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2003
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1998
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2004
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2003
Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock
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2003
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1997
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2003
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1997
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2004
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1996
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2006
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2004
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2001
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1995
Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents
1993 Nobel
The molecular logic of endocannabinoid signalling
2003 Standout
Vasodilator actions of abnormal‐cannabidiol in rat isolated small mesenteric artery
2003
Cannabinoids in the treatment of glaucoma
2002
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2009
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2009
Antinociceptive, behavioural and neuroendocrine effects of CP 55,940 in young rats
2002
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2007
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2003
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2009
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2002
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
2007 Standout
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2003
Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats
2006
THE ACTIVATION OF CANNABINOID RECEPTORS IN STRIATONIGRAL GABAERGIC NEURONS INHIBITED GABA UPTAKE
1997
Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid
2003
Effects of topical anandamides on intraocular pressure in normotensive rabbits
1996
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2001
Complex regional haemodynamic effects of anandamide in conscious rats
2002
Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents
2010
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury
2001 Nature
CB2 cannabinoid receptor-mediated peripheral antinociception
2001
Direct inhibition by cannabinoids of human 5‐HT3A receptors: probable involvement of an allosteric modulatory site
2002
Endocannabinoids and related fatty acid derivatives in pain modulation
2002
Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats
2001
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Effects of perinatal mental disorders on the fetus and child
2014 Standout
Antinociceptive actions of cannabinoids following intraventricular administration in rats
1993
Anandamide transport inhibition by the vanilloid agonist olvanil
1999
Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide
2001
Endocannabinoid-Mediated Control of Synaptic Transmission
2009
Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes
2004
Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview
2002
Role of endocannabinoid system in mental diseases
2004
Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats
2006
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
1995 Standout
Reversal of Δ9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
2002
Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells
2005
The endocannabinoid signalling system: Biochemical aspects
2005
Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats
1995
Endocannabinoid signalling in the blood of patients with schizophrenia.
2003
Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors
1999
Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development
2000
Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ9-tetrahydrocannabinol☆
2010
(—)-Δ9-Tetrahydrocannabinol Antagonizes the Peripheral Cannabinoid Receptor-mediated Inhibition of Adenylyl Cyclase
1996
Functional responses to the cannabinoid agonist WIN 55,212-2 in neonatal rats of both genders: influence of weaning
2004
A cannabinoid mechanism in relapse to cocaine seeking
2001
Endocannabinoids and liver disease – review
2005
Endocannabinoids in the regulation of appetite and body weight
2005
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1998
Cannabinoids and cell fate
2002
Arachidonyl Ethanolamide (Anandamide) Activates the Parvocellular Part of Hypothalamic Paraventricular Nucleus
1997
Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain
2006
Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
2004
Endogenous cannabinoids mediate hypotension after experimental myocardial infarction
2001
Identification and characterisation of a novel splice variant of the human CB1 receptor
2004
Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice
2005
Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?
2005
CB1 cannabinoid receptor‐mediated modulation of food intake in mice
2005
Multiple Mechanisms of Endocannabinoid Response Initiation in Hippocampus
2005
Endocannabinoid system and stress and anxiety responses
2005
Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
2009
Evidence for novel cannabinoid receptors
2005
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2007 Standout
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2002
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2002
Arachidonoylserotonin and Other Novel Inhibitors of Fatty Acid Amide Hydrolase
1998
Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington’s disease
2002
Cannabis, cannabinoids and reproduction
2003
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
Prenatal Stress Increases the Hypothalamo‐Pituitary‐Adrenal Axis Response in Young and Adult Rats
1994
2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1
2000
Increased cannabinoid CB1 receptor binding and activation of GTP‐binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP‐treated marmosets
2001
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2000
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2005
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH)
2005
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2004
Δ9‐Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats
2010
Δ9-tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats
1993
Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation
2003
Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial
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2002
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2005
Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition
1997 Science
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1998
Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid.
2002
The Golden Age of Transfer Hydrogenation
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Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice
1999
Cannabis: pharmacology and toxicology in animals and humans
1996
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
2003
Cannabis: pharmacology and toxicology in animals and humans
1996
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2005
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The neurobiology and evolution of cannabinoid signalling
2001
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
Occurrence and Biosynthesis of Endogenous Cannabinoid Precursor,N-Arachidonoyl Phosphatidylethanolamine, in Rat Brain
1997
Effects of cannabinoids on the anxiety-like response in mice.
