Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate
2015 StandoutNobel
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated Gliomas
2012
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Cancer-associated Isocitrate Dehydrogenase Mutations Inactivate NADPH-dependent Reductive Carboxylation
2012
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
DNA methylation age of human tissues and cell types
2013 Standout
S-adenosyl-L-homocysteine hydrolase and methylation disorders: Yeast as a model system
2012
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells
2011
Emerging roles of PKM2 in cell metabolism and cancer progression
2012 StandoutNobel
Amino acid pattern and glutamate metabolism during dehydration stress in the 'resurrection' plant Sporobolus stapfianus: a comparison between desiccation-sensitive and desiccation-tolerant leaves
2007 StandoutNobel
Chapter 3 Carnosine and Its Possible Roles in Nutrition and Health
2009
Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency
2008
On the enigma of carnosine’s anti-ageing actions
2008
A lymphoblast model for IDH2 gain-of-function activity in d-2-hydroxyglutaric aciduria type II: Novel avenues for biochemical and therapeutic studies
2011
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
2010 Standout
GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutants
2004
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Relevance of allosteric conformations and homocarnosine concentration on carnosinase activity
2009
Epigenetics and the environment: emerging patterns and implications
2012 Standout
A guide to immunometabolism for immunologists
2016 Standout
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Otto Warburg's contributions to current concepts of cancer metabolism
2011 Standout
Carnosine and cancer: a perspective
2012
Epigenetics and environmental chemicals
2009
Epigenetics and atherosclerosis
2009
Rapid DNA Methylation Changes after Exposure to Traffic Particles
2009
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation
2012
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Regulation of cancer cell metabolism
2011 Standout
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
2017
Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
2015
The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
2012
Beyond genetics: epigenetic code in chronic kidney disease
2010
Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
2012 Standout
Metabolomics: the apogee of the omics trilogy
2012 Standout
Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1
2014
Carnosine Treatment for Gulf War Illness: A Randomized Controlled Trial
2013
Novel Association of Early Onset Hepatocellular Carcinoma with Transaldolase Deficiency
2013
Oxidative Stress in Cancer
2020 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
D‐2‐hydroxyglutaric acid induces oxidative stress in cerebral cortex of young rats
2003
Transaldolase deficiency in two new patients with a relative mild phenotype
2009
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase‐deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling
2007
Primary brain tumours in adults
2012 Standout
DNA methylation-based biomarkers and the epigenetic clock theory of ageing
2018 Standout
Relationship of impairment induced by intracellular S‐adenosylhomocysteine accumulation with DNA methylation in human umbilical vein endothelial cells treated with 3‐deazaadenosine
2009
IDH1 and IDH2 Mutations in Gliomas
2013
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
New cancer targets emerging from studies of the Von Hippel‐Lindau tumor suppressor protein
2010 StandoutNobel
Epigenetic modifications and human disease
2010 Standout
In Vivo Genetic Selection of Renal Proximal Tubules
2005
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Mitochondria and cancer
2012 Standout
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
2011 StandoutNature
Decline in genomic DNA methylation through aging in a cohort of elderly subjects
2008
Chronic Kidney Disease
2016 Standout
Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency
2010
2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations
2011
Nephrological abnormalities in patients with transaldolase deficiency
2012
Non‐enzymatic glycolysis and pentose phosphate pathway‐like reactions in a plausible A rchean ocean
2014
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
2011 StandoutNobel
The Pentose Phosphate Pathway Is a Metabolic Redox Sensor and Regulates Transcription During the Antioxidant Response
2011
Physiology and Pathophysiology of Carnosine
2013 Standout
Nutrition and Aberrant DNA Methylation Patterns in Atherosclerosis: More than Just Hyperhomocysteinemia? ,
2005
Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria
2010
Transaldolase deficiency: report of 12 new cases and further delineation of the phenotype
2013
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis
2014
Macrophage Polarization
2016 Standout
Hominoid-specific enzyme GLUD2 promotes growth of IDH1 R132H glioma
2014
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans
2012
Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling
2017 Standout
Role of Aldehyde Dehydrogenases in Physiopathological Processes
2019
Isocitrate Dehydrogenase Mutation and (R)-2-Hydroxyglutarate: From Basic Discovery to Therapeutics Development
2017
Bioanalysis of Eukaryotic Organelles
2013
Cancer Genome Landscapes
2013 StandoutScience
Superoxide Ion: Generation and Chemical Implications
2016 Standout
Particulate Matter Air Pollution and Cardiovascular Disease
2010 Standout
Progress in understanding 2‐hydroxyglutaric acidurias
2012
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
2016 Standout
2006
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
2014 Standout
The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: A review
2008
Works of Erwin E. W. Jansen being referenced
A novel, quantitative assay for homocarnosine in cerebrospinal fluid using stable-isotope dilution liquid chromatography–tandem mass spectrometry
2005
Anserine inhibits carnosine degradation but in human serum carnosinase (CN1) is not correlated with histidine dipeptide concentration
2010
IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
2011
Therapeutic relevance of mTOR inhibition in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism
2016
Metabolism of γ-hydroxybutyrate to d-2-hydroxyglutarate in mammals: further evidence for d-2-hydroxyglutarate transhydrogenase
2006
Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency
2004
The difference between rare and exceptionally rare: molecular characterization of ribose 5-phosphate isomerase deficiency
2010
Accumulation of thymidine-derived sugars in thymidine phosphorylase overexpressing cells
2010
Therapeutic Intervention in Mice Deficient for Succinate Semialdehyde Dehydrogenase (γ-Hydroxybutyric Aciduria)
2002
Sedoheptulokinase deficiency due to a 57-kb deletion in cystinosis patients causes urinary accumulation of sedoheptulose: elucidation of theCARKLgene
2008
Liver-Directed Adenoviral Gene Transfer in Murine Succinate Semialdehyde Dehydrogenase Deficiency
2004
Determination of S-Adenosylmethionine and S-Adenosylhomocysteine in Plasma and Cerebrospinal Fluid by Stable-Isotope Dilution Tandem Mass Spectrometry
2000
Quantification of Saccharomyces cerevisiae pentose-phosphate pathway intermediates by LC-MS/MS
2009
Detection of transaldolase deficiency by quantification of novel seven‐carbon chain carbohydrate biomarkers in urine
2007
Intracellular S-adenosylhomocysteine increased levels are associated with DNA hypomethylation in HUVEC
2005
Increased Homocysteine and S-Adenosylhomocysteine Concentrations and DNA Hypomethylation in Vascular Disease
2003
Measurement of Urinary d- and l-2-Hydroxyglutarate Enantiomers by Stable-Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry after Derivatization with Diacetyl-l-Tartaric Anhydride
2004