Citation Impact
Citing Papers
Activated Kras, but Not Hras or Nras, May Initiate Tumors of Endodermal Origin via Stem Cell Expansion
2008
Knockdown of Oncogenic KRAS in Non–Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy
2011
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Understanding Ras: ‘it ain’t over ’til it’s over’
2000
Inference and analysis of cell-cell communication using CellChat
2021 Standout
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
The Ras branch of small Gtpases: Ras family members don’t fall far from the tree
2000
Role of Ras and Mapks in TGFβ signaling
2000
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
RAS oncogenes: the first 30 years
2003
Lipid rafts and signal transduction
2000 Standout
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
2013 StandoutNature
Wildtype Kras2 can inhibit lung carcinogenesis in mice
2001
Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing
2002
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
M-Ras/R-Ras3, a Transforming Ras Protein Regulated by Sos1, GRF1, and p120 Ras GTPase-activating Protein, Interacts with the Putative Ras Effector AF6
1999
Ras signaling on the Golgi
2006
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Applying genomic and transcriptomic advances to mitochondrial medicine
2021
Disruption of the Mouse Rce1 Gene Results in Defective Ras Processing and Mislocalization of Ras within Cells
1999
Lung Cancer
2008 Standout
Hallmarks of aging: An expanding universe
2023 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans
1999
Ras history
2010
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
dpl-1 DP and efl-1 E2F Act with lin-35 Rb to Antagonize Ras Signaling in C. elegans Vulval Development
2001 StandoutNobel
Stable suppression of tumorigenicity by virus-mediated RNA interference
2002
Regulatory phases of early liver development: paradigms of organogenesis
2002
DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase
1989 StandoutNobel
Cancer genes and the pathways they control
2004 Standout
Upstream and downstream of mTOR
2004 Standout
Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer
2005 Standout
MAPK signal specificity: the right place at the right time
2006
Finding twinkle in the eyes of a 71‐year‐old lady: A case report and review of the genotypic and phenotypic spectrum of TWINKLE‐related dominant disease
2009
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
2001
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
2001 Nature
Human Splicing Finder: an online bioinformatics tool to predict splicing signals
2009 Standout
Targeting RAS signalling pathways in cancer therapy
2003 Standout
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
Signaling—2000 and Beyond
2000 Standout
The 5′ splice site: phylogetic evalution and variable geometry of association with U1RNA
1989
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Ras and relatives—job sharing and networking keep an old family together
2002
Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development
2012
Genetics of RAS signaling in C. elegans
1998
bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila
2003 Standout
Revealing the world of RNA interference
2004 StandoutNatureNobel
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Opposing Effects of Ras on p53
2000
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
New Insights into the Interaction of Ras with the Plasma Membrane
1999
ClinVar: public archive of interpretations of clinically relevant variants
2015 Standout
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral
1998
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains
1999
Cystic fibrosis population carrier screening: 2004 revision of American College of Medical Genetics mutation panel
2004
MOM-4, a MAP Kinase Kinase Kinase–Related Protein, Activates WRM-1/LIT-1 Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase
2006 StandoutNobel
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis
2011
CTR1, a negative regulator of the ethylene response pathway in arabidopsis, encodes a member of the Raf family of protein kinases
1993 Standout
RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression
1987 Standout
SELECTIVITY IN NEUROTROPHIN SIGNALING : Theme and Variations
2003
Small GTP-Binding Proteins
2001 Standout
Involvement of a Small GTP-binding Protein (G Protein) Regulator, Small G Protein GDP Dissociation Stimulator, in Antiapoptotic Cell Survival Signaling
2000
The Origin and Evolution of Retroposons
1985
Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
2006 StandoutScience
Deficiencies in Mouse Myh and Ogg1 Result in Tumor Predisposition and G to T Mutations in Codon 12 of the K-Ras Oncogene in Lung Tumors
2004 StandoutNobel
Molecular Determinants of Regulated Exocytosis
2002 StandoutNobel
Ca lectin gene insertion has the structural features of a transposable element
1983
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Concepts in Ras-directed therapy
1999
The internally located telomeric sequences in the germ-line chromosomes of tetrahymena are at the ends of transposon-like elements
1985 StandoutNobel
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
A catalogue of splice junction and putative branch point sequences from plant introns
1986
H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway
2000
A Ras by Any Other Name
2001
Structural Analysis of Plant Genes
1986
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
The scanning model for translation: an update.
1989 Standout
Works of Eric Schmitt being referenced
Use of MALDI-TOF mass spectrometry in a 51-mutation test for cystic fibrosis: Evidence that 3199del6 is a disease-causing mutation
2004
K-ras is an essential gene in the mouse with partial functional overlap with N-ras
1997
Mutations in the MPV17 gene are responsible for rapidly progressive liver failure in infancy
2007
Interpretation of mitochondrial tRNA variants
2020
Closely related families of genes code for the α and α‘ subunits of the soybean 7S storage protein complex
1982