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Citing Papers
The Behavior and Significance of Slow‐Binding Enzyme Inhibitors
1988
Chapter 24 Imaging Neuronal Subsets and Other Cell Types in Whole-Mount Drosophila Embryos and Larvae Using Antibody Probes
1994
The bHLH protein Dimmed controls neuroendocrine cell differentiation inDrosophila
2003
Molecular Organization of Drosophila Neuroendocrine Cells by Dimmed
2011 StandoutNobel
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
2017 StandoutNobel
Comparative analysis ofCorazonin‐encoding genes (Crz's) inDrosophilaspecies and functional insights intoCrz‐expressing neurons
2005 StandoutNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Modulation of anxiety through blockade of anandamide hydrolysis
2002 Standout
Amino acids that specify structure through hydrophobic clustering and histidine-aromatic interactions lead to biologically active peptidomimetics
1994
Cell type-specific regulatory sequences control expression of theDrosophila FMRF-NH2 neuropeptide gene
1999
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Neuronal activity triggers calcium waves in hippocampal astrocyte networks
1992
Neuropeptides, amines and amino acids in an elementary insect ganglion: Functional and chemical anatomy of the unfused abdominal ganglion
1996
Peptidomimetics derived from natural products
1993
Functional PDF Signaling in the Drosophila Circadian Neural Circuit Is Gated by Ral A-Dependent Modulation
2016
Infant rat separation is a sensitive test for novel anxiolytics
1991
Fluorescence circadian imaging reveals a PDF-dependent transcriptional regulation of the Drosophila molecular clock
2017 StandoutNobel
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation
2003 Standout
Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
1997 Standout
The Catalytic Asymmetric Abramov Reaction
2014 StandoutNobel
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Neuroanatomical studies of period gene expression in the hawkmoth, Manduca sexta
2002
Inositol trisphosphate and calcium signalling
1993 StandoutNature
A pdf Neuropeptide Gene Mutation and Ablation of PDF Neurons Each Cause Severe Abnormalities of Behavioral Circadian Rhythms in Drosophila
1999 StandoutNobel
Detection of Neuropeptides by lmmunocytochemistry
2003
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Neuropeptides in the nervous system of Drosophila and other insects: multiple roles as neuromodulators and neurohormones
2002
Involvement of granule, basket and stellate neurons but not purkinje or Golgi cells in cerebellar cGMP increases in vivo
1994
Conformational constraints: Nonpeptide β‐turn mimics
1990
Synergies and Coincidence Requirements between NO, cGMP, and Ca2+ in the Induction of Cerebellar Long-Term Depression
1997 StandoutNobel
PHM Is Required for Normal Developmental Transitions and for Biosynthesis of Secretory Peptides in Drosophila
2000
1-Aminocylopropane-1-carboxylic acid derivatives as ligands at the glycine-binding site of the N-methyl-D-aspartate receptor
1998
Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster☆
2001
Three-dimensional structure of the complex of the Rhizopus chinensis carboxyl proteinase and pepstatin at 2.5 .ANG. resolution
1982
Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia
1995
Stereoselective Organic Reactions in Water
2002 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Bioorganometallic Chemistry of Ferrocene
2004 Standout
Asymmetric Synthesis via Acetal Templates. 14.1 Preparation of Enantiomerically Pure (3S,4S)- and (3S,4R)-Statine Derivatives
1987
Non-Peptide Gonadotropin-Releasing Hormone Receptor Antagonists
2008
Chemical trapping of complexes of dihydroxyacetone phosphate with muscle fructose-1,6-bisphosphate aldolase
1985 StandoutNobel
Diastereoselection during 1,2-Addition of the Allylindium Reagent to α-Thia and α-Amino Aldehydes in Aqueous and Organic Solvents
1997
Copper Active Sites in Biology
2014 Standout
Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide
2017
A new mode of cyclic carbamate formation via tert-butyldimethylsilyl carbamate. Stereoselective syntheses of statine and its analogue
1987
Synthetic studies on quinocarcin and its related compounds. 1. Synthesis of enantiomeric pairs of the ABE ring systems of quinocarcin
1994
Efficient synthesis of unsymmetrically disubstituted ferrocenes: towards electrochemical dipeptide-Fc-biosensors
2001
Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila
2010 StandoutNobel
Preparation of peptidic α-hydroxy phosphonates a new class of transition state analog renin inhibitors
1990
Medicinal Chemistry in the Golden Age of Biology: Lessons from Steroid and Peptide Research
1991
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
First synthesis of (1S,2S)- and (1R,2R)-1-amino-2-isopropylcyclobutanecarboxylic acids by asymmetric Strecker reaction from 2-substituted cyclobutanones
2003
