Citation Impact
Citing Papers
Why highly expressed proteins evolve slowly
2005 StandoutNobel
RelE toxins from Bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA
2003
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli -expressed libraries
2004
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Directed evolution of a genetic circuit
2002 StandoutNobel
Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat
2005 StandoutScienceNobel
Participation of 3′-to-5′ Exoribonucleases in the Turnover of Bacillus subtilis mRNA
2005
An Expanded Palette of Genetically Encoded Ca 2+ Indicators
2011 Science
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
Scaffolding as an Organizing Principle in Trans-translation
2006 StandoutNobel
The ClpXP Protease Unfolds Substrates Using a Constant Rate of Pulling but Different Gears
2013
Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase
2008 Nature
The CtsR regulator of stress response is active as a dimer and specifically degraded in vivo at 37°C
2000
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Amino Acid Starvation and Colicin D Treatment Induce A-site mRNA Cleavage in Escherichia coli
2008
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Structural aspects of non-ribosomal peptide biosynthesis
2004
Clp-mediated proteolysis in Gram-positive bacteria is autoregulated by the stability of a repressor
2001
Cleavage of the A Site mRNA Codon during Ribosome Pausing Provides a Mechanism for Translational Quality Control
2003
A synthetic oscillatory network of transcriptional regulators
2000 StandoutNature
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Renaissance in antibacterial discovery from actinomycetes
2008
Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis
2009 StandoutNobel
Directed evolution: new parts and optimized function
2009 StandoutNobel
Continuous evolution of base editors with expanded target compatibility and improved activity
2019
CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria
1999
ClpE, a novel type of HSP100 ATPase, is part of the CtsR heat shock regulon of Bacillus subtilis
1999
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Ultrasensitive fluorescent proteins for imaging neuronal activity
2013 StandoutNature
Sculpting the Proteome with AAA+ Proteases and Disassembly Machines
2004
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
The coming of age of de novo protein design
2016 StandoutNatureNobel
Protein–Protein Interactions in Multienzyme Megasynthetases
2008
Opportunities and challenges for a sustainable energy future
2012 StandoutNatureNobel
Chapter 5 The Role of 3′–5′ Exoribonucleases in RNA Degradation
2009
ClpXP, an ATP-powered unfolding and protein-degradation machine
2011
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Engineering explored
2014 StandoutNatureNobel
Genetic Identification of Nascent Peptides That Induce Ribosome Stalling
2009
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Directed evolution drives the next generation of biocatalysts
2009
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
Ribosome Stalling during Translation Elongation Induces Cleavage of mRNA Being Translated in Escherichia coli
2004
Exploring protein fitness landscapes by directed evolution
2009 StandoutNobel
Cold shock induction of RNase R and its role in the maturation of the quality control mediator SsrA/tmRNA
2003
A surprising simplicity to protein folding
2000 StandoutNatureNobel
The Bacterial Toxin RelE Displays Codon-Specific Cleavage of mRNAs in the Ribosomal A Site
2003
In vitro selection and evolution of proteins
2001
The molecular chaperone Hsp104—A molecular machine for protein disaggregation
2006
In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes
2018 StandoutNobel
Posttranslational Quality Control: Folding, Refolding, and Degrading Proteins
1999 Science
Computational Design of an α-Gliadin Peptidase
2012 StandoutNobel
Ribosomal Synthesis of N-Methyl Peptides
2008 StandoutNobel
Computational structure-based redesign of enzyme activity
2009
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
The N-terminal to C-terminal motif in protein folding and function
2005
Bacterial scaffold directs pole-specific centromere segregation
2014 StandoutNobel
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Biosynthesis of Nonribosomal Peptides
2004
Proteolysis of the Caulobacter McpA Chemoreceptor Is Cell Cycle Regulated by a ClpX-Dependent Pathway
2001
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution
2011 StandoutNobel
Quality Control Mechanisms During Translation
1999 Science
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids
2006 StandoutNobel
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
The Small RNA Regulators ofEscherichia coli: Roles and Mechanisms
2004
Trapping of a Spatial Transient State During the Framework Transformation of a Porous Coordination Polymer
2014 StandoutNobel
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
Directed Evolution of Protein Catalysts
2018
Stochastic Gene Expression in a Single Cell
2002 StandoutScience
Visualizing tmRNA Entry into a Stalled Ribosome
2003 StandoutScienceNobel
Reiterative Recombination for the in vivo assembly of libraries of multigene pathways
2011
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease
2009
Messenger RNA Degradation in Bacterial Cells
2014
Asymmetric Catalysis of the Carbonyl-Amine Condensation: Kinetic Resolution of Primary Amines
2017 StandoutNobel
Chaperone rings in protein folding and degradation
1999
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
2012 StandoutNobel
Cryo-EM visualization of transfer messenger RNA with two SmpBs in a stalled ribosome
2006 StandoutNobel
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of theMycobacterium tuberculosisvirulence factor Sulfolipid-1
2007 StandoutNobel
Mycobacterial polyketide-associated proteins are acyltransferases: Proof of principle with Mycobacterium tuberculosis PapA5
2004
Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium
2007 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Simulating the pulling of stalled elongated peptide from the ribosome by the translocon
2013 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
2014 StandoutNobel
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Eric Roche being referenced
The SsrA–SmpB system for protein tagging, directed degradation and ribosome rescue
2000
Evidence for a Monomeric Structure of Nonribosomal Peptide Synthetases
2002
The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system
1998
Identification of Endogenous SsrA-tagged Proteins Reveals Tagging at Positions Corresponding to Stop Codons
2001
SsrA-mediated peptide tagging caused by rare codons and tRNA scarcity
1999
Design, synthesis, and biological evaluation of BODIPY®–erythromycin probes for bacterial ribosomes
2005
Dissection of the EntF Condensation Domain Boundary and Active Site Residues in Nonribosomal Peptide Synthesis
2003
Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes
2007