Citation Impact
Citing Papers
Anti-PD-1 Antibody Therapy Potently Enhances the Eradication of Established Tumors By Gene-Modified T Cells
2013
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
2015
Toxicities of chimeric antigen receptor T cells: recognition and management
2016
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
2010 StandoutNobel
Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies
2013
High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
2017
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
2009 StandoutNobel
Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
2010
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
2013 StandoutNobel
The Basic Principles of Chimeric Antigen Receptor Design
2013
T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells
2016
T Cells with a CD4 + CD25 + Regulatory Phenotype Suppress In Vitro Proliferation of Virus-Specific CD8 + T Cells during Chronic Hepatitis C Virus Infection
2005
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition
2013
Defects in the Acquisition of CD8 T Cell Effector Function after Priming with Tumor or Soluble Antigen Can Be Overcome by the Addition of an OX40 Agonist
2007
Chimeric antigen receptor -T cell therapy: Applications and challenges in treatment of allergy and asthma
2019
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence
2017
Hallmarks of Cancer: The Next Generation
2011 Standout
Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification
2019 StandoutNobel
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
CAR-T Cells Inflict Sequential Killing of Multiple Tumor Target Cells
2015
CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia
2015
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
CAR-T cells: the long and winding road to solid tumors
2018
Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids
2018
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
2015
Adoptive T Cell Transfer for Cancer Immunotherapy in the Era of Synthetic Biology
2013
Regulatory T Cells in Cancer
2010
Cytokine release syndrome in cancer immunotherapy with chimeric antigen receptor engineered T cells
2013
The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases
2015
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
2016 StandoutNobel
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas
2018
Engineering lymphocyte subsets: tools, trials and tribulations
2009
Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors
2015
Adoptive immunotherapy for cancer: harnessing the T cell response
2012
Notch regulation of lymphocyte development and function
2004
Notch and the Immune System
2003
Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
2018
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
2011 Standout
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
2009 StandoutNobel
Engineered T cells: the promise and challenges of cancer immunotherapy
2016
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
2017 StandoutNobel
Thymic Commitment of Regulatory T Cells Is a Pathway of TCR-Dependent Selection That Isolates Repertoires Undergoing Positive or Negative Selection
2005
Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors
2013
Programmable synthetic receptors: the next-generation of cell and gene therapies
2024
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
2011
Development and function of CD25+CD4+ regulatory T cells
2004 StandoutNobel
FOXP3+ regulatory T cells in the human immune system
2010 StandoutNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
2016
Driving CAR T-cells forward
2016
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
2014 Standout
Prospects for adoptive immunotherapy of pancreatic cancer using chimeric antigen receptor-engineered T-cells
2015
Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy
2017
An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System
2005 Standout
Chimeric antigen receptor T-cell therapies for lymphoma
2017
Adoptive Immunotherapy for Cancer or Viruses
2014
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Acute Myeloid Leukemia
2015 Standout
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
A new approach to gene therapy using Sleeping Beauty to genetically modify clinical‐grade T cells to target CD 19
2013
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
2012
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
2008 StandoutNobel
Investigational CD33-targeted therapeutics for acute myeloid leukemia
2018
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
2007 StandoutNobel
Cytokine Storm
2020 Standout
CD4+regulatory cells as a potential immunotherapy
2005 StandoutNobel
Tools for translation: non-viral materials for therapeutic mRNA delivery
2017
Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
2018 Standout
Chimeric Antigen Receptor Therapy
2018 Standout
Antibody therapy for acute myeloid leukaemia
2013
OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis
2009
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
Targeting of folate receptor β on acute myeloid leukemia blasts with chimeric antigen receptor–expressing T cells
2015
Going viral: chimeric antigen receptor T‐cell therapy for hematological malignancies
2014
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
2017
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
A Single-Step Chemoenzymatic Reaction for the Construction of Antibody–Cell Conjugates
2018
Targeting claudins in cancer: diagnosis, prognosis and therapy.
2021
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
The Future Is Now: Chimeric Antigen Receptors as New Targeted Therapies for Childhood Cancer
2012
Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus
2005
Epstein Barr virus–specific cytotoxic T lymphocytes expressing the anti-CD30ζ artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease
2007
CAR T cell immunotherapy for human cancer
2018 StandoutScience
MOLECULAR GENETICS OF T CELL DEVELOPMENT
2004
De novo design of protein logic gates
2020 StandoutScienceNobel
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
Works of Eric Yvon being referenced
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells
2003
Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antiviral and Antileukemic Activity
2014
Immunotherapy of Metastatic Melanoma Using Genetically Engineered GD2-Specific T cells
2009
An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies
2010
Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression
2009
GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade
2016
Combinational Targeting Offsets Antigen Escape and Enhances Effector Functions of Adoptively Transferred T Cells in Glioblastoma
2013
Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma
2011
In VitroandIn VivoAntitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL againstCD 33 +
2012
Ex vivo fucosylation of third-party human regulatory T cells enhances anti–graft-versus-host disease potency in vivo
2014
Responses to Human CD40 Ligand/Human Interleukin-2 Autologous Cell Vaccine in Patients with B-Cell Chronic Lymphocytic Leukemia
2005
Molecular transfer of CD40 and OX40 ligands to leukemic human B cells induces expansion of autologous tumor–reactive cytotoxic T lymphocytes
2004
Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis
2005
Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes
2003
Antigen-induced regulatory T cells
2004