast cell line: regulation by a novel NF-kappaB-like nuclear binding complex.
1998
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b −/− Pdcd1 −/− mice
2005 StandoutNobel
Transactivation of Sphingosine-1–Phosphate Receptors by FcεRI Triggering Is Required for Normal Mast Cell Degranulation and Chemotaxis
2004
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Sphingosine 1‐phosphate induces Chemotaxis of immature dendritic cells and modulates cytokine‐release in mature human dendritic cells for emergence of Th2 immune responses
2002
A novel modifier of regulatory T cells
2009 StandoutNobel
Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator
2013
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
2006
Cutting Edge: Suppression of T Cell Chemotaxis by Sphingosine 1-Phosphate
2002
Works of Eva E. Prieschl being referenced
A novel splice variant of the transcription factor Nrf1 interacts with the TNF promoter and stimulates transcription
1998
The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors
2002
Sphingolipids and the regulation of the immune response
2002
The Nomenclature of Chemokines
1995
Novel Mode of Interference with Nuclear Factor of Activated T-cells Regulation in T-cells by the Bacterial Metaboliten-Butyrate
2002
Sphingolipids: second messengers, mediators and raft constituents in signaling
2000
The Role of Sphingosine Kinase in the Signaling Initiated at the High-Affinity Receptor for IgE (FcεRI) in Mast Cells
2000
Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF promoter in stimulated mast cells
1998
Common and Distinct Signaling Pathways Mediate the Induction of TNF-α and IL-5 in IgE Plus Antigen-Stimulated Mast Cells
1998
p21ras links Fc epsilon RI to NF-AT family member in mast cells. The AP3-like factor in this cell type is an NF-AT family member.
1995
Glycosphingolipid-Induced Relocation of Lyn and Syk into Detergent-Resistant Membranes Results in Mast Cell Activation
2000
Common and distinct signaling pathways mediate the induction of TNF-alpha and IL-5 in IgE plus antigen-stimulated mast cells.
1998
A novel transiently expressed, integral membrane protein linked to cell activation. Molecular cloning via the rapid degradation signal AUUUA.
1992
The Balance between Sphingosine and Sphingosine-1-Phosphate Is Decisive for Mast Cell Activation after Fc∈ Receptor I Triggering
1999
Characterization of CDw92 as a Member of the Choline Transporter-Like Protein Family Regulated Specifically on Dendritic Cells
2001
A nuclear factor of activated T cell-like transcription factor in mast cells is involved in IL-5 gene regulation after IgE plus antigen stimulation.
1995