Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
2007 StandoutScience
The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
2012 Science
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
2004 StandoutScience
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
2016 Science
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
2005 StandoutNature
Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein
2014
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts
1999
The Activation of Glycogen Synthase by Insulin Switches from Kinase Inhibition to Phosphatase Activation during Adipogenesis in 3T3-L1 Cells
1998
AMPK signalling in health and disease
2017
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
1999 StandoutNature
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) Effect on Glucose Production, but Not Energy Metabolism, Is Independent of Hepatic AMPK in Vivo
2014
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
2014
PIK3CA is implicated as an oncogene in ovarian cancer
1999
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
2010
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Oncogenic kinase signalling
2001 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Potential Role of Protein Kinase B in Insulin-induced Glucose Transport, Glycogen Synthesis, and Protein Synthesis
1998
Signalling through the lipid products of phosphoinositide-3-OH kinase
1997 Nature
Insulin Increases the Association of Akt-2 with Glut4-containing Vesicles
1998
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction
2015
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase
2015
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
2009
Dynamic control over cell adhesive properties using molecular-based surface engineering strategies
2009 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Glucose Transporters and Insulin Action — Implications for Insulin Resistance and Diabetes Mellitus
1999
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
AMPK at the Nexus of Energetics and Aging
2014
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs
2015
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth
2008
The microenvironment of the tumour–host interface
2001 StandoutNature
The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
2009
Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
2011
AMPK activation: a therapeutic target for type 2 diabetes?
2014
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
2013
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
A Novel Family of Phosphatidylinositol 4-Kinases Conserved from Yeast to Humans
2001 StandoutNobel
Structural basis of AMPK regulation by small molecule activators
2013
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
2010
Liver Retinol Transporter and Receptor for Serum Retinol-binding Protein (RBP4)
2012
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance
2000
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet
2017
The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
2003
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
The Hallmarks of Aging
2013 Standout
Integrins
2002 Standout
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity
2011
Structure of mammalian AMPK and its regulation by ADP
2011 Nature
AMPK as a Pro-longevity Target
2016
A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis
2014
Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
2008
PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking
1998
AMP-Activated Protein Kinase Induces p53 by Phosphorylating MDMX and Inhibiting Its Activity
2013
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Treatment of nonalcoholic fatty liver disease: role of AMPK
2016
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction
2002
2016
Bone Resorption by Osteoclasts
2000 StandoutScience
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial–mesenchymal transition
2008
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Leptin Signaling in the Central Nervous System and the Periphery
2004
A Convergent Process for the Preparation of Adamantane 11-β-HSD-1 Inhibitors
2008
Exploring and Engineering the Cell Surface Interface
2005 StandoutScience
Understanding Adipocyte Differentiation
1998 Standout
Spermidine in health and disease
2018 StandoutScience
Integrin Signaling
1999 StandoutScience
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Unified Approach to Imidodiphosphate-Type Brønsted Acids with Tunable Confinement and Acidity
2021 StandoutNobel
Regulation of Insulin-Stimulated Glucose Transporter GLUT4 Translocation and Akt Kinase Activity by Ceramide
1998
Diversification of cardiac insulin signaling involves the p85α/β subunits of phosphatidylinositol 3-kinase
2001
1997 StandoutNobel
Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation
1998
Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1.
2000
Insulin signal transduction through protein kinase cascades
1998
Autophagy and Metabolism
2010 StandoutScience
Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators
2015
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
2012
Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt
1997 StandoutScience
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Global Analysis of Protein Activities Using Proteome Chips
2001 StandoutScience
Signal Transduction through MAP Kinase Cascades
1998 Standout
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Requirement of Atypical Protein Kinase Cλ for Insulin Stimulation of Glucose Uptake but Not for Akt Activation in 3T3-L1 Adipocytes
1998
Expression and Regulation of RAB3 Proteins in Osteoclasts and Their Precursors
1999
Works of Ernst U. Frevert being referenced
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
2006
Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase-1 in L6 myotubes
2000
Adamantane 11-β-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction
2006
Overexpression of Protein-tyrosine Phosphatase-1B in Adipocytes Inhibits Insulin-stimulated Phosphoinositide 3-Kinase Activity without Altering Glucose Transport or Akt/Protein Kinase B Activation
2000
Targeting of Constitutively Active Phosphoinositide 3-Kinase to GLUT4-containing Vesicles in 3T3-L1 Adipocytes
1998
Protein kinase C isoforms ɛ, η, δ and ζ in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states
1996
Evidence Against a Direct Effect of Leptin on Glucose Transport in Skeletal Muscle and Adipocytes
1998
Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2
1999
Differential Effects of Constitutively Active Phosphatidylinositol 3-Kinase on Glucose Transport, Glycogen Synthase Activity, and DNA Synthesis in 3T3-L1 Adipocytes
1997