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Rapid deconvolution of combinatorial libraries using HPLC fractionation
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Synthesis and Applications of Small Molecule Libraries
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1996 StandoutScience
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2000
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1998
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Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides
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2000
The “One-Bead-One-Compound” Combinatorial Library Method
1997
Comprehensive Survey of Combinatorial Library Synthesis: 1998
1999
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1997
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Parallel Synthesis and Screening of a Solid Phase Carbohydrate Library
1996 Science
Asymmetric Enamine Catalysis
2007 StandoutNobel
Rapid microscale synthesis: Solution phase parallel synthesis of a library of piperazines and piperidines using a water soluble base
1998
The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver
2000 Standout
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1998
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1998
Rapid Assembly of Matrix Metalloprotease Inhibitors Using Click Chemistry
2006
Solid-phase synthesis of functionalized 1,2,3-triazoles
2002
Aminodiol HIV protease inhibitors. 2. 1,1-Dimethyl-2-hydroxyethyl carbamate derivatives with enhanced potency
1995
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
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A new vinyl ether type linker for solid-phase synthesis
2000
Recent developments in the design of angiotensin‐converting enzyme inhibitors
1985
Revolutionizing Resin Handling for Combinatorial Synthesis
2001
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Dynamic diversity in drug discovery: Putting small-molecule evolution to work
2000
Rapid microwave-assisted Suzuki coupling on solid-phase
1996
Partially Modified Retro-Inverso Peptides: Development, Synthesis, and Conformational Behavior
1998
Radiofrequency Encoded Combinatorial Chemistry
1995
The solid phase synthesis of oligoureas
1996
Works of Eric M. Gordon being referenced
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1998
Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions
1994
In situ assembly of enzyme inhibitors using extended tethering
2003
Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis
1990
Phosphinyl Acid-Based Bisubstrate Analog Inhibitors of Farnesyl Protein Transferase
1995
Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetase
1988
Isoprenyl phosphinylformates: new inhibitors of squalene synthetase
1991
Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety
1991
Combinatorial modification of natural products: Preparation of unencoded and encoded libraries of Rauwolfia alkaloids
1996
Combinatorial synthesis and screening of a chemical library of 1,4-dihydropyridine calcium channel blockers
1998
Amino Diol HIV Protease Inhibitors. 1. Design, Synthesis, and Preliminary SAR
1994
Design of novel inhibitors of aminopeptidases. Synthesis of peptide-derived diamino thiols and sulfur replacement analogs of bestatin
1988
Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries
1994
Identification of potent and novel small-Molecule inhibitors of caspase-3
2003
Combinatorial modification of natural products: synthesis and in vitro analysis of derivatives of thiazole peptide antibiotic GE2270 A: A-ring modifications
2003
Ketomethyldipeptides II. Effect of modifications of the α-aminoketone portion on inhibition of angiotensin converting enzyme
1984
Approaches to Combinatorial Synthesis of Heterocycles: A Solid-Phase Synthesis of 1,4-Dihydropyridines
1996
Synthesis of peptide-derived amino alcohols. 1. Potential transition-state inhibitors of angiotensin-converting enzyme
1986
Encoded combinatorial chemistry: Synthesis and screening of a library of highly functionalized pyrrolidines
1997
Ras farnesylation as a target for novel antitumor agents: Potent and selective farnesyl diphosphate analog inhibitors of farnesyltransferase
1995
Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design
2002
Strategy and Tactics in Combinatorial Organic Synthesis. Applications to Drug Discovery
1996
Strategies for Combinatorial Organic Synthesis: Solution and Polymer-Supported Synthesis of 4-Thiazolidinones and 4-Metathiazanones Derived from Amino Acids
1995
Design of conformationally constrained angiotensin-converting enzyme inhibitors
1984
Approaches to combinatorial synthesis of heterocycles: Solid phase synthesis of pyridines and pyrido[2,3-d]pyrimidines
1996
The first potent inhibitor of squalene synthase: a profound contribution of an ether oxygen to inhibitor-enzyme interaction
1991
Solid-Supported Combinatorial Synthesis of Structurally Diverse β-Lactams
1996
Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library
1995
Combinatorial chemistry of natural products: Solid phase synthesis of D- and L-cycloserine derivatives
1998
Site-directed ligand discovery
2000
Versatile Approach To Encoding Combinatorial Organic Syntheses Using Chemically Robust Secondary Amine Tags
1996
A general and efficient solid phase synthesis of quinazoline-2,4-diones
1997
Design of peptide derived amino alcohols as transition-state analog inhibitors of angiotensin converting enzyme
1985
Solid-Phase Synthesis of β-Sultams
1997
Libraries of non-polymeric organic molecules
1995
O-Sulfated .beta.-lactam hydroxamic acids (monosulfactams). Novel monocyclic .beta.-lactam antibiotics of synthetic origin
1982
Ketomethyldipeptides I. A new class of angiotensin converting enzyme inhibitors
1984
The identification of cyclooxygenase-1 inhibitors from 4-thiazolidinone combinatorial libraries
1996