Citation Impact
Citing Papers
Micelles Protect Membrane Complexes from Solution to Vacuum
2008 Science
Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review
2023 Standout
The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change
2008
Inhibition of the Striatal Specific Phosphodiesterase PDE10A Ameliorates Striatal and Cortical Pathology in R6/2 Mouse Model of Huntington's Disease
2010
Structural analysis of ibuprofen binding to human adipocyte fatty-acid binding protein (FABP4)
2015
Post-translational modification of the N-terminal His tag interferes with the crystallization of the wild-type and mutant SH3 domains from chicken src tyrosine kinase
2001 StandoutNobel
O-GlcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers
2014
The role of autophagy in neurodegenerative disease
2013 Standout
Structure-Based Drug Design Strategies in Medicinal Chemistry
2009
Improving known classes of antibiotics: an optimistic approach for the future
2012
NMR Spectroscopic Analysis of the First Two Steps of the Pentose-Phosphate Pathway Elucidates the Role of 6-Phosphogluconolactonase
2001
Specificity of receptor–ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRα
2005
Glyceryl‐S‐Acyl Carrier Protein as an Intermediate in the Biosynthesis of Tetronate Antibiotics
2007
The Gene Cluster for Fluorometabolite Biosynthesis in Streptomyces cattleya: A Thioesterase Confers Resistance to Fluoroacetyl-Coenzyme A
2006
Co-inoculation effect of plant-growth-promoting rhizobacteria and rhizobium on EDDS assisted phytoremediation of Cu contaminated soils
2020 Standout
Molecular determinants of drug–receptor binding kinetics
2013
The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment
2006
Molecular Dynamics Simulation for All
2018 Standout
Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols
2015
Tau in physiology and pathology
2015 Standout
Extensive Crosstalk between O-GlcNAcylation and Phosphorylation Regulates Akt Signaling
2012
The Science of Antibiotic Discovery
2020 Standout
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Principles of early drug discovery
2010 Standout
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Affinity purification of Car9-tagged proteins on silica matrices: Optimization of a rapid and inexpensive protein purification technology
2017
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
A Unique PPARγ Ligand with Potent Insulin-Sensitizing yet Weak Adipogenic Activity
2001
Advances in drug discovery and biochemical studies
2007 StandoutNobel
The enzymes of biotin dependent CO2 metabolism: What structures reveal about their reaction mechanisms
2012
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
The use of spirocyclic scaffolds in drug discovery
2014 Standout
The multiple roles of computational chemistry in fragment-based drug design
2009
Animal Models of Alzheimer Disease
2012
Structures of membrane proteins
2010 StandoutNobel
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
2015 Standout
Expression, purification and crystallization ofTrypanosoma cruzidihydroorotate dehydrogenase complexed with orotate
2005
Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases
2013
AKT/PKB Signaling: Navigating the Network
2017 Standout
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
2021 StandoutNobel
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
2010 StandoutNobel
New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition
2012
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
3d Transition Metals for C–H Activation
2018 Standout
Plant growth promoting bacteria confer salt tolerance in Vigna radiata by up-regulating antioxidant defense and biological soil fertility
2015
Epidemiological Expansion, Structural Studies, and Clinical Challenges of New β-Lactamases from Gram-Negative Bacteria
2010
Antibiotics and Bacterial Resistance in the 21st Century
2014 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Discovery of Imidazo[1,5-a]pyrido[3,2-e]pyrazines as a New Class of Phosphodiesterase 10A Inhibitiors
2010
Improving MM-GB/SA Scoring through the Application of the Variable Dielectric Model
2011
Sequence–Structure–Binding Relationships Reveal Adhesion Behavior of the Car9 Solid-Binding Peptide: An Integrated Experimental and Simulation Study
2020 StandoutNobel
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6
2014
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
2010 StandoutNobel
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation
2013 Standout
Shielded Hydrogen Bonds as Structural Determinants of Binding Kinetics: Application in Drug Design
2011
Directed Evolution ofVibrio fischeriLuxR for Improved Response to Butanoyl-Homoserine Lactone
2007 StandoutNobel
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Deciphering the Resistome of the Widespread Pseudomonas aeruginosa Sequence Type 175 International High-Risk Clone through Whole-Genome Sequencing
2016
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
2014 Standout
A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery
2019 Standout
Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology
2012 Standout
A Medicinal Chemist’s Guide to Molecular Interactions
2010 Standout
The Epidemiology of Carbapenem-Resistant Enterobacteriaceae: The Impact and Evolution of a Global Menace
2017 Standout
Copper-catalyzed benzylic C(sp3)–H alkoxylation of heterocyclic compounds
2014
Antimicrobial Resistance in ESKAPE Pathogens
2020 Standout
Targeting Antibiotic Resistance
2016
Works of Eric S. Marr being referenced
Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1 H -pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia†Coordinates of the PDE10A crystal structures have been deposited in the Protein Data Bank for compound 1 (3HQW), 2 (3HQY), 3 (3HQW) and 9 (3HR1).
2009
Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion
2011
Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2)
2006
Spontaneous α-N-6-Phosphogluconoylation of a “His Tag” inEscherichia coli:The Cause of Extra Mass of 258 or 178 Da in Fusion Proteins
1999
Synthesis and structure based optimization of novel Akt inhibitors
2008
A systematic study of 50S ribosomal subunit purification enabling robust crystallization
2009
Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains ofPseudomonas aeruginosa
2010
Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy
2009
Discovery of a Series of 6,7-Dimethoxy-4-pyrrolidylquinazoline PDE10A Inhibitors
2006