2006
Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide.
1995
Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide
2000
Exogenous Anandamide Protects Rat Brain against Acute Neuronal InjuryIn Vivo
2001
Cannabinoid Suppression of Noxious Heat-Evoked Activity in Wide Dynamic Range Neurons in the Lumbar Dorsal Horn of the Rat
1999
Presynaptic Cannabinoid Sensitivity Is a Major Determinant of Depolarization-Induced Retrograde Suppression at Hippocampal Synapses
2002
G Protein-coupled Endothelial Receptor for Atypical Cannabinoid Ligands Modulates a Ca2+-dependent K+ Current
2003
1′,1′-Dimethylheptyl-Δ-8-tetrahydrocannabinol-11-oic Acid: A Novel, Orally Effective Cannabinoid with Analgesic and Anti-inflammatory Properties
1999
Nongenomic Transmission Across Generations of Maternal Behavior and Stress Responses in the Rat
1999 StandoutScience
Endocannabinoids control spasticity in a multiple sclerosis model
2000
Anandamide modulates sleep and memory in rats
1998
Δ9 Tetrahydrocannabinol and cannabidiol alter cytokine production by human immune cells
1998
Role of Endogenous Cannabinoids in Synaptic Signaling
2003
Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion
2001 Standout
Structural Requirements for Binding of Anandamide-Type Compounds to the Brain Cannabinoid Receptor
1997
Mesenteric Vasodilation Mediated by Endothelial Anandamide Receptors
1999
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
Cyclodextrin Drug Carrier Systems
1998 Standout
Novel Analogues of Arachidonylethanolamide (Anandamide): Affinities for the CB1 and CB2 Cannabinoid Receptors and Metabolic Stability
1998
The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen
2004
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.
1993
Substrate Specificity and Stereoselectivity of Rat Brain Microsomal Anandamide Amidohydrolase
1999
Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress
1997 StandoutScience
Inhibitory effects of cannabinoid CB 1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis
2003
Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats
2006
A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels
2006 StandoutNobel
CB1 cannabinoid receptors are involved in neuroprotection via NF-κB inhibition
2005
Sleep modulates cannabinoid receptor 1 expression in the pons of rats
2003
Cannabinoids in health and disease
2007
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway
2004
Stress and development: Behavioral and biological consequences
2001
Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress
1995
The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor.
1994
Increase in aqueous solubility, stability and in vitro corneal permeability of anandamide by hydroxypropyl-β-cyclodextrin
1996
Marijuana and cannabinoid regulation of brain reward circuits
2004
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice
2003
Cannabinoids and the gastrointestinal tract
2001
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
1997
Endocannabinoids and Neuroprotection
2002
The endocannabinoid system and the molecular basis of paralytic ileus in mice
2002
Homeostasis, Stress, Trauma, and Adaptation
1998
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
Cannabidiol-induced lymphopenia does not involve NKT and NK cells.
2009
Effects of Rimonabant on Metabolic Risk Factors in Overweight Patients with Dyslipidemia
2005
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms
2001
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
2001
CB 2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids
2005
Inhibitors of arachidonoyl ethanolamide hydrolysis.
1994
Pharmacology of cannabinoids.