Asymmetric Synthesis of α‐Amino Acids and N‐Protected α‐Amino Aldehydes by Addition of Chiral Vinyl Anions to Sulfonylimines
1993
The Calpain System
2003 Standout
The Cation−π Interaction
1997 Standout
Stereoselective addition of lithioethyl acetate to Boc-l-prolinal. A convenient chiral synthetic building block for the pyrrolizidine alkaloid ring system
1986
Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
2002 Standout
The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons
1999 StandoutNobel
Functional tests of enhancer conservation between distantly related species
2003 StandoutNobel
Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex
1997 Standout
Complexes of muscle aldolase in equilibrium with fructose 1,6-bisphosphate
1985 StandoutNobel
Synthesis and Structure−Activity Profiles of A-Homoestranes, the Estratropones
1997
A Field Guide to Foldamers
2001 Standout
Additions of Organometallic Reagents to CN Bonds: Reactivity and Selectivity
1998 Standout
The Design and Properties of N‐Carboxyalkyldipeptide Inhibitors of Angiotensin‐Converting Enzyme
1985
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
The slow-binding and slow, tight-binding inhibition of enzyme-catalysed reactions
1982
Active and Inactive Forms of the Transition-state Analog Protease Inhibitor Leupeptin: Explanation of the Observed Slow Binding of Leupeptin to Cathepsin B and Papain
1989
Spatial and Temporal Expression of theperiodandtimelessGenes in the Developing Nervous System ofDrosophila: Newly Identified Pacemaker Candidates and Novel Features of Clock Gene Product Cycling
1997 StandoutNobel
Strict Reagent Control in the Asymmetric Allylboration of N-TIPS-α-Amino Aldehydes with the B-Allyl-10-TMS-9-borabicyclo[3.3.2]decanes
2008
Chiral synthesis of statine
1985
Studying Enzyme Mechanism by 13 C Nuclear Magnetic Resonance
1984 Science
Synthetic studies of didemnins. II. Approaches to statine diastereomers
1987
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Abnormalities of Male-Specific FRU Protein and Serotonin Expression in the CNS offruitlessMutants inDrosophila
2001 StandoutNobel
The Chemistry of Neutron Capture Therapy
1998 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Light-Directed, Spatially Addressable Parallel Chemical Synthesis
1991 StandoutScience
Low-Molecular-Weight Heparins
1997 Standout
Lipopolysaccharide Endotoxins
2002 Standout
Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids.
1984
Asymmetric Synthesis of 2-Amino Alcohol Derivatives from (S)-α-Amino Aldehydes via Chiral Acetal Templates
1987
Fluoro ketone inhibitors of hydrolytic enzymes
1985
Peptidomimetics for Receptor Ligands—Discovery, Development, and Medical Perspectives
1993
A novel short and efficient asymmetric synthesis of statine analogues
1988
Kinetics of factor Xa inhibition by tissue factor pathway inhibitor.
1993
Stereoselective hydrogenation via dynamic kinetic resolution
1989 StandoutNobel
Chiral Metal Complexes as Discriminating Molecular Catalysts
1990 StandoutScienceNobel
Reduction with Yeast Cells, the Key Step of an Efficient Synthesis of (3S, 4S)‐4‐Amino‐3‐hydroxypentanoic Acids
1988
Existence of nitric oxide synthase in rat hippocampal pyramidal cells.
1994 StandoutNobel
Synthesis and reactivity of N‐protected‐α‐amino aldehydes
2003
Cell type-specific regulation of the Drosophila FMRF-NH 2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor
1998
BINAP: an efficient chiral element for asymmetric catalysis
1990 StandoutNobel
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Novel renin inhibitors containing the amino acid statine
1983 Nature
Excitatory Amino Acid Receptors in Schizophrenia
1993
Synthesis of statine and its analogues by homogeneous asymmetric hydrogenation
1988 StandoutNobel
Works of Eric T. Sun being referenced
TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic properties
2011
Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3)
2012
A review of the in vitro and in vivo neurochemical characterization of the NMDA/PCP/Glycine/Ion channel receptor macrocomplex
1990
1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor
1989
An immunocytochemical study of the FMRFamide neuropeptide gene products in Drosophila
1993
Neuropharmacological characterization of 1-Aminocyclopropane-1-carboxylate and 1-Aminocyclobutane-1-carboxylate, Ligands of the N-Methyl-D-Aspartate-associated Glycine Receptor
1990
ChemInform Abstract: SYNTHESIS OF (3S,4S)‐4‐AMINO‐3‐HYDROXY‐6‐METHYLHEPTANOIC ACID DERIVATIVES. ANALYSIS OF DIASTEREOMERIC PURITY
1979
Amino acids derivatives that stabilize secondary structures of polypeptides--
1982
Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist
2006
Synthesis of (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid derivatives. Analysis of diastereomeric purity
1978
Mechanism of inhibition of pepsin by pepstatin
1980
Synthesis of dideoxy-pepstatin. Mechanism of inhibition of porcine pepsin
1977
Synthesis of analogs of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin
1980