2004
The cannabinoid system and immune modulation
2003
Cannabinoid Receptor Agonists Inhibit Glutamatergic Synaptic Transmission in Rat Hippocampal Cultures
1996
Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
2004
Activation of CB 2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
2003
Cannabinoids for Medical Use
2015 Standout
Jekyll and Hyde: Two Faces of Cannabinoid Signaling in Male and Female Fertility
2006
Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors
2003
Cannabinoids Promote Oligodendrocyte Progenitor Survival: Involvement of Cannabinoid Receptors and Phosphatidylinositol-3 Kinase/Akt Signaling
2002
Design, Synthesis and Biological Evaluation of Novel Arachidonic Acid Derivatives as Highly Potent and Selective Endocannabinoid Transporter Inhibitors
2001
Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing
2005
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN
2003
Cannabinoids as Novel Anti-Inflammatory Drugs
2009
Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and β-Pancreatic Cells and in Obesity and Hyperglycemia
2006
Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus
2000
Tetrahydrocannabinol and endocannabinoids in feeding and appetite
2002
Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration
2003
Localization and Mechanisms of Action of Cannabinoid Receptors at the Glutamatergic Synapses of the Mouse Nucleus Accumbens
2001
Control by the endogenous cannabinoid system of ras oncogene‐dependent tumor growth
2001
Cannabinoid CB2Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains
2003
The Endocannabinoid System and the Brain
2012
Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells
1996
Activation of the Peripheral Endocannabinoid System in Human Obesity
2005
RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning
2008 StandoutNobel
Anandamide, a Natural Ligand for the Peripheral Cannabinoid Receptor Is a Novel Synergistic Growth Factor for Hematopoietic Cells
1997
Peripheral cannabinoid receptor, CB2, regulates bone mass
2006
Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors
2004
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens
2002
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
2001
Are Alkyne Reductions Chemo-, Regio-, and Stereoselective Enough To Provide Pure (Z)-Olefins in Polyfunctionalized Bioactive Molecules?
2012
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
2000
2-Arachidonoylglycerol
2004
Mechanism of action of cannabinoids: how it may lead to treatment of cachexia, emesis, and pain.
2006
Cardiovascular Effects of Anandamide in Anesthetized and Conscious Normotensive and Hypertensive Rats
1997
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes.
1994
Prenatal Stress Induces High Anxiety and Postnatal Handling Induces Low Anxiety in Adult Offspring: Correlation with Stress-Induced Corticosterone Secretion
1997
Works of Ester Fride being referenced
Behavioral Methods in Cannabinoid Research
2006
Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling
2006
Prenatal stress increase anxiety related behavior and alters cerebral lateralization of dopamine activity
1988
Endocannabinoids
1998
Differential response to acute and repeated stress in cannabinoid CB1 receptor knockout newborn and adult mice
2005
Endogenous cannabinoid ligands — chemical and biological studies
1996
Chapter 6 The Endocannabinoid System During Development: Emphasis on Perinatal Events and Delayed Effects
2009
Peripheral, but not central effects of cannabidiol derivatives: Mediation by CB1 and unidentified receptors
2005
Endogenous Cannabinoid Ligands
1996
The endocannabinoid-CB1 receptor system in pre- and postnatal life
2004
Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent
1993
Lipids in Neural Function: Modulationof Behavior by Oral Administration of Endocannabinoids Found in Foods
2001
A novel synthetic, nonpsychoactive cannabinoid acid (HU‐320) with antiinflammatory properties in murine collagen‐induced arthritis
2004
An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity
1998
The endocannabinoid system: function in survival of the embryo, the newborn and the neuron
2002
Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid
1998
Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a “CB3” receptor
2003
Ontogenetic development of the response to anandamide and Δ9-tetrahydrocannabinol in mice
1996
Endocannabinoids in the central nervous system-an overview
2002
Alterations in behavioral and striatal dopamine asymmetries induced by prenatal stress
1989
Critical role of the endogenous cannabinoid system in mouse pup suckling and growth
2001
Anandamides: tolerance and cross-tolerance toΔ9-tetrahydrocannabinol
1995
Towards cannabinoid drugs – revisited
1998
Developmental aspects of anandamide: ontogeny of response and prenatal exposure
1996
Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility
2004
(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only
2004
Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides
1995
Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol.
1995
Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors
2005
Effects of prenatal stress on vulnerability to stress in prepubertal and adult rats
1986
Prenatal stress effects on functional development of the offspring
1988
Endocannabinoids and Their Receptors: Physiology, Pathology and Pharmacology
2007
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB 1 receptor
2001
Are the effects of gestational stress on motor development and cerebellar cholinesterase activity mediated prenatally?
1986
HU-308: A specific agonist for CB 2 , a peripheral cannabinoid receptor
1999
The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.
2004
Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain
2008
Prenatal stress impairs maternal behavior in a conflict situation and reduces hippocampal benzodiazepine receptors
1985
Endocannabinoids and Food Intake: Newborn Suckling and Appetite Regulation in Adulthood
2005
Endogenous and Synthetic Cannabinoids: Recent Advances
1996
Increased interhemispheric coupling of the dopamine systems induced by prenatal stress
